A rapid screening for cytochrome P450 catalysis on new chemical entities: Cytochrome P450 BM3 and 1,2,5-oxadiazole derivatives

Journal of Biomolecular Screening

Volumn 18, Issue 2, 2013, Pages 211-218

  Tsotsou, Georgia E ^a   Di Nardo, Giovanna ^a   Sadeghi, Sheila J ^a   Fruttero, Roberta ^a   Lazzarato, Loretta ^a   Bertinaria, Massimo ^a   Gilardi, Gianfranco ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

enzyme assays; enzyme kinetics; protein arrays; protein chemistry; proteomics; structure activity relationships; toxicology

Indexed keywords

CAS 1609; CYTOCHROME P450 BM3; LAURIC ACID; OXADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS MEGATERIUM; BINDING AFFINITY; CATALYSIS; CATALYST; CONTROLLED STUDY; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR DOCKING; OXIDATION; PRIORITY JOURNAL;

BACILLUS MEGATERIUM; CATALYSIS; CATALYTIC DOMAIN; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME ACTIVATION; ENZYME ASSAYS; KINETICS; MOLECULAR DOCKING SIMULATION; NADP; OXADIAZOLES; PROTEIN BINDING;

BACILLUS MEGATERIUM; MAMMALIA;

EID: 84871690832     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057112459351     Document Type: Article

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