Endothelial cells incubated with platelet-rich plasma express PDGF-B and ICAM-1 and induce bone marrow stromal cell migration

Journal of Orthopaedic Research

Volumn 27, Issue 11, 2009, Pages 1493-1498

  Cenni, Elisabetta ^a   Ciapetti, Gabriela ^a   Granchi, Donatella ^a   Fotia, Caterina ^a,b   Perut, Francesca ^a   Giunti, Armando ^a,b   Baldini, Nicola ^a,b  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Bone marrow stromal cells; Bone repair; Endothelial cells; Platelet rich plasma; Vascular endothelial growth factor

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PLATELET DERIVED GROWTH FACTOR B; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; VASCULOTROPIN A;

ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; BONE REMODELING; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE AMPLIFICATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL; THROMBOCYTE COUNT; THROMBOCYTE POOR PLASMA; THROMBOCYTE RICH PLASMA; UMBILICAL VEIN;

AGED; BONE MARROW CELLS; CELL MOVEMENT; CELL PROLIFERATION; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; PLATELET-RICH PLASMA; PROTO-ONCOGENE PROTEINS C-SIS; STROMAL CELLS; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 70350212677     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20896     Document Type: Article

References (15)

1. Kilian O, Flesch I, Wenisch S, et al. 2004. Effects of platelet growth factors on human mesenchymal stem cells and human endothelial cells in vitro. Eur J Med Res 9:337-344.
2. Towler DA. 2008. The osteogenic-angiogenic interface: novel insights into the biology of bone formation and fracture repair. Curr Osteoporos Rep 6:67-71.
3. Yu H, Vandevord PJ, Gong W, et al. 2008. Promotion of osteogenesis in tissue-engineered bone by pre-seeding endothelial progenitor cells-derived endothelial cells. J Orthop Res 26:1147-1152.
4. Brandi ML, Collin-Osdoby P. 2006. Vascular biology and the skeleton. J Bone Miner Res 21:183-192.
5. Ciapetti G, Ambrosio L, Marletta G, et al. 2006. Human bone marrow stromal cells: In vitro expansion and differentiation for bone engineering. Biomaterials 27:6150-6160.
6. Cenni E, Perut F, Ciapetti G, et al. 2009. In vitro evaluation of freeze-dried bone allografts combined with platelet rich plasma and human bone marrow stromal cells for tissue engineering. J Mater Sci Mater Med 20:45-50.
7. Filvaroff EH. 2003. VEGF and bone. J Musculoskel Neuron Interact 3:304-307.
8. Namkoong S, Lee SJ, Kim CK, et al. 2005. Prostaglandin E2 stimulates angiogenesis by activating the nitric oxide/cGMP pathway in human umbilical vein endothelial cells. Exp Mol Med 37:588-600. (Pubitemid 43143521)
9. Axelrad TW, Deo DD, Ottino P, et al. 2004. Platelet-activating factor (PAF) induces activation of matrix metalloproteinase 2 activity and vascular endothelial cell invasion and migration. FASEB J 18:568-570.
10. Fiedler J, Etzel N, Brenner RE. 2004. To go or not to go: migration of human mesenchymal progenitor cells stimulated by isoforms of PDGF. J Cell Biochem 93:990-998. (Pubitemid 44264152)
11. Kim I, Moon SO, Kim SH, et al. 2001. Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells. J Biol Chem 276:7614-7620. (Pubitemid 37392076)
12. Yukami T, Hasegawa M, Matsushita Y, et al. 2007. Endothelial selectins regulate skin wound healing in cooperation with L-selectin and ICAM-1. J Leukoc Biol 82:519-531. (Pubitemid 47367142)
13. Kon T, Cho TJ, Aizawa T, et al. 2001. Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing. J Bone Miner Res 16:1004-1014. (Pubitemid 32467144)
14. Collin-Osdoby P, Rothe L, Anderson F, et al. 2001. Receptor activator of NF-κB and osteoprotegerin expression by human microvascular endothelial cells, regulated by inflammatory cytokines and role in human osteoclastogenesis. J Biol Chem 276:20659-20672. (Pubitemid 37411154)
15. Takai H, Kanematsu M, Yano K, et al. 1998. Transforming growth factor-β stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells. J Biol Chem 273:27091-27096. (Pubitemid 28500414)