Cytosolic Ca2+-induced apoptosis in rat cardiomyocytes via mitochondrial NO-cGMP-protein kinase G pathway

Journal of Pharmacology and Experimental Therapeutics

Volumn 344, Issue 1, 2013, Pages 77-84

  Seya, Kazuhiko ^a   Ono, Kyoichi ^b   Fujisawa, Susumu ^b   Okumura, Ken ^a   Motomura, Shigeru ^a   Furukawa, Ken Ichi ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 2 (4 CARBOXYPHENYL) 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; 4,4' DIISOTHIOCYANO 2 2' DISULFONIC ACID STILBENE; CALCIUM ION; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLOSPORIN A; CYTOCHROME C; EGTAZIC ACID; KT 5823; LIPOCORTIN 5; N(G) MONOMETHYL L ARGININE MONOACETATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; STILBENE DERIVATIVE; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL; VOLTAGE DEPENDENT ANION CHANNEL INHIBITOR; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 8 BROMO CYCLIC GMP; 8-BROMOCYCLIC GMP; CALCIUM; CYCLIC GMP; DRUG DERIVATIVE; NITRIC OXIDE SYNTHASE; SCAVENGER;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOLIC FRACTION; DOSE RESPONSE; ENZYME ACTIVITY; HEART CELL CULTURE; HEART LEFT VENTRICLE; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE PERFUSION; ISOLATED HEART; MALE; MITOCHONDRIAL PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CALCIUM SIGNALING; CELL CULTURE; CELL SEPARATION; CYTOSOL; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION SWELLING; PATCH CLAMP; PHYSIOLOGY; WISTAR RAT;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; ANIMALS; APOPTOSIS; CALCIUM; CALCIUM SIGNALING; CELL SEPARATION; CELLS, CULTURED; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; CYTOSOL; FREE RADICAL SCAVENGERS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, HEART; MITOCHONDRIAL SWELLING; MYOCYTES, CARDIAC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR;

EID: 84871685210     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.198176     Document Type: Article

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