Postexposure application of fas receptor small-interfering RNA to suppress sulfur mustard-induced apoptosis in human airway epithelial cells: Implication for a therapeutic approach

Journal of Pharmacology and Experimental Therapeutics

Volumn 344, Issue 1, 2013, Pages 308-316

  Keyser, Brian M ^a   Andres, Devon K ^a   Nealley, Eric ^a   Holmes, Wesley W ^a   Benton, Betty ^a   Paradiso, Danielle ^a   Appell, Ashley ^a   Carpin, Chris ^a   Anderson, Dana R ^a   Smith, William J ^a   Ray, Radharaman ^a  

^a US ARMY MEDICAL RESEARCH INSTITUTE OF CHEMICAL DEFENSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; FAS ANTIGEN; FAS LIGAND; MUSTARD GAS; RECEPTOR ANTIBODY; RECEPTOR ANTIBODY CH11; RECEPTOR ANTIBODY ZB4; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN FUNCTION; APOPTOSIS; ARTICLE; CELL DEATH; CELL POPULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE CONTROL; DRUG ANTAGONISM; DRUG INHIBITION; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; LUNG INJURY; LUNG LAVAGE; MALE; NONHUMAN; POST EXPOSURE PROPHYLAXIS; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RECEPTOR BLOCKING; RESPIRATORY EPITHELIUM;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; BURNS, INHALATION; CASPASE 3; CELL LINE; CELLS, CULTURED; CHEMICAL WARFARE AGENTS; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FAS LIGAND PROTEIN; FLOW CYTOMETRY; HUMANS; MALE; MUSTARD GAS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY SYSTEM; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84871677852     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.199935     Document Type: Article

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