Genetic copy number variants in myocardial infarction patients with hyperlipidemia

10th Int. Conference on Bioinformatics - 1st ISCB Asia Joint Conference 2011, InCoB 2011/ISCB-Asia 2011: Computational Biology - Proceedings from Asia Pacific Bioinformatics Network (APBioNet)

Volumn 12, Issue SUPPL. 3, 2011, Pages

  Shia, Wei Chung ^a   Ku, Tien Hsiung ^b   Tsao, Yu Ming ^c   Hsia, Chien Hsun ^b   Chang, Yung Ming ^b   Huang, Ching Hui ^b   Chung, Yeh Ching ^d   Hsu, Shih Lan ^e   Liang, Kae Woei ^e   Hsu, Fang Rong ^a  

^a FENG CHIA UNIVERSITY   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^d NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^e TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS; CHROMOSOMES; DIAGNOSIS; DISEASES; POLYMERASE CHAIN REACTION;

CARDIO-VASCULAR DISEASE; COMPLEX DISEASE; COPY NUMBER VARIATIONS; EARLY-STAGE DIAGNOSIS; GENOME-WIDE ASSOCIATION STUDIES; MYOCARDIAL INFARCTION; MYOCARDIAL INFARCTION PATIENTS; QUANTITATIVE REAL TIME PCR;

CARDIOLOGY;

CHOLESTEROL; LOW DENSITY LIPOPROTEIN;

ADULT; AGED; ARTICLE; BLOOD; COPY NUMBER VARIATION; FEMALE; GENETIC ASSOCIATION; GENETICS; HEART INFARCTION; HUMAN; HYPERLIPIDEMIA; MALE; MIDDLE AGED; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; CHOLESTEROL; DNA COPY NUMBER VARIATIONS; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; HYPERLIPIDEMIAS; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 84871635936     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1186/1471-2164-12-S3-S23     Document Type: Conference Paper

References (35)

1. Assmann G, Schulte H: Relation of high-density lipoprotein cholesterol and triglycerides to incidence of atherosclerotic coronary artery disease (the PROCAM experience). Prospective Cardiovascular Munster study. Am J Cardiol 1992, 70(7):733-737.
2. Ross R, Harker L: Hyperlipidemia and atherosclerosis. Science 1976, 193(4258):1094-1100.
3. Allayee H, Dominguez KM, Aouizerat BE, Krauss RM, Rotter JI, Lu J, Cantor RM, de Bruin TW, Lusis AJ: Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia. J Lipid Res 2000, 41(2):245-252.
4. Assmann G: Genes and dyslipoproteinaemias. Eur Heart J 1990, 11(Suppl H):4-8.
5. Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann HE, et al: Genomewide association analysis of coronary artery disease. The New England journal of medicine 2007, 357(5):443-453.
6. Shen GQ, Li L, Rao S, Abdullah KG, Ban JM, Lee BS, Park JE, Wang QK: Four SNPs on chromosome 9p21 in a South Korean population implicate a genetic locus that confers high cross-race risk for development of coronary artery disease. Arterioscl Throm Vas 2008, 28(2):360-365.
7. Shen GQ, Rao SQ, Martinelli N, Li L, Olivieri O, Corrocher R, Abdullah KG, Hazen SL, Smith J, Barnard J, et al: Association between four SNPs on chromosome 9p21 and myocardial infarction is replicated in an Italian population. J Hum Genet 2008, 53(2):144-150.
8. Stranger BE, Forrest MS, Dunning M, Ingle CE, Beazley C, Thorne N, Redon R, Bird CP, de Grassi A, Lee C, et al: Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science 2007, 315(5813):848-853.
9. Perry GH, Ben-Dor A, Tsalenko A, Sampas N, Rodriguez-Revenga L, Tran CW, Scheffer A, Steinfeld I, Tsang P, Yamada NA, et al: The fine-scale and complex architecture of human copy-number variation. Am J Hum Genet 2008, 82(3):685-695.
10. Walsh T, McClellan JM, McCarthy SE, Addington AM, Pierce SB, Cooper GM, Nord AS, Kusenda M, Malhotra D, Bhandari A, et al: Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 2008, 320(5875):539-543.
11. Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, Yamrom B, Yoon S, Krasnitz A, Kendall J, et al: Strong association of de novo copy number mutations with autism. Science 2007, 316(5823):445-449.
12. Lanktree M, Hegele RA: Copy number variation in metabolic phenotypes. Cytogenet Genome Res 2008, 123(1-4):169-175.
13. McCarroll SA, Altshuler DM: Copy-number variation and association studies of human disease. Nat Genet 2007, 39(7 Suppl):S37-S42.
14. Yip AG, Ma Q, Wilcox M, Panhuysen CI, Farrell J, Farrer LA, Wyszynski DF: Search for genetic factors predisposing to atherogenic dyslipidemia. BMC Genet 2003, 4(Suppl 1):S100.
15. Shmulewitz D, Heath SC, Blundell ML, Han Z, Sharma R, Salit J, Auerbach SB, Signorini S, Breslow JL, Stoffel M, et al: Linkage analysis of quantitative traits for obesity, diabetes, hypertension, and dyslipidemia on the island of Kosrae, Federated States of Micronesia. Proc Natl Acad Sci U S A 2006, 103(10):3502-3509.
16. Chia MC: The role of adhesion molecules in atherosclerosis. Crit Rev Clin Lab Sci 1998, 35(6):573-602.
17. Dong C, Beecham A, Wang L, Slifer S, Wright CB, Blanton SH, Rundek T, Sacco RL: Genetic loci for blood lipid levels identified by linkage and association analyses in Caribbean Hispanics. J Lipid Res 2011.
18. Ryu JK, Zhang LW, Jin HR, Piao S, Choi MJ, Tuvshintur B, Tumurbaatar M, Shin SH, Han JY, Kim WJ, et al: Derangements in endothelial cell-to-cell junctions involved in the pathogenesis of hypercholesterolemia-induced erectile dysfunction. J Sex Med 2009, 6(7):1893-1907.
19. Kathiresan S, Wilier CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, et al: Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009, 41(1):56-65.
20. Assmann G, Schulte H: The Prospective Cardiovascular Munster (PROCAM) study: prevalence of hyperlipidemia in persons with hypertension and/or diabetes mellitus and the relationship to coronary heart disease. Am Heart J 1988, 116(6 Pt 2):1713-1724.
21. Benjamin EJ, Wolf PA, D'Agostino RB, Silbershatz H, Kannel WB, Levy D: Impact of atrial fibrillation on the risk of death: the Framingham Heart Study. Circulation 1998, 98(10):946-952.
22. Pajak A, Broda G, Abernathy JR, Sznajd J, Rywik S, Irving SH, Czarnecka H, Wagrowska H, Thomas RP, Celinski A, et al: Poland-US collaborative study on cardiovascular epidemiology: classification agreement between US National Cholesterol Education Program and European Atherosclerosis Society hyperlipidemia guidelines in selected Polish and US populations. Atherosclerosis 1992, 95(1):43-50.
23. The International HapMap Project. Nature 2003, 426(6968):789-796.
24. Edgar R, Domrachev M, Lash AE: Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 2002, 30(1):207-210.
25. Zhang J, Feuk L, Duggan GE, Khaja R, Scherer SW: Development of bioinformatics resources for display and analysis of copy number and other structural variants in the human genome. Cytogenet Genome Res 2006, 115(3-4):205-214.
26. Iafrate AJ, Feuk L, Rivera MN, Listewnik ML, Donahoe PK, Qi Y, Scherer SW, Lee C: Detection of large-scale variation in the human genome. Nat Genet 2004, 36(9):949-951.
27. Pruitt KD, Tatusova T, Klimke W, Maglott DR: NCBI Reference Sequences: current status, policy and new initiatives. Nucleic Acids Res 2009, 37(Database issue):D32-36.
28. Drummond AJ, Ashton B, Buxton S, Cheung M, Cooper A, Duran C, Field M, Heled J, Kearse M, Markowitz S, Moir R, Stones-Havas S, Sturrock S, Thierer T, Wilson A: Geneious v5.4. 2011, Available from http://www.geneious.com/.
29. Brouwers MC, Cantor RM, Kono N, Yoon JL, van der Kallen CJ, Bilderbeek- Beckers MA, van Greevenbroek MM, Lusis AJ, de Bruin TW: Heritability and genetic loci of fatty liver in familial combined hyperlipidemia. J Lipid Res 2006, 47(12):2799-2807.
30. Kiechl S, Laxton RC, Xiao Q, Hernesniemi JA, Raitakari OT, Kahonen M, Mayosi BM, Jula A, Moilanen L, Willeit J, et al: Coronary artery diseaserelated genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis. Arterioscler Thromb Vasc Biol 2010, 30(12):2678-2683.
31. Samani NJ, Deloukas P, Erdmann J, Hengstenberg C, Kuulasmaa K, McGinnis R, Schunkert H, Soranzo N, Thompson J, Tiret L, et al: Large scale association analysis of novel genetic loci for coronary artery disease. Arterioscler Thromb Vasc Biol 2009, 29(5):774-780.
32. Eijgelsheim M, Newton-Cheh C, Sotoodehnia N, de Bakker PI, Muller M, Morrison AC, Smith AV, Isaacs A, Sanna S, Dorr M, et al: Genome-wide association analysis identifies multiple loci related to resting heart rate. Hum Mol Genet 2010, 19(19):3885-3894.
33. Johnson AD, Kavousi M, Smith AV, Chen MH, Dehghan A, Aspelund T, Lin JP, van Duijn CM, Harris TB, Cupples LA, et al: Genome-wide association meta-analysis for total serum bilirubin levels. Hum Mol Genet 2009, 18(14):2700-2710.
34. Ruixing Y, Dezhai Y, Shuquan L, Yuming C, Hanjun Y, Qiming F, Shangling P, Weixiong L, Jing T, Yiyang L: Hyperlipidaemia and its risk factors in the Guangxi Bai Ku Yao and Han populations. Public Health Nutr 2009, 12(6):816-824.
35. Avramoglu RK, Qiu W, Adeli K: Mechanisms of metabolic dyslipidemia in insulin resistant states: deregulation of hepatic and intestinal lipoprotein secretion. Front Biosci 2003, 8:d464-476.