Cationic nanoparticles have superior transvascular flux into solid tumors: Insights from a mathematical model

Annals of Biomedical Engineering

Volumn 41, Issue 1, 2013, Pages 68-77

  Stylianopoulos, Triantafyllos ^a   Soteriou, Konstantinos ^a   Fukumura, Dai ^b   Jain, Rakesh K ^b  

^a UNIVERSITY OF CYPRUS   (Cyprus)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Cancer therapy; Electrostatic and hydrodynamic interactions; Nanomedicine; Surface charge density; Vascular permeability

Indexed keywords

CANCER THERAPY; CATIONIC CHARGES; CATIONIC NANOPARTICLES; CLINICAL USE; ELECTROSTATIC ATTRACTIONS; ELECTROSTATIC REPULSION; HYDRODYNAMIC INTERACTION; INTERSTITIAL SPACE; LARGE PARTS; MODEL PREDICTION; NANO SCALE; NANOPARTICLE FORMULATION; NANOPARTICLE SIZES; OPTIMAL DESIGN; SOLID TUMORS; VASCULAR PERMEABILITY; VESSEL WALLS;

CHARGE DENSITY; ELECTROSTATICS; MATHEMATICAL MODELS; MEDICAL NANOTECHNOLOGY; ONCOLOGY; SURFACE CHARGE; SURFACE CHEMISTRY; TUMORS;

NANOPARTICLES;

CATION; NANOPARTICLE;

ARTICLE; CAPILLARY PERMEABILITY; CHEMISTRY; DRUG DELIVERY SYSTEM; METABOLISM; NEOPLASM; OSMOLARITY; STATIC ELECTRICITY; THEORETICAL MODEL; VASCULARIZATION;

CAPILLARY PERMEABILITY; CATIONS; DRUG DELIVERY SYSTEMS; MODELS, THEORETICAL; NANOPARTICLES; NEOPLASMS; OSMOLAR CONCENTRATION; STATIC ELECTRICITY;

EID: 84871632852     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-012-0630-4     Document Type: Article

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