Establishment of consomic strains derived from A/J and SM/J mice for genetic analysis of complex traits

Mammalian Genome

Volumn 23, Issue 11-12, 2012, Pages 764-769

  Ohno, Tamio ^a   Hata, Keiko ^a   Baba, Taisuke ^a   Io, Fusayo ^b   Kobayashi, Misato ^b   Horio, Fumihiko ^b   Nishimura, Masahiko ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; GENOMIC DNA; LIPID;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; BREEDING; CHOLESTEROL BLOOD LEVEL; CHROMOSOME 11; CHROMOSOME 12; CHROMOSOME 6; CHROMOSOME SUBSTITUTION STRAIN; FEMALE; GENE MAPPING; GENETIC ANALYSIS; GENETIC STRAIN; GENETIC TRAIT; LIPID BLOOD LEVEL; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; OBSERVATION; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; RECIPIENT;

ANIMALS; BODY WEIGHT; BREEDING; CHROMOSOMES; CROSSES, GENETIC; HYBRIDIZATION, GENETIC; LIPIDS; MICE; MICE, INBRED STRAINS; QUANTITATIVE TRAIT LOCI;

MUS;

EID: 84871616084     PISSN: 09388990     EISSN: 14321777     Source Type: Journal    
DOI: 10.1007/s00335-012-9435-x     Document Type: Article

References (31)

1. Anunciado RV, Ohno T, Mori M, Ishikawa A, Tanaka S, Horio F, Nishimura M, Namikawa T (2000) Distribution of body weight, blood insulin and lipid levels in the SMXA recombinant inbred strains and the QTL analysis. Exp Anim 49:217-224
2. Anunciado RV, Nishimura M, Mori M, Ishikawa A, Tanaka S, Horio F, Ohno T, Namikawa T (2001) Quantitative trait loci for body weight in the intercross between SM/J and A/J mice. Exp Anim 50:319-324
3. 2 mice. Exp Anim 52:37-42
4. Brockmann GA, Bevova MR (2002) Using mouse models to dissect the genetics of obesity. Trends Genet 18:367-376
5. Cheverud JM, Routman EJ, Duarte FA, van Swinderen B, Cothran K, Perel C (1996) Quantitative trait loci for murine growth. Genetics 142:1305-1319
6. Colinayo VV, Qiao JH, Wang X, Krass KL, Schadt E, Lusis AJ, Drake TA (2003) Genetic loci for diet-induced atherosclerotic lesions and plasma lipids in mice. Mamm Genome 14:464-471
7. Darvasi A (1998) Experimental strategies for the genetic dissection of complex traits in animal models. Nat Genet 18:19-24
8. Festing MF (1996) Origins and characteristics of inbred strains of mice. In: Lyon MF, Rasten S, Brown SDM (eds) Genetic variants and strains of the laboratory mouse. Oxford University Press, New York, pp 1537-1576
9. Gregorová S, Divina P, Storchova R, Trachtulec Z, Fotopulosova V, Svenson KL, Donahue LR, Paigen B, Forejt J (2008) Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Res 18:509-515
10. Hada N, Kobayashi M, Fujiyoshi M, Ishikawa A, Kuga M, Nishimura M, Ebihara S, Ohno T, Horio F (2008) Quantitative trait loci for impaired glucose tolerance in nondiabetic SM/J and A/J mice. Physiol Genomics 35:65-74
11. Hill AE, Lander ES, Nadeau JH (2006) Chromosome substitution strains: a new way to study genetically complex traits. Methods Mol Med 128:153-172
12. Ho M, Post CM, Donahue LR, Lidov HG, Bronson RT, Goolsby H, Watkins SC, Cox GA, Brown RH Jr (2004) Disruption of muscle membrane and phenotype divergence in two novel mouse models of dysferlin deficiency. Hum Mol Genet 13:1999-2010
13. Ishih A, Ohno T, Nishimura M, Terada M (2000) Genetic analysis of mortality in murine angiostrongyliasis costaricensis using SMXA recombinant inbred mouse strains. Parasitol Int 49:335-338
14. Kobayashi M, Ohno T, Tsuji A, Nishimura M, Horio F (2003) Combinations of nondiabetic parental genomes elicit impaired glucose tolerance in mouse SMXA recombinant inbred strains. Diabetes 52:180-186
15. Kobayashi M, Ohno T, Hada N, Fujiyoshi M, Kuga M, Nishimura M, Murai A, Horio F (2010) Genetic analysis of abdominal fat distribution in SM/J and A/J mice. J Lipid Res 51:3463-3469
16. Kumazawa M, Kobayashi M, Io F, Kawai T, Nishimura M, Ohno T, Horio F (2007) Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat diet. J Lipid Res 48:2039-2046
17. Lyons MA, Korstanje R, Li R, Walsh KA, Churchill GA, Carey MC, Paigen B (2004) Genetic contributors to lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and RIIIS/J inbred mice. Physiol Genomics 17:114-121
18. Moore KJ, Nagle DL (2000) Complex trait analysis in the mouse: the strengths, the limitations and the promise yet to come. Annu Rev Genet 34:653-686
19. Nadeau JH, Singer JB, Matin A, Lander ES (2000) Analysing complex genetic traits with chromosome substitution strains. Nat Genet 24:221-225
20. Nishimura M, Hirayama N, Serikawa T, Kanehira K, Matsushima Y, Katoh H, Wakana S, Kojima A, Hiai H (1995) The SMXA: a new set of recombinant inbred strain of mice consisting of 26 substrains and their genetic profile. Mamm Genome 6:850-857
21. Ohno T, Katoh J, Kikkawa Y, Yonekawa H, Nishimura M (2003) Improved strain distribution patterns of SMXA recombinant inbred strains by microsatellite markers. Exp Anim 52:415-417
22. Pataer A, Nishimura M, Kamoto T, Ichioka K, Sato M, Hiai H (1997) Genetic resistance to urethan-induced pulmonary adenomas in SMXA recombinant inbred mouse strains. Cancer Res 57:2904-2908
23. Purcell-Huynh DA, Weinreb A, Castellani LW, Mehrabian M, Doolittle MH, Lusis AJ (1995) Genetic factors in lipoprotein metabolism. Analysis of a genetic cross between inbred mouse strains NZB/BINJ and SM/J using a complete linkage map approach. J Clin Invest 96:1845-1858
24. Silver LM (1995) Genetic markers. In: Silver LM (ed) Mouse genetics: concepts and applications. Oxford University Press, New York, pp 159-194
25. Singer JB, Hill AE, Burrage LC, Olszens KR, Song J, Justice M, O'Brien WE, Conti DV, Witte JS, Lander ES, Nadeau JH (2004) Genetic dissection of complex traits with chromosome substitution strains of mice. Science 304:445-448
26. Suzuki T, Ishikawa A, Nishimura M, Yoshimura T, Namikawa T, Ebihara S (2000) Mapping quantitative trait loci for circadian behavioral rhythms in SMXA recombinant inbred strains. Behav Genet 30:447-453
27. Takada T, Mita A, Maeno A, Sakai T, Shitara H, Kikkawa Y, Moriwaki K, Yonekawa H, Shiroishi T (2008) Mouse inter-subspecific consomic strains for genetic dissection of quantitative complex traits. Genome Res 18:500-508
28. Tanaka S, Matsuzawa A, Kato H, Esaki K, Sudo K, Yamanouchi K (1987) Inbred strains of mice maintained at the institute of medical science, University of Tokyo. Jpn J Exp Med 57:241-245
29. SM consomic mice. Exp Anim 58:357-361
30. Wang X, Paigen B (2005a) Genome-wide search for new genes controlling plasma lipid concentrations in mice and humans. Curr Opin Lipidol 16:127-137
31. Wang X, Paigen B (2005b) Genetics of variation in HDL cholesterol in humans and mice. Circ Res 96:27-42