Gut bacterial translocation contributes to microinflammation in experimental uremia

Digestive Diseases and Sciences

Volumn 57, Issue 11, 2012, Pages 2856-2862

  Wang, Feiqian ^a   Zhang, Pan ^a   Jiang, Hongli ^a   Cheng, Shaoli ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Bacterial translocation; Gut; Microbiome dysbiosis; Microinflammation; Uremia

Indexed keywords

BACTERIAL DNA; C REACTIVE PROTEIN; CREATININE; INTERLEUKIN 6; RNA 16S;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL TRANSLOCATION; BACTEROIDETES; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FIRMICUTES; INTESTINE FLORA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEOBACTERIA; PYROSEQUENCING; RAT; UREMIA;

ANIMALS; BACTERIAL TRANSLOCATION; C-REACTIVE PROTEIN; CHI-SQUARE DISTRIBUTION; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERLEUKIN-6; INTESTINAL MUCOSA; MALE; NEPHELOMETRY AND TURBIDIMETRY; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; STATISTICS, NONPARAMETRIC; UREMIA;

EID: 84871611055     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2242-0     Document Type: Article

References (33)

1. Tascilar N, Irkorucu O, Tascilar O, et al. Bacterial translocation in experimental stroke: what happens to the gut barrier? Bratisl Med J. 2010;111:194-199.
2. Magnotti LJ, Deitch EA. Burns, bacterial translocation, gut barrier function, and failure. J Burn Care Res. 2005;26:383-391.
3. van Minnen LP, Timmerman HM, Lutgendorff F, et al. Modification of intestinal flora with multispecies probiotics reduces bacterial translocation and improves clinical course in a rat model of acute pancreatitis. Surgery. 2007;141:470-480.
4. Wiest R, Garcia-Tsao G. Bacterial translocation (BT) in cirrhosis. Hepatology. 2005;41:422-433.
5. Schindler R. Causes and therapy of microinflammation in renal failure. Nephrol Dial Transpl. 2004;19:34-40.
6. Arici M, Walls J. End-stage renal disease, atherosclerosis, and cardiovascular mortality: is C-reactive protein the missing link? Kidney Int. 2001;59:407-414.
7. Chacaltana A, Velarde H, Espinoza J. Endoscopic lesions in the upper digestive tract in patients with terminal chronic renal insufficiency. Rev Gastroenterol Peru. 2007;27:246-252.
8. Kang J. The gastrointestinal tract in uremia. Dig Dis Sci. 1993;38:257-268.
9. Hirako M, Kamiya T, Misu N, et al. Impaired gastric motility and its relationship to gastrointestinal symptoms in patients with chronic renal failure. J Gastroenterol. 2005;40:1116-1122.
10. Magnusson M, Magnusson K, Sundqvist T, Denneberg T. Impaired intestinal barrier function measured by differently sized polyethylene glycols in patients with chronic renal failure. Gut. 1991;32:754-759.
11. Vaziri ND, Yuan J, Rahimi A, Ni Z, Said H, Subramanian VS. Disintegration of colonic epithelial tight junction in uremia: a likely cause of CKD-associated inflammation Nephrology Dialysis Transplantation. 2011;0:1-8.
12. Strid H, Simrén M, Stotzer PO, Ringstrm G, Abrahamsson H, Bjrnsson ES. Patients with chronic renal failure have abnormal small intestinal motility and a high prevalence of small intestinal bacterial overgrowth. Digestion. 2000;67:129-137.
13. Hauser AB, Stinghen AEM, Kato S, et al. Characteristics and causes of immune dysfunction related to uremia and dialysis. Periton Dialysis Int. 2008;28:S183-S187.
14. Bossola M, Sanguinetti M, Scribano D, et al. Circulating bacterial-derived DNA fragments and markers of inflammation in chronic hemodialysis patients. Clin J Am Soc Nephrol. 2009;4:379-385.
15. Naaber P, Smidt I, Tamme K, et al. Translocation of indigenous microflora in an experimental model of sepsis. J Med Microbiol. 2000;49:431-439.
16. Magnusson M, Magnusson K, Denneberg T. Impaired gut barrier in experimental chronic uremic rats. Mineral Electrolyte Metabolism. 1992;18:288.
17. de Almeida Duarte JB, de Aguilar-Nascimento JE, Nascimento M, Nochi RJ. Bacterial translocation in experimental uremia. Urol Res. 2004;32:266-270.
18. Sviglerova JK, Nalos L, Tonar Z, Rajdl D, Stengl M. Cardiovascular Parameters in Rat Model of Chronic Renal Failure Induced by Subtotal Nephrectomy. Physiol Res. 2010;59:S81-S88.
19. Perez-Paramo M, Munoz J, Albillos A, et al. Effect of propranolol on the factors promoting bacterial translocation in cirrhotic rats with ascites. Hepatology. 2000;31:43-48.
20. McKenna P, Hoffmann C, Minkah N, et al. The macaque gut microbiome in health, lentiviral infection, and chronic enterocolitis. PLoS Pathog. 2008;4:e20.
21. Suchodolski J, Dowd S, Westermarck E, et al. The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. BMC Microbiol. 2009;9:210.
22. Frances R, Benlloch S, Zapater P, et al. A sequential study of serum bacterial DNA in patients with advanced cirrhosis and ascites. Hepatology. 2004;39:484-491.
23. Steffen EK, Berg RD, Deitch EA. Comparison of translocation rates of various indigenous bacteria from the gastrointestinal tract to the mesenteric lymph node. J Infect Dis. 1988;157:1032-1038.
24. Ljungdahl M, Lundholm M, Katouli M, Rasmussen I, Engstrand L, Haglund U. Bacterial translocation in experimental shock is dependent on the strains in the intestinal flora. Scand J Gastroenterol. 2000;35:389-397.
25. Zhang SC, Wang W, Ren WY, He BM, Zhou K, Zhu WN. Effect of cisapride on intestinal bacterial and endotoxin translocation in cirrhosis. World J Gastroenterol. 2003;9:534-538.
26. Wenzl HH, Schimpl G, Feierl G, Steinwender G. Time course of spontaneous bacterial translocation from gastrointestinal tract and its relationship to intestinal microflora in conventionally reared infant rats. Digest Dis Sci. 2001;46:1120-1126.
27. Wells C. Relationship between intestinal microecology and the translocation of intestinal bacteria. Anton Leeu Int J G. 1990;58:87-93.
28. Mainous MR, Tso P, Berg RD, Deitch EA. Studies of the route, magnitude, and time course of bacterial translocation in a model of systemic inflammation. Arch Surg. 1991;126:33-37.
29. Berg RD. Bacterial translocation from the gastrointestinal tract. Trends Microbiol. 1995;3:149-154.
30. Nikitenko V, Stadnikov A, Kopylov V. Bacterial translocation from the gastrointestinal tract in healthy and injured rats. J Wound Care. 2011;20:114-122.
31. MacFie J. Current status of bacterial translocation as a cause of surgical sepsis. Br Med Bull. 2004;71:1-11.
32. Hersh D, Weiss J, Zychlinsky A. How bacteria initiate inflammation: aspects of the emerging story. Curr Opin Microbiol. 1998;1:43-48.
33. Zychlinsky A, Sansonetti PJ. Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death? Trends Microbiol. 1997;5:201-204.