Non-lesional white matter changes in pediatric multiple sclerosis and monophasic demyelinating disorders

Multiple Sclerosis Journal

Volumn 18, Issue 12, 2012, Pages 1754-1759

  Tillema, J M ^a   Leach, J ^b   Pirko, I ^a  

^a MAYO CLINIC   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

acute disseminated encephalomyelitis; MRI; multiple sclerosis; Pediatric

Indexed keywords

BETA1A INTERFERON; CORTICOSTEROID; GLATIRAMER;

ACUTE DISSEMINATED ENCEPHALOMYELITIS; ADOLESCENT; ARTICLE; CAPSULA INTERNA; CHILD; CHILDHOOD; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS CALLOSUM; DEMYELINATING DISEASE; DIFFUSION TENSOR IMAGING; FEMALE; FRACTIONAL ANISOTROPY; HUMAN; MALE; MULTIPLE SCLEROSIS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; ONSET AGE; PRESCHOOL CHILD; RETROSPECTIVE STUDY; SCHOOL CHILD; WHITE MATTER; WHITE MATTER LESION;

EID: 84871604756     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458512447527     Document Type: Article

References (29)

1. Mikaeloff Y, Adamsbaum C, Husson B, et al. MRI prognostic factors for relapse after acute CNS inflammatory demyelination in childhood. Brain. 2004 ; 127: 1942-1947
2. Mikaeloff Y, Caridade G, Assi S, et al. Prognostic factors for early severity in a childhood multiple sclerosis cohort. Pediatrics. 2006 ; 118: 1133-1139
3. Neuteboom RF, Boon M, Catsman Berrevoets CE, et al. Prognostic factors after a first attack of inflammatory CNS demyelination in children. Neurology. 2008 ; 71: 967-973
4. Neuteboom RF, Ketelslegers IA, Boon M, et al. Barkhof magnetic resonance imaging criteria predict early relapse in pediatric multiple sclerosis. Pediatr Neurol. 2010 ; 42: 53-55
5. Krupp LB, Banwell B, Tenembaum S. Consensus definitions proposed for pediatric multiple sclerosis and related disorders. Neurology. 2007 ; 68: S7 - S12
6. Callen DJ, Shroff MM, Branson HM, et al. Role of MRI in the differentiation of ADEM from MS in children. Neurology. 2009 ; 72: 968-973
7. Callen DJ, Shroff MM, Branson HM, et al. MRI in the diagnosis of pediatric multiple sclerosis. Neurology. 2009 ; 72: 961-967
8. Allen IV, McQuaid S, Mirakhur M, et al. Pathological abnormalities in the normal-appearing white matter in multiple sclerosis. Neurol Sci. 2001 ; 22: 141-144
9. Bammer R, Augustin M, Strasser-Fuchs S, et al. Magnetic resonance diffusion tensor imaging for characterizing diffuse and focal white matter abnormalities in multiple sclerosis. Magn Reson Med. 2000 ; 44: 583-591
10. Ciccarelli O, Werring DJ, Wheeler-Kingshott CA, et al. Investigation of MS normal-appearing brain using diffusion tensor MRI with clinical correlations. Neurology. 2001 ; 56: 926-933
11. Rovaris M, Gass A, Bammer R, et al. Diffusion MRI in multiple sclerosis. Neurology. 2005 ; 65: 1526-1532
12. Roosendaal SD, Geurts JJ, Vrenken H, et al. Regional DTI differences in multiple sclerosis patients. Neuroimage. 2009 ; 44: 1397-1403
13. Tortorella P, Rocca MA, Mezzapesa DM, et al. MRI quantification of gray and white matter damage in patients with early-onset multiple sclerosis. J Neurol. 2006 ; 253: 903-907
14. Vishwas MS, Chitnis T, Pienaar R, et al. Tract-based analysis of callosal, projection, and association pathways in pediatric patients with multiple sclerosis: a preliminary study. Am J Neuroradiol. 2010 2009 ;:
15. Absinta M, Rocca MA, Moiola L, et al. Brain macro- and microscopic damage in patients with paediatric MS. J Neurol Neurosurg Psychiatry. 2010 ; 81: 1357-1362
16. Raz E, Cercignani M, Sbardella E, et al. Gray- and white-matter changes 1 year after first clinical episode of multiple sclerosis: MR imaging. Radiology. 2010 ; 257 (2). 448-454
17. Naismith RT, Xu J, Tutlam NT, et al. Disability in optic neuritis correlates with diffusion tensor-derived directional diffusivities. Neurology. 2009 ; 72: 589-594
18. Jiang H, van Zijl PC, Kim J, et al. DtiStudio: resource program for diffusion tensor computation and fiber bundle tracking. Comput Methods Programs Biomed. 2006 ; 81: 106-116
19. Woods RP, Grafton ST, Holmes CJ, et al. Automated image registration: I. General methods and intrasubject, intramodality validation. J Comput Assist Tomogr. 1998 ; 22: 139-152
20. Pierpaoli C, Jezzard P, Basser PJ, et al. Diffusion tensor MR imaging of the human brain. Radiology. 1996 ; 201: 637-648
21. Song SK, Yoshino J, Le TQ, et al. Demyelination increases radial diffusivity in corpus callosum of mouse brain. Neuroimage. 2005 ; 26: 132-140
22. Song SK, Sun SW, Ju WK, et al. Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia. Neuroimage. 2003 ; 20: 1714-1722
23. Kern KC, Sarcona J, Montag M, et al. Corpus callosal diffusivity predicts motor impairment in relapsing-remitting multiple sclerosis: a TBSS and tractography study. Neuroimage. 2011 ; 55: 1169-1177
24. Concha L, Gross DW, Wheatley BM, Beaulieu C. Diffusion tensor imaging of time-dependent axonal and myelin degradation after corpus callosotomy in epilepsy patients. Neuroimage. 2006 ; 32 (3). 1090-1099
25. van de Looij Y, Mauconduit F, Beaumont M, et al. Diffusion tensor imaging of diffuse axonal injury in a rat brain trauma model. NMR Biomed. 2012 ; 25: 93-103
26. Kim JH, Budde MD, Liang HF, et al. Detecting axon damage in spinal cord from a mouse model of multiple sclerosis. Neurobiol Dis. 2006 ; 21: 626-632
27. Preziosa P, Rocca MA, Mesaros S, et al. Intrinsic damage to the major white matter tracts in patients with different clinical phenotypes of multiple sclerosis: a voxelwise diffusion-tensor MR study. Radiology. 2011 ; 260: 541-550
28. Klawiter EC, Schmidt RE, Trinkaus K, et al. Radial diffusivity predicts demyelination in ex vivo multiple sclerosis spinal cords. Neuroimage. 2011 ; 55: 1454-1460
29. Gallo A, Rovaris M, Riva R, et al. Diffusion-tensor magnetic resonance imaging detects normal-appearing white matter damage unrelated to short-term disease activity in patients at the earliest clinical stage of multiple sclerosis. Arch Neurol. 2005 ; 62: 803-808