5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A1 receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions

Molecules

Volumn 17, Issue 12, 2012, Pages 13712-13726

  Luongo, Livio ^a   Petrelli, Riccardo ^b   Gatta, Luisa ^a   Giordano, Catia ^a   Guida, Francesca ^a   Vita, Patrizia ^b   Franchetti, Palmarisa ^b   Grifantini, Mario ^b   De Novellis, Vito ^a   Cappellacci, Loredana ^b   Maione, Sabatino ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF CAMERINO   (Italy)

Author keywords

A1 adenosine receptor; Allodynia; Glia; Neuropathic pain

Indexed keywords

1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; DRUG DERIVATIVE; N(6) (2 ENDO NORBORNYL)ADENOSINE; N(6)-(2-ENDO-NORBORNYL)ADENOSINE; NORBORNANE DERIVATIVE; XANTHINE DERIVATIVE;

ANIMAL; ARTICLE; CARDIOVASCULAR SYSTEM; DRUG EFFECT; GLIA; HUMAN; HYPERALGESIA; INJURY; METABOLISM; MICROGLIA; MOTOR ACTIVITY; MOUSE; NEURALGIA; PATHOLOGY; SCIATIC NERVE;

ADENOSINE; ADENOSINE A1 RECEPTOR AGONISTS; ANIMALS; CARDIOVASCULAR SYSTEM; HUMANS; HYPERALGESIA; MICE; MICROGLIA; MOTOR ACTIVITY; NEURALGIA; NEUROGLIA; NORBORNANES; RECEPTOR, ADENOSINE A1; SCIATIC NERVE; XANTHINES;

EID: 84871587889     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules171213712     Document Type: Article

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