Efficient large-scale synthesis of a 2,4,5-triarylimidazoline MDM2 antagonist

Organic Process Research and Development

Volumn 16, Issue 12, 2012, Pages 1940-1946

  Shu, Lianhe ^a   Gu, Chen ^a   Dong, Yan ^a   Brinkman, Robert ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPHORSULFONIC ACID; CARBAMOYL CHLORIDES; CHIRAL RESOLUTIONS; IMIDAZOLINES; LARGE SCALE SYNTHESIS; NICOTINIC ACID; PHOSGENATION; SIDE-CHAINS;

CHLORINE COMPOUNDS;

STEREOCHEMISTRY;

EID: 84871586215     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op300294g     Document Type: Article

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