Multivalent pseudopeptides targeting cell surface nucleoproteins inhibit cancer cell invasion through tissue inhibitor of metalloproteinases 3 (TIMP-3) release

Journal of Biological Chemistry

Volumn 287, Issue 52, 2012, Pages 43685-43693

  Destouches, Damien ^a   Huet, Eric ^a   Sader, Maha ^a   Frechault, Sophie ^a   Carpentier, Gilles ^a   Ayoul, Florie ^a   Briand, Jean Paul ^b   Menashi, Suzanne ^a   Courty, José ^a  

^a Université Paris Est Créteil   (France)

^b INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ANTICANCER DRUG; BOYDEN CHAMBER; CANCER CELLS; CELL CULTURE MEDIUMS; CELL INVASION; CELL SURFACES; EXTRACELLULAR MATRICES; INHIBITORY EFFECT; MATRIX METALLOPROTEINASES; MELANOMA CELLS; METALLOPROTEINASES; MRNA EXPRESSION; NUCLEOLIN; NUCLEOPHOSMIN; PSEUDO-PEPTIDE; SIRNA SILENCING; SULFATED GLYCOSAMINOGLYCANS; SYNTHETIC LIGANDS; TISSUE INHIBITOR; TRANSGENIC MICE; TUMOR CELL INVASION; TUMOR GROWTH;

BIOCHEMISTRY; CELL CULTURE; DERMATOLOGY; ENZYME INHIBITION; LEAD COMPOUNDS; NUCLEIC ACIDS; ONCOLOGY; PATHOLOGY; TUMORS;

CELL MEMBRANES;

GLYCOSAMINOGLYCAN POLYSULFATE; MATRIX METALLOPROTEINASE; MESSENGER RNA; NUCANT 6L PEPTIDE; NUCLEOPROTEIN; PSEUDOPEPTIDE; SMALL INTERFERING RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 3; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL INVASION; CELL SURFACE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; ENZYME INHIBITION; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; TARGET CELL; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEAD; MICE; MICE, TRANSGENIC; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEOPLASMS; PEPTIDES; RNA, MESSENGER; RNA, NEOPLASM; TISSUE INHIBITOR OF METALLOPROTEINASE-3;

MUS MUSCULUS;

EID: 84871547567     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.380402     Document Type: Article

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