Mild Electrical Pulse Current Stimulation Upregulates S100A4 and Promotes Cardiogenesis in MSC and Cardiac Myocytes Coculture Monolayer

Cell Biochemistry and Biophysics

Volumn 65, Issue 1, 2013, Pages 43-55

  Wen, Lei ^a   Zhang, Changhai ^a   Nong, Yaoming ^a   Yao, Qing ^a   Song, Zhiyuan ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cardiac myocytes; Cardiogenesis; Cx43; Electrical pulse current stimulation; MEF2C; Mesenchymal stem cell; S100A4; Troponin T

Indexed keywords

RATTUS;

EID: 84871520119     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-012-9402-x     Document Type: Article

References (31)

1. Stary, M., Schneider, M., Sheikh, S. P., & Weitzer, G. (2006). Parietal endoderm secreted S100A4 promotes early cardiomyogenesis in embryoid bodies. Biochemical and Biophysical Research Communications, 343, 555-563.
2. Schneider, M., Kostin, S., Strøm, C. C., et al. (2007). S100A4 is upregulated in injured myocardium and promotes growth and survival of cardiac myocytes. Cardiovascular Research, 75, 40-50.
3. Zhao, M., Song, B., Pu, J., et al. (2006). Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN. Nature, 442, 457-460.
4. Thawer, H. A., & Houghton, P. E. (2001). Effects of electrical stimulation on the histological properties of wounds in diabetic mice. Wound Repair and Regeneration, 9, 107-115.
5. Tsai, M. T., Li, W. J., Tuan, R. S., et al. (2009). Modulation of osteogenesis in human mesenchymal stem cells by specific pulsed electromagnetic field stimulation. Journal of Orthopaedic Research, 27, 1169-1174.
6. Borgens, R. B., Vanable, J. W., & Jaffe, L. F. (1977). Bioelectricity and regeneration: Large currents leave the stumps of regenerating newt limbs. Proceedings of the National Academy of Sciences, 74, 4528-4532.
7. Berger, H. J., Prasad, S. K., Davidoff, A. J., et al. (1994). Continual electric field stimulation preserves contractile function of adult ventricular myocytes in primary culture. American Journal of Physiology, 266, 341-349.
8. Radisic, M., Park, H., Shing, H., et al. (2004). Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds. Proceedings of the National Academy of Sciences, 101, 18129-18134.
9. Pittenger, M. F., & Martin, B. J. (2004). Mesenchymal stem cells and their potential as cardiac therapeutics. Circulation Research, 95, 9-20.
10. Orlic, D., Hill, J. M., & Arai, A. E. (2002). Stem cells for myocardial regeneration. Circulation Research, 91, 1092-1102.
11. Shake, J. G., Gruber, P. J., Baumgartne, W. A., et al. (2002). Mesenchymal stem cell implantation in a swine myocardial infarct model: Engraftment and functional effects. The Annals of Thoracic Surgery, 73, 1919-1926.
12. Boomsma, R. A., & Geenen, D. L. (2012). Mesenchymal stem cells secrete multiple cytokines that promote angiogenesis and have contrasting effects on chemotaxis and apoptosis. PLoS One, 7, e35685.
13. Plotnikov, A. N., Shlapakova, I., Szabolcs, M. J., et al. (2007). Xenografted adult human mesenchymal stem cells provide a platform for sustained biological pacemaker function in canine heart. Circulation, 116, 706-713.
14. Potapova, I., Plotnikov, A., Lu, Z., et al. (2004). Human mesenchymal stem cells as a gene delivery system to create cardiac pacemakers. Circulation Research, 94, 952-959.
15. Takano, H., Ohtsuka, M., Akazawa, H., et al. (2003). Pleiotropic effects of cytokines on acute myocardial infarction: G-CSF as a novel therapy for acute myocardial infarction. Current Pharmaceutical Design, 9, 1121-1127.
16. Orlic, D., Kajstura, J., Chimenti, S., et al. (2001). Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proceedings of the National academy of Sciences of the United States of America, 98, 10344-10349.
17. Cooper, M. S. (1995). Membrane potential perturbations induced in tissue cells by pulsed electric fields. Bioelectromagnetics, 16, 255-262.
18. Grayson, W. L., Martens, T. P., Eng, G. M., et al. (2009). Biomimetic approach to tissue engineering. Seminars in Cell & Developmental Biology, 20, 665-673.
19. Soleimani, M., & Nadri, S. (2009). A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow. Nature Protocols, 4, 102-106.
20. Jun, C., Zhihui, Z., Lu, W., et al. (2012). Canine bone marrow mesenchymal stromal cells with lentiviral mHCN4 gene transfer create cardiac pacemakers. Cytotherapy, 14, 529-539.
21. Ieda, M., Fu, J. D., Delgado-Olguin, P., et al. (2010). Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell, 142, 375-386.
22. Ambartsumian, N., Klingelhöfer, J., Grigorian, M., et al. (2001). The metastasis-associated Mts1 (S100A4) protein could act as an angiogenic factor. Oncogene, 20, 4685.
23. Semov, A., Moreno, M. J., Onichtchenko, A., et al. (2005). Metastasis-associated protein S100A4 induces angiogenesis through interaction with annexin II and accelerated plasmin formation. Journal of Biological Chemistry, 280, 20833-20841.
24. Zeisberg, E. M., & Kalluri, R. (2010). Origins of cardiac fibroblasts. Circulation Research, 107, 1304-1312.
25. Hatzistergos, K. E., Quevedo, H., Oskouei, B. N., et al. (2010). Bone marrow mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiation novelty and significance. Circulation Research, 107, 913-922.
26. Martherus, R. S. R. M., Vanherle, S. J. V., Timmer, E. D. J., et al. (2010). Electrical signals affect the cardiomyocyte transcriptome independently of contraction. Physiological Genomics, 42, 283-289.
27. Filatov, V., Katrukha, A., Bulargina, T., et al. (1999). Troponin: structure, properties, and mechanism of functioning. Biochemistry c/c of Biokhimia, 64, 969-985.
28. Ohtsuki, I. (1999). Calcium ion regulation of muscle contraction: The regulatory role of troponin T. Molecular and Cellular Biochemistry, 190, 33-38.
29. Chang, M. G., Tung, L., Sekar, R. B., et al. (2006). Proarrhythmic potential of mesenchymal stem cell transplantation revealed in an in vitro coculture model. Circulation, 113, 1832-1841.
30. Danik, S. B., Rosner, G., Lader, J., et al. (2008). Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts. The Journal of the federatIon of American Societies for Experimental Biology, 22, 1204-1212.
31. Wang, D., Shen, W., Zhang, F., et al. (2010). Connexin43 promotes survival of mesenchymal stem cells in ischaemic heart. Cell Biology International, 34, 415-423.