-
1
-
-
61449095573
-
Leptin at 14 y of age: an ongoing story
-
Friedman JM. Leptin at 14 y of age: an ongoing story. Am J Clin Nutr 2009; 89: 973S-979S.
-
(2009)
Am J Clin Nutr
, vol.89
-
-
Friedman, J.M.1
-
2
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
3
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
Chehab FF, Lim ME, Lu R. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet 1996; 12: 318-320.
-
(1996)
Nat Genet
, vol.12
, pp. 318-320
-
-
Chehab, F.F.1
Lim, M.E.2
Lu, R.3
-
4
-
-
33645841079
-
Leptin is required for uncoupling protein-1-independent thermogenesis during cold stress
-
Ukropec J, Anunciado RV, Ravussin Y, Kozak LP. Leptin is required for uncoupling protein-1-independent thermogenesis during cold stress. Endocrinology 2006; 147: 2468-2480.
-
(2006)
Endocrinology
, vol.147
, pp. 2468-2480
-
-
Ukropec, J.1
Anunciado, R.V.2
Ravussin, Y.3
Kozak, L.P.4
-
5
-
-
33750311697
-
Impairment of dendritic cell functionality and steady-state number in obese mice
-
Macia L, Delacre M, Abboud G, Ouk TS, Delanoye A, Verwaerde C, Saule P, Wolowczuk I. Impairment of dendritic cell functionality and steady-state number in obese mice. J Immunol 2006; 177: 5997-6006.
-
(2006)
J Immunol
, vol.177
, pp. 5997-6006
-
-
Macia, L.1
Delacre, M.2
Abboud, G.3
Ouk, T.S.4
Delanoye, A.5
Verwaerde, C.6
Saule, P.7
Wolowczuk, I.8
-
6
-
-
0141737573
-
Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass
-
Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, Beil FT, Shen J, Vinson C, Rueger JM, Karsenty G. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 2000; 100: 197-207.
-
(2000)
Cell
, vol.100
, pp. 197-207
-
-
Ducy, P.1
Amling, M.2
Takeda, S.3
Priemel, M.4
Schilling, A.F.5
Beil, F.T.6
Shen, J.7
Vinson, C.8
Rueger, J.M.9
Karsenty, G.10
-
7
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ, Lakey ND, Culpepper J, Moore KJ, Breitbart RE, Duyk GM, Tepper RI, Morgenstern JP. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996; 84: 491-495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
8
-
-
77955236781
-
Central leptin signalling: beyond the arcuate nucleus
-
Jovanovic Z, Yeo GS. Central leptin signalling: beyond the arcuate nucleus. Auton Neurosci 2010; 156: 8-14.
-
(2010)
Auton Neurosci
, vol.156
, pp. 8-14
-
-
Jovanovic, Z.1
Yeo, G.S.2
-
9
-
-
0031766722
-
Hyperphagia and weight gain after gold-thioglucose: relation to hypothalamic neuropeptide Y and proopiomelanocortin
-
Bergen HT, Mizuno TM, Taylor J, Mobbs CV. Hyperphagia and weight gain after gold-thioglucose: relation to hypothalamic neuropeptide Y and proopiomelanocortin. Endocrinology 1998; 139: 4483-4488.
-
(1998)
Endocrinology
, vol.139
, pp. 4483-4488
-
-
Bergen, H.T.1
Mizuno, T.M.2
Taylor, J.3
Mobbs, C.V.4
-
10
-
-
0036847619
-
Leptin regulates bone formation via the sympathetic nervous system
-
Takeda S, Elefteriou F, Levasseur R, Liu X, Zhao L, Parker KL, Armstrong D, Ducy P, Karsenty G. Leptin regulates bone formation via the sympathetic nervous system. Cell 2002; 111: 305-317.
-
(2002)
Cell
, vol.111
, pp. 305-317
-
-
Takeda, S.1
Elefteriou, F.2
Levasseur, R.3
Liu, X.4
Zhao, L.5
Parker, K.L.6
Armstrong, D.7
Ducy, P.8
Karsenty, G.9
-
11
-
-
69449083603
-
A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure
-
Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G. A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell 2009; 138: 976-989.
-
(2009)
Cell
, vol.138
, pp. 976-989
-
-
Yadav, V.K.1
Oury, F.2
Suda, N.3
Liu, Z.W.4
Gao, X.B.5
Confavreux, C.6
Klemenhagen, K.C.7
Tanaka, K.F.8
Gingrich, J.A.9
Guo, X.E.10
Tecott, L.H.11
Mann, J.J.12
Hen, R.13
Horvath, T.L.14
Karsenty, G.15
-
12
-
-
58149395696
-
Novel leptin-regulated genes revealed by transcriptional profiling of the hypothalamic paraventricular nucleus
-
Tung YC, Ma M, Piper S, Coll A, O'Rahilly S, Yeo GS. Novel leptin-regulated genes revealed by transcriptional profiling of the hypothalamic paraventricular nucleus. J Neurosci 2008; 28: 12419-12426.
-
(2008)
J Neurosci
, vol.28
, pp. 12419-12426
-
-
Tung, Y.C.1
Ma, M.2
Piper, S.3
Coll, A.4
O'Rahilly, S.5
Yeo, G.S.6
-
13
-
-
77954694568
-
Identification of the global transcriptomic response of the hypothalamic arcuate nucleus to fasting and leptin
-
Jovanovic Z, Tung YC, Lam BY, O'Rahilly S, Yeo GS. Identification of the global transcriptomic response of the hypothalamic arcuate nucleus to fasting and leptin. J Neuroendocrinol 2010; 22: 915-925.
-
(2010)
J Neuroendocrinol
, vol.22
, pp. 915-925
-
-
Jovanovic, Z.1
Tung, Y.C.2
Lam, B.Y.3
O'Rahilly, S.4
Yeo, G.S.5
-
14
-
-
70349308376
-
Transthyretin: the servant of many masters
-
Buxbaum JN, Reixach N. Transthyretin: the servant of many masters. Cell Mol Life Sci 2009; 66: 3095-3101.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 3095-3101
-
-
Buxbaum, J.N.1
Reixach, N.2
-
15
-
-
0024579185
-
Transthyretin immunoreactivity in human and porcine liver, choroid plexus, and pancreatic islets
-
Jacobsson B, Collins VP, Grimelius L, Pettersson T, Sandstedt B, Carlström A. Transthyretin immunoreactivity in human and porcine liver, choroid plexus, and pancreatic islets. J Histochem Cytochem 1989; 37: 31-37.
-
(1989)
J Histochem Cytochem
, vol.37
, pp. 31-37
-
-
Jacobsson, B.1
Collins, V.P.2
Grimelius, L.3
Pettersson, T.4
Sandstedt, B.5
Carlström, A.6
-
16
-
-
0027512354
-
Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone
-
Episkopou V, Maeda S, Nishiguchi S, Shimada K, Gaitanaris GA, Gottesman ME, Robertson EJ. Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone. Proc Natl Acad Sci USA 1993; 90: 2375-2379.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2375-2379
-
-
Episkopou, V.1
Maeda, S.2
Nishiguchi, S.3
Shimada, K.4
Gaitanaris, G.A.5
Gottesman, M.E.6
Robertson, E.J.7
-
17
-
-
22844447647
-
Transthyretin-related familial amyloidotic polyneuropathy
-
Ando Y, Nakamura M, Araki S. Transthyretin-related familial amyloidotic polyneuropathy. Arch Neurol 2005; 62: 1057-1062.
-
(2005)
Arch Neurol
, vol.62
, pp. 1057-1062
-
-
Ando, Y.1
Nakamura, M.2
Araki, S.3
-
18
-
-
40649096849
-
Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity
-
Buxbaum JN, Ye Z, Reixach N, Friske L, Levy C, Das P, Golde T, Masliah E, Roberts AR, Bartfai T. Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Proc Natl Acad Sci USA 2008; 105: 2681-2686.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2681-2686
-
-
Buxbaum, J.N.1
Ye, Z.2
Reixach, N.3
Friske, L.4
Levy, C.5
Das, P.6
Golde, T.7
Masliah, E.8
Roberts, A.R.9
Bartfai, T.10
-
19
-
-
1442299424
-
Transthyretin is involved in depression-like behaviour and exploratory activity
-
Sousa JC, Grandela C, Fernández-Ruiz J, de Miguel R, de Sousa L, Magalhães AI, Saraiva MJ, Sousa N, Palha JA. Transthyretin is involved in depression-like behaviour and exploratory activity. J Neurochem 2004; 88: 1052-1058.
-
(2004)
J Neurochem
, vol.88
, pp. 1052-1058
-
-
Sousa, J.C.1
Grandela, C.2
Fernández-Ruiz, J.3
de Miguel, R.4
de Sousa, L.5
Magalhães, A.I.6
Saraiva, M.J.7
Sousa, N.8
Palha, J.A.9
-
20
-
-
30744463914
-
Transthyretin knockouts are a new mouse model for increased neuropeptide Y
-
Nunes AF, Saraiva MJ, Sousa MM. Transthyretin knockouts are a new mouse model for increased neuropeptide Y. FASEB J 2006; 20: 166-168.
-
(2006)
FASEB J
, vol.20
, pp. 166-168
-
-
Nunes, A.F.1
Saraiva, M.J.2
Sousa, M.M.3
-
21
-
-
41649102414
-
Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice
-
Mody N, Graham TE, Tsuji Y, Yang Q, Kahn BB. Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice. Am J Physiol Endocrinol Metab 2008; 294: E785-E793.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Mody, N.1
Graham, T.E.2
Tsuji, Y.3
Yang, Q.4
Kahn, B.B.5
-
22
-
-
67349206201
-
Impaired gastric acidification negatively affects calcium homeostasis and bone mass
-
Schinke T, Schilling AF, Baranowsky A, Seitz S, Marshall RP, Linn T, Blaeker M, Huebner AK, Schulz A, Simon R, Gebauer M, Priemel M, Kornak U, Perkovic S, Barvencik F, Beil FT, Del Fattore A, Frattini A, Streichert T, Pueschel K, Villa A, Debatin KM, Rueger JM, Teti A, Zustin J, Sauter G, Amling M. Impaired gastric acidification negatively affects calcium homeostasis and bone mass. Nat Med 2009; 15: 674-681.
-
(2009)
Nat Med
, vol.15
, pp. 674-681
-
-
Schinke, T.1
Schilling, A.F.2
Baranowsky, A.3
Seitz, S.4
Marshall, R.P.5
Linn, T.6
Blaeker, M.7
Huebner, A.K.8
Schulz, A.9
Simon, R.10
Gebauer, M.11
Priemel, M.12
Kornak, U.13
Perkovic, S.14
Barvencik, F.15
Beil, F.T.16
Del Fattore, A.17
Frattini, A.18
Streichert, T.19
Pueschel, K.20
Villa, A.21
Debatin, K.M.22
Rueger, J.M.23
Teti, A.24
Zustin, J.25
Sauter, G.26
Amling, M.27
more..
-
23
-
-
77956408745
-
Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: modulation by diet-induced obesity
-
Bartelt A, Beil FT, Schinke T, Roeser K, Ruether W, Heeren J, Niemeier A. Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: modulation by diet-induced obesity. Bone 2010; 47: 736-745.
-
(2010)
Bone
, vol.47
, pp. 736-745
-
-
Bartelt, A.1
Beil, F.T.2
Schinke, T.3
Roeser, K.4
Ruether, W.5
Heeren, J.6
Niemeier, A.7
-
24
-
-
0018043076
-
Thyroid status of obese (ob/ob) mice and its relationship to adipose tissue metabolism
-
York DA, Otto W, Taylor TG. Thyroid status of obese (ob/ob) mice and its relationship to adipose tissue metabolism. Comp Biochem Physiol 1978; 59: 59-65.
-
(1978)
Comp Biochem Physiol
, vol.59
, pp. 59-65
-
-
York, D.A.1
Otto, W.2
Taylor, T.G.3
-
25
-
-
34547643226
-
The absence of transthyretin does not impair regulation of lipid and glucose metabolism
-
Marques F, Sousa JC, Oliveira P, Oliveira HC, Palha JA. The absence of transthyretin does not impair regulation of lipid and glucose metabolism. Horm Metab Res 2007; 39: 529-533.
-
(2007)
Horm Metab Res
, vol.39
, pp. 529-533
-
-
Marques, F.1
Sousa, J.C.2
Oliveira, P.3
Oliveira, H.C.4
Palha, J.A.5
-
26
-
-
73649127668
-
Neuropeptide Y expression and function during osteoblast differentiation - insights from transthyretin knockout mice
-
Nunes AF, Liz MA, Franquinho F, Teixeira L, Sousa V, Chenu C, Lamghari M, Sousa MM. Neuropeptide Y expression and function during osteoblast differentiation - insights from transthyretin knockout mice. FEBS J 2010; 277: 263-275.
-
(2010)
FEBS J
, vol.277
, pp. 263-275
-
-
Nunes, A.F.1
Liz, M.A.2
Franquinho, F.3
Teixeira, L.4
Sousa, V.5
Chenu, C.6
Lamghari, M.7
Sousa, M.M.8
-
27
-
-
22944434929
-
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
-
Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, Kotani K, Quadro L, Kahn BB. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 2005; 436: 356-362.
-
(2005)
Nature
, vol.436
, pp. 356-362
-
-
Yang, Q.1
Graham, T.E.2
Mody, N.3
Preitner, F.4
Peroni, O.D.5
Zabolotny, J.M.6
Kotani, K.7
Quadro, L.8
Kahn, B.B.9
-
28
-
-
33745095399
-
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects
-
Graham TE, Yang Q, Blüher M, Hammarstedt A, Ciaraldi TP, Henry RR, Wason CJ, Oberbach A, Jansson PA, Smith U, Kahn BB. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N Engl J Med 2006; 354: 2552-2563.
-
(2006)
N Engl J Med
, vol.354
, pp. 2552-2563
-
-
Graham, T.E.1
Yang, Q.2
Blüher, M.3
Hammarstedt, A.4
Ciaraldi, T.P.5
Henry, R.R.6
Wason, C.J.7
Oberbach, A.8
Jansson, P.A.9
Smith, U.10
Kahn, B.B.11
-
29
-
-
84861968652
-
Inverse association between serum free thyroxine levels and hepatic steatosis: results from the study of health in pomerania
-
Ittermann T, Haring R, Wallaschofski H, Baumeister SE, Nauck M, Dörr M, Lerch MM, Meyer Zu, Schwabedissen H, Rosskopf D, Völzke H. Inverse association between serum free thyroxine levels and hepatic steatosis: results from the study of health in pomerania. Thyroid 2012; 22: 568-74.
-
(2012)
Thyroid
, vol.22
, pp. 568-574
-
-
Ittermann, T.1
Haring, R.2
Wallaschofski, H.3
Baumeister, S.E.4
Nauck, M.5
Dörr, M.6
Lerch, M.M.7
Meyer, Z.8
Schwabedissen, H.9
Rosskopf, D.10
Völzke, H.11
-
30
-
-
0037006110
-
Vitamin A intake and hip fractures among postmenopausal women
-
Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002; 287: 47-54.
-
(2002)
JAMA
, vol.287
, pp. 47-54
-
-
Feskanich, D.1
Singh, V.2
Willett, W.C.3
Colditz, G.A.4
-
32
-
-
0033826264
-
Opposite effects of feeding a vitamin A-deficient diet and retinoic acid treatment on brown adipose tissue uncoupling protein 1 (UCP1), UCP2 and leptin expression
-
Bonet ML, Oliver J, Picó C, Felipe F, Ribot J, Cinti S, Palou A. Opposite effects of feeding a vitamin A-deficient diet and retinoic acid treatment on brown adipose tissue uncoupling protein 1 (UCP1), UCP2 and leptin expression. J Endocrinol 2000; 166: 511-517.
-
(2000)
J Endocrinol
, vol.166
, pp. 511-517
-
-
Bonet, M.L.1
Oliver, J.2
Picó, C.3
Felipe, F.4
Ribot, J.5
Cinti, S.6
Palou, A.7
-
33
-
-
0035432378
-
Changes of adiposity in response to vitamin A status correlate with changes of PPAR gamma 2 expression
-
Ribot J, Felipe F, Bonet ML, Palou A. Changes of adiposity in response to vitamin A status correlate with changes of PPAR gamma 2 expression. Obes Res 2001; 9: 500-509.
-
(2001)
Obes Res
, vol.9
, pp. 500-509
-
-
Ribot, J.1
Felipe, F.2
Bonet, M.L.3
Palou, A.4
-
34
-
-
4043094220
-
Retinoic acid receptor alpha dominant negative form causes steatohepatitis and liver tumors in transgenic mice
-
Yanagitani A, Yamada S, Yasui S, Shimomura T, Murai R, Murawaki Y, Hashiguchi K, Kanbe T, Saeki T, Ichiba M, Tanabe Y, Yoshida Y, Morino S, Kurimasa A, Usuda N, Yamazaki H, Kunisada T, Ito H, Murawaki Y, Shiota G. Retinoic acid receptor alpha dominant negative form causes steatohepatitis and liver tumors in transgenic mice. Hepatology 2004; 40: 366-375.
-
(2004)
Hepatology
, vol.40
, pp. 366-375
-
-
Yanagitani, A.1
Yamada, S.2
Yasui, S.3
Shimomura, T.4
Murai, R.5
Murawaki, Y.6
Hashiguchi, K.7
Kanbe, T.8
Saeki, T.9
Ichiba, M.10
Tanabe, Y.11
Yoshida, Y.12
Morino, S.13
Kurimasa, A.14
Usuda, N.15
Yamazaki, H.16
Kunisada, T.17
Ito, H.18
Murawaki, Y.19
Shiota, G.20
more..
-
35
-
-
34249074765
-
Altered lipid catabolism in the vitamin A deficient liver
-
Kang HW, Bhimidi GR, Odom DP, Brun PJ, Fernandez ML, McGrane MM. Altered lipid catabolism in the vitamin A deficient liver. Mol Cell Endocrinol 2007; 271: 18-27.
-
(2007)
Mol Cell Endocrinol
, vol.271
, pp. 18-27
-
-
Kang, H.W.1
Bhimidi, G.R.2
Odom, D.P.3
Brun, P.J.4
Fernandez, M.L.5
McGrane, M.M.6
|