메뉴 건너뛰기




Volumn 53, Issue 1, 2013, Pages 51-58

PTH (1-34), but not strontium ranelate counteract loss of trabecular thickness and bone strength in disuse osteopenic rats

Author keywords

Histomorphometry; Immobilization; Mechanics; PTH; Rat; Strontium ranelate

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ALKALINE PHOSPHATASE; PARATHYROID HORMONE[1-34]; STRONTIUM RANELATE;

EID: 84871503533     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2012.11.037     Document Type: Article
Times cited : (28)

References (39)
  • 1
    • 0034612094 scopus 로고    scopus 로고
    • Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts
    • Vico L., Collet P., Guignandon A., Lafage-Proust M.H., Thomas T., Rehaillia M., et al. Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts. Lancet 2000, 355:1607-1611.
    • (2000) Lancet , vol.355 , pp. 1607-1611
    • Vico, L.1    Collet, P.2    Guignandon, A.3    Lafage-Proust, M.H.4    Thomas, T.5    Rehaillia, M.6
  • 5
    • 0001590928 scopus 로고    scopus 로고
    • Overview: animal models of osteopenia and osteoporosis
    • Jee W.S., Yao W. Overview: animal models of osteopenia and osteoporosis. J Musculoskelet Neuronal Interact 2001, 1:193-207.
    • (2001) J Musculoskelet Neuronal Interact , vol.1 , pp. 193-207
    • Jee, W.S.1    Yao, W.2
  • 6
    • 0035141959 scopus 로고    scopus 로고
    • Texture analysis of X-ray radiographs is a more reliable descriptor of bone loss than mineral content in a rat model of localized disuse induced by the Clostridium botulinum toxin
    • Chappard D., Chennebault A., Moreau M., Legrand E., Audran M., Basle M.F. Texture analysis of X-ray radiographs is a more reliable descriptor of bone loss than mineral content in a rat model of localized disuse induced by the Clostridium botulinum toxin. Bone 2001, 28:72-79.
    • (2001) Bone , vol.28 , pp. 72-79
    • Chappard, D.1    Chennebault, A.2    Moreau, M.3    Legrand, E.4    Audran, M.5    Basle, M.F.6
  • 8
    • 0035837553 scopus 로고    scopus 로고
    • Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis
    • Neer R.M., Arnaud C.D., Zanchetta J.R., Prince R., Gaich G.A., Reginster J.Y., et al. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med 2001, 344:1434-1441.
    • (2001) N Engl J Med , vol.344 , pp. 1434-1441
    • Neer, R.M.1    Arnaud, C.D.2    Zanchetta, J.R.3    Prince, R.4    Gaich, G.A.5    Reginster, J.Y.6
  • 9
    • 0026584625 scopus 로고
    • Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone
    • Hock J.M., Gera I. Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone. J Bone Miner Res 1992, 7:65-72.
    • (1992) J Bone Miner Res , vol.7 , pp. 65-72
    • Hock, J.M.1    Gera, I.2
  • 11
    • 0028961558 scopus 로고
    • Human parathyroid hormone-(1-38) restores cancellous bone to the immobilized, osteopenic proximal tibial metaphysis in rats
    • Ma Y.F., Jee W.S., Ke H.Z., Lin B.Y., Liang X.G., Li M., et al. Human parathyroid hormone-(1-38) restores cancellous bone to the immobilized, osteopenic proximal tibial metaphysis in rats. J Bone Miner Res 1995, 10:496-505.
    • (1995) J Bone Miner Res , vol.10 , pp. 496-505
    • Ma, Y.F.1    Jee, W.S.2    Ke, H.Z.3    Lin, B.Y.4    Liang, X.G.5    Li, M.6
  • 12
    • 9144233479 scopus 로고    scopus 로고
    • The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis
    • Meunier P.J., Roux C., Seeman E., Ortolani S., Badurski J.E., Spector T.D., et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 2004, 350:459-468.
    • (2004) N Engl J Med , vol.350 , pp. 459-468
    • Meunier, P.J.1    Roux, C.2    Seeman, E.3    Ortolani, S.4    Badurski, J.E.5    Spector, T.D.6
  • 13
    • 45349090543 scopus 로고    scopus 로고
    • Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: results of a five-year, randomized, placebo-controlled trial
    • Reginster J.Y., Felsenberg D., Boonen S., Diez-Perez A., Rizzoli R., Brandi M.L., et al. Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: results of a five-year, randomized, placebo-controlled trial. Arthritis Rheum 2008, 58:1687-1695.
    • (2008) Arthritis Rheum , vol.58 , pp. 1687-1695
    • Reginster, J.Y.1    Felsenberg, D.2    Boonen, S.3    Diez-Perez, A.4    Rizzoli, R.5    Brandi, M.L.6
  • 14
    • 21044447888 scopus 로고    scopus 로고
    • Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study
    • Reginster J.Y., Seeman E., De Vernejoul M.C., Adami S., Compston J., Phenekos C., et al. Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study. J Clin Endocrinol Metab 2005, 90:2816-2822.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2816-2822
    • Reginster, J.Y.1    Seeman, E.2    De Vernejoul, M.C.3    Adami, S.4    Compston, J.5    Phenekos, C.6
  • 15
    • 31944442279 scopus 로고    scopus 로고
    • Strontium ranelate: a physiological approach for optimizing bone formation and resorption
    • Marie P.J. Strontium ranelate: a physiological approach for optimizing bone formation and resorption. Bone 2006, 38:S10-S14.
    • (2006) Bone , vol.38
    • Marie, P.J.1
  • 16
    • 17644382533 scopus 로고    scopus 로고
    • Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats
    • Ammann P., Shen V., Robin B., Mauras Y., Bonjour J.P., Rizzoli R. Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats. J Bone Miner Res 2004, 19:2012-2020.
    • (2004) J Bone Miner Res , vol.19 , pp. 2012-2020
    • Ammann, P.1    Shen, V.2    Robin, B.3    Mauras, Y.4    Bonjour, J.P.5    Rizzoli, R.6
  • 17
    • 0036068720 scopus 로고    scopus 로고
    • Long-term treatment with strontium ranelate increases vertebral bone mass without deleterious effect in mice
    • Delannoy P., Bazot D., Marie P.J. Long-term treatment with strontium ranelate increases vertebral bone mass without deleterious effect in mice. Metabolism 2002, 51:906-911.
    • (2002) Metabolism , vol.51 , pp. 906-911
    • Delannoy, P.1    Bazot, D.2    Marie, P.J.3
  • 18
    • 0042707618 scopus 로고    scopus 로고
    • S12911-2 reduces bone loss induced by short-term immobilization in rats
    • Hott M., Deloffre P., Tsouderos Y., Marie P.J. S12911-2 reduces bone loss induced by short-term immobilization in rats. Bone 2003, 33:115-123.
    • (2003) Bone , vol.33 , pp. 115-123
    • Hott, M.1    Deloffre, P.2    Tsouderos, Y.3    Marie, P.J.4
  • 19
    • 84862782255 scopus 로고    scopus 로고
    • Strontium ranelate prevents bone loss in a rat model of localized muscle paralysis
    • Sheng Z.F., Ma Y.L., Tong D., Fang D.Y., Liang Q.C., Liu L.H., et al. Strontium ranelate prevents bone loss in a rat model of localized muscle paralysis. Ann Biomed Eng 2012, 40:657-665.
    • (2012) Ann Biomed Eng , vol.40 , pp. 657-665
    • Sheng, Z.F.1    Ma, Y.L.2    Tong, D.3    Fang, D.Y.4    Liang, Q.C.5    Liu, L.H.6
  • 20
    • 0023915687 scopus 로고
    • Human parathyroid hormone-(1-34) increases bone mass in ovariectomized and orchidectomized rats
    • Hock J.M., Gera I., Fonseca J., Raisz L.G. Human parathyroid hormone-(1-34) increases bone mass in ovariectomized and orchidectomized rats. Endocrinology 1988, 122:2899-2904.
    • (1988) Endocrinology , vol.122 , pp. 2899-2904
    • Hock, J.M.1    Gera, I.2    Fonseca, J.3    Raisz, L.G.4
  • 21
    • 1642341604 scopus 로고    scopus 로고
    • Simvastatin treatment partially prevents ovariectomy-induced bone loss while increasing cortical bone formation
    • Oxlund H., Andreassen T.T. Simvastatin treatment partially prevents ovariectomy-induced bone loss while increasing cortical bone formation. Bone 2004, 34:609-618.
    • (2004) Bone , vol.34 , pp. 609-618
    • Oxlund, H.1    Andreassen, T.T.2
  • 22
    • 84985280160 scopus 로고
    • The efficiency of systematic sampling in stereology and its prediction
    • Gundersen H.J., Jensen E.B. The efficiency of systematic sampling in stereology and its prediction. J Microsc 1987, 147:229-263.
    • (1987) J Microsc , vol.147 , pp. 229-263
    • Gundersen, H.J.1    Jensen, E.B.2
  • 23
    • 18444365600 scopus 로고    scopus 로고
    • Stereological measures of trabecular bone structure: comparison of 3D micro computed tomography with 2D histological sections in human proximal tibial bone biopsies
    • Thomsen J.S., Laib A., Koller B., Prohaska S., Mosekilde L., Gowin W. Stereological measures of trabecular bone structure: comparison of 3D micro computed tomography with 2D histological sections in human proximal tibial bone biopsies. J Microsc 2005, 218:171-179.
    • (2005) J Microsc , vol.218 , pp. 171-179
    • Thomsen, J.S.1    Laib, A.2    Koller, B.3    Prohaska, S.4    Mosekilde, L.5    Gowin, W.6
  • 24
    • 19944432718 scopus 로고    scopus 로고
    • Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption
    • Karsdal M.A., Henriksen K., Sorensen M.G., Gram J., Schaller S., Dziegiel M.H., et al. Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption. Am J Pathol 2005, 166:467-476.
    • (2005) Am J Pathol , vol.166 , pp. 467-476
    • Karsdal, M.A.1    Henriksen, K.2    Sorensen, M.G.3    Gram, J.4    Schaller, S.5    Dziegiel, M.H.6
  • 25
    • 57249097079 scopus 로고    scopus 로고
    • Characterization of the bone phenotype in ClC-7-deficient mice
    • Neutzsky-Wulff A.V., Karsdal M.A., Henriksen K. Characterization of the bone phenotype in ClC-7-deficient mice. Calcif Tissue Int 2008, 83:425-437.
    • (2008) Calcif Tissue Int , vol.83 , pp. 425-437
    • Neutzsky-Wulff, A.V.1    Karsdal, M.A.2    Henriksen, K.3
  • 26
    • 0027489957 scopus 로고
    • Parathyroid hormone (1-34) and (1-84) stimulate cortical bone formation both from periosteum and endosteum
    • Oxlund H., Ejersted C., Andreassen T.T., Torring O., Nilsson M.H. Parathyroid hormone (1-34) and (1-84) stimulate cortical bone formation both from periosteum and endosteum. Calcif Tissue Int 1993, 53:394-399.
    • (1993) Calcif Tissue Int , vol.53 , pp. 394-399
    • Oxlund, H.1    Ejersted, C.2    Andreassen, T.T.3    Torring, O.4    Nilsson, M.H.5
  • 27
    • 0025896380 scopus 로고
    • The anabolic effects of human parathyroid hormone (hPTH) on rat vertebral body mass are also reflected in the quality of bone, assessed by biomechanical testing: a comparison study between hPTH-(1-34) and hPTH-(1-84)
    • Mosekilde L., Sogaard C.H., Danielsen C.C., Torring O. The anabolic effects of human parathyroid hormone (hPTH) on rat vertebral body mass are also reflected in the quality of bone, assessed by biomechanical testing: a comparison study between hPTH-(1-34) and hPTH-(1-84). Endocrinology 1991, 129:421-428.
    • (1991) Endocrinology , vol.129 , pp. 421-428
    • Mosekilde, L.1    Sogaard, C.H.2    Danielsen, C.C.3    Torring, O.4
  • 28
    • 0030730232 scopus 로고    scopus 로고
    • The effects of programmed administration of human parathyroid hormone fragment (1-34) on bone histomorphometry and serum chemistry in rats
    • Dobnig H., Turner R.T. The effects of programmed administration of human parathyroid hormone fragment (1-34) on bone histomorphometry and serum chemistry in rats. Endocrinology 1997, 138:4607-4612.
    • (1997) Endocrinology , vol.138 , pp. 4607-4612
    • Dobnig, H.1    Turner, R.T.2
  • 29
    • 34248577022 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of the anabolic effect of intermittent PTH
    • Jilka R.L. Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone 2007, 40:1434-1446.
    • (2007) Bone , vol.40 , pp. 1434-1446
    • Jilka, R.L.1
  • 30
    • 79955422720 scopus 로고    scopus 로고
    • Teriparatide [rhPTH (1-34)], but not strontium ranelate, demonstrated bone anabolic efficacy in mature, osteopenic, ovariectomized rats
    • Ma Y.L., Zeng Q.Q., Porras L.L., Harvey A., Moore T.L., Shelbourn T.L., et al. Teriparatide [rhPTH (1-34)], but not strontium ranelate, demonstrated bone anabolic efficacy in mature, osteopenic, ovariectomized rats. Endocrinology 2011, 152:1767-1778.
    • (2011) Endocrinology , vol.152 , pp. 1767-1778
    • Ma, Y.L.1    Zeng, Q.Q.2    Porras, L.L.3    Harvey, A.4    Moore, T.L.5    Shelbourn, T.L.6
  • 31
    • 0031734073 scopus 로고    scopus 로고
    • Programmed administration of parathyroid hormone increases bone formation and reduces bone loss in hindlimb-unloaded ovariectomized rats
    • Turner R.T., Evans G.L., Cavolina J.M., Halloran B., Morey-Holton E. Programmed administration of parathyroid hormone increases bone formation and reduces bone loss in hindlimb-unloaded ovariectomized rats. Endocrinology 1998, 139:4086-4091.
    • (1998) Endocrinology , vol.139 , pp. 4086-4091
    • Turner, R.T.1    Evans, G.L.2    Cavolina, J.M.3    Halloran, B.4    Morey-Holton, E.5
  • 32
    • 0033791137 scopus 로고    scopus 로고
    • The influence of combined parathyroid hormone and growth hormone treatment on cortical bone in aged ovariectomized rats
    • Andreassen T.T., Oxlund H. The influence of combined parathyroid hormone and growth hormone treatment on cortical bone in aged ovariectomized rats. J Bone Miner Res 2000, 15:2266-2275.
    • (2000) J Bone Miner Res , vol.15 , pp. 2266-2275
    • Andreassen, T.T.1    Oxlund, H.2
  • 33
    • 0029595236 scopus 로고
    • Parathyroid hormone (1-34) increases vertebral bone mass, compressive strength, and quality in old rats
    • Ejersted C., Andreassen T.T., Hauge E.M., Melsen F., Oxlund H. Parathyroid hormone (1-34) increases vertebral bone mass, compressive strength, and quality in old rats. Bone 1995, 17:507-511.
    • (1995) Bone , vol.17 , pp. 507-511
    • Ejersted, C.1    Andreassen, T.T.2    Hauge, E.M.3    Melsen, F.4    Oxlund, H.5
  • 34
    • 77955914535 scopus 로고    scopus 로고
    • In vivo anabolic effect of strontium on trabecular bone was associated with increased osteoblastogenesis of bone marrow stromal cells
    • Peng S., Liu X.S., Wang T., Li Z., Zhou G., Luk K.D., et al. In vivo anabolic effect of strontium on trabecular bone was associated with increased osteoblastogenesis of bone marrow stromal cells. J Orthop Res 2010, 28:1208-1214.
    • (2010) J Orthop Res , vol.28 , pp. 1208-1214
    • Peng, S.1    Liu, X.S.2    Wang, T.3    Li, Z.4    Zhou, G.5    Luk, K.D.6
  • 36
    • 67650476919 scopus 로고    scopus 로고
    • Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants
    • Bain S.D., Jerome C., Shen V., Dupin-Roger I., Ammann P. Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants. Osteoporos Int 2009, 20:1417-1428.
    • (2009) Osteoporos Int , vol.20 , pp. 1417-1428
    • Bain, S.D.1    Jerome, C.2    Shen, V.3    Dupin-Roger, I.4    Ammann, P.5
  • 37
    • 79954444751 scopus 로고    scopus 로고
    • Strontium is incorporated into the fracture callus but does not influence the mechanical strength of healing rat fractures
    • Bruel A., Olsen J., Birkedal H., Risager M., Andreassen T.T., Raffalt A.C., et al. Strontium is incorporated into the fracture callus but does not influence the mechanical strength of healing rat fractures. Calcif Tissue Int 2011, 88:142-152.
    • (2011) Calcif Tissue Int , vol.88 , pp. 142-152
    • Bruel, A.1    Olsen, J.2    Birkedal, H.3    Risager, M.4    Andreassen, T.T.5    Raffalt, A.C.6
  • 38
    • 0029812110 scopus 로고    scopus 로고
    • Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (S 12911) administration
    • Boivin G., Deloffre P., Perrat B., Panczer G., Boudeulle M., Mauras Y., et al. Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (S 12911) administration. J Bone Miner Res 1996, 11:1302-1311.
    • (1996) J Bone Miner Res , vol.11 , pp. 1302-1311
    • Boivin, G.1    Deloffre, P.2    Perrat, B.3    Panczer, G.4    Boudeulle, M.5    Mauras, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.