Genetic requirements for Moraxella catarrhalis growth under iron-limiting conditions

Molecular Microbiology

Volumn 87, Issue 1, 2013, Pages 14-29

  de Vries, Stefan P W ^a   Burghout, Peter ^a   Langereis, Jeroen D ^a   Zomer, Aldert ^a   Hermans, Peter W M ^a   Bootsma, Hester J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

IRON; NITRATE REDUCTASE; NITRITE REDUCTASE;

AEROBIC METABOLISM; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL GROWTH; BACTERIUM MUTANT; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; GENETIC COMPLEMENTATION; HIGH THROUGHPUT SCREENING; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IRON DEPLETION; IRON METABOLISM; MORAXELLA CATARRHALIS; NASOPHARYNX; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PHENOTYPE; PRIORITY JOURNAL; TRANSPOSON; YGGW GENE;

GENE DELETION; GENE EXPRESSION PROFILING; HUMANS; IRON; MICROARRAY ANALYSIS; MORAXELLA (BRANHAMELLA) CATARRHALIS; PHENOTYPE; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS); MORAXELLA CATARRHALIS;

EID: 84871461666     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12081     Document Type: Article

References (41)

1. Abicht, H.K., Martinez, J., Layer, G., Jahn, D., and Solioz, M. (2011) Lactococcus lactis HemW (HemN) is a heme-binding protein with a putative role in heme trafficking. Biochem J 442: 335-343.
2. Aebi, C., Stone, B., Beucher, M., Cope, L.D., Maciver, I., Thomas, S.E., etal. (1996) Expression of the CopB outer membrane protein by Moraxella catarrhalis is regulated by iron and affects iron acquisition from transferrin and lactoferrin. Infect Immun 64: 2024-2030.
3. Aebi, C., Lafontaine, E.R., Cope, L.D., Latimer, J.L., Lumbley, S.L., McCracken, G.H., and Hansen, E.J. (1998) Phenotypic effect of isogenic uspA1 and uspA2 mutations on Moraxella catarrhalis 035E. Infect Immun 66: 3113-3119.
4. Akerley, B.J., Rubin, E.J., Camilli, A., Lampe, D.J., Robertson, H.M., and Mekalanos, J.J. (1998) Systematic identification of essential genes by in vitro mariner mutagenesis. Proc Natl Acad Sci USA 95: 8927-8932.
5. Arraiano, C.M., Andrade, J.M., Domingues, S., Guinote, I.B., Malecki, M., Matos, R.G., etal. (2010) The critical role of RNA processing and degradation in the control of gene expression. FEMS Microbiol Rev 34: 883-923.
6. Bijlsma, J.J., Burghout, P., Kloosterman, T.G., Bootsma, H.J., de Jong, A., Hermans, P.W., and Kuipers, O.P. (2007) Development of genomic array footprinting for identification of conditionally essential genes in Streptococcus pneumoniae. Appl Environ Microbiol 73: 1514-1524.
7. Brooks, M.J., Laurence, C.A., Hansen, E.J., and Gray-Owen, S.D. (2007) Characterization of the Moraxella catarrhalis opa-like protein, OlpA, reveals a phylogenetically conserved family of outer membrane proteins. J Bacteriol 189: 76-82.
8. Burghout, P., Bootsma, H.J., Kloosterman, T.G., Bijlsma, J.J., de Jongh, C.E., Kuipers, O.P., and Hermans, P.W. (2007) Search for genes essential for pneumococcal transformation: the RadA DNA repair protein plays a role in genomic recombination of donor DNA. J Bacteriol 189: 6540-6550.
9. Davie, J.J., Earl, J., de Vries, S.P., Ahmed, A., Hu, F.Z., Bootsma, H.J., etal. (2011) Comparative analysis and supragenome modeling of twelve Moraxella catarrhalis clinical isolates. BMC Genomics 12: 70.
10. Delcher, A.L., Harmon, D., Kasif, S., White, O., and Salzberg, S.L. (1999) Improved microbial gene identification with GLIMMER. Nucleic Acids Res 27: 4636-4641.
11. Du, R.P., Wang, Q., Yang, Y.P., Schryvers, A.B., Chong, P., Klein, M.H., and Loosmore, S.M. (1998) Cloning and expression of the Moraxella catarrhalis lactoferrin receptor genes. Infect Immun 66: 3656-3665.
12. Galperin, M.Y., and Koonin, E.V. (2010) From complete genome sequence to 'complete' understanding? Trends Biotechnol 28: 398-406.
13. Guo, F.B., Ou, H.Y., and Zhang, C.T. (2003) ZCURVE: a new system for recognizing protein-coding genes in bacterial and archaeal genomes. Nucleic Acids Res 31: 1780-1789.
14. van Hijum, S.A., de Jong, A., Baerends, R.J., Karsens, H.A., Kramer, N.E., Larsen, R., etal. (2005) A generally applicable validation scheme for the assessment of factors involved in reproducibility and quality of DNA-microarray data. BMC Genomics 6: 77.
15. Hoopman, T.C., Liu, W., Joslin, S.N., Pybus, C., Brautigam, C.A., and Hansen, E.J. (2011) Identification of gene products involved in the oxidative stress response of Moraxella catarrhalis. Infect Immun 79: 745-755.
16. Hoopman, T.C., Liu, W., Joslin, S.N., Pybus, C., Sedillo, J.L., Labandeira-Rey, M., etal. (2012) Use of the chinchilla model for nasopharyngeal colonization to study gene expression by Moraxella catarrhalis. Infect Immun 80: 982-995.
17. Hyatt, D., Chen, G.L., Locascio, P.F., Land, M.L., Larimer, F.W., and Hauser, L.J. (2010) Prodigal: prokaryotic gene recognition and translation initiation site identification. BMC Bioinformatics 11: 119.
18. Kumar, P., Sannigrahi, S., and Tzeng, Y.L. (2012) The Neisseria meningitidis ZnuD zinc receptor contributes to interactions with epithelial cells and supports heme utilization when expressed in Escherichia coli. Infect Immun 80: 657-667.
19. Layer, G., Reichelt, J., Jahn, D., and Heinz, D.W. (2010) Structure and function of enzymes in heme biosynthesis. Protein Sci 19: 1137-1161.
20. Li, Z., Pandit, S., and Deutscher, M.P. (1998) 3′ exoribonucleolytic trimming is a common feature of the maturation of small, stable RNAs in Escherichia coli. Proc Natl Acad Sci USA 95: 2856-2861.
21. Livak, K.J., and Schmittgen, T.D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408.
22. Lukashin, A.V., and Borodovsky, M. (1998) GeneMark.hmm: new solutions for gene finding. Nucleic Acids Res 26: 1107-1115.
23. Molzen, T.E., Burghout, P., Bootsma, H.J., Brandt, C.T., van der Gaast-de Jongh, C.E., Eleveld, M.J., etal. (2011) Genome-wide identification of Streptococcus pneumoniae genes essential for bacterial replication during experimental meningitis. Infect Immun 79: 288-297.
24. Pearson, M.M., and Hansen, E.J. (2007) Identification of gene products involved in biofilm production by Moraxella catarrhalis ETSU-9 in vitro. Infect Immun 75: 4316-4325.
25. Pearson, M.M., Laurence, C.A., Guinn, S.E., and Hansen, E.J. (2006) Biofilm formation by Moraxella catarrhalis in vitro: roles of the UspA1 adhesin and the Hag hemagglutinin. Infect Immun 74: 1588-1596.
26. Perez Vidakovics, M.L., and Riesbeck, K. (2009) Virulence mechanisms of Moraxella in the pathogenesis of infection. Curr Opin Infect Dis 22: 279-285.
27. Perocchi, F., Xu, Z., Clauder-Munster, S., and Steinmetz, L.M. (2007) Antisense artifacts in transcriptome microarray experiments are resolved by actinomycin D. Nucleic Acids Res 35: e128.
28. Pink, M., Verma, N., Rettenmeier, A.W., and Schmitz-Spanke, S. (2010) CBB staining protocol with higher sensitivity and mass spectrometric compatibility. Electrophoresis 31: 593-598.
29. Ratledge, C., and Dover, L.G. (2000) Iron metabolism in pathogenic bacteria. Annu Rev Microbiol 54: 881-941.
30. Riesbeck, K., Tan, T.T., and Forsgren, A. (2006) MID and UspA1/A2 of the human respiratory pathogen Moraxella catarrhalis, and interactions with the human host as basis for vaccine development. Acta Biochim Pol 53: 445-456.
31. Sethi, S., and Murphy, T.F. (2008) Infection in the pathogenesis and course of chronic obstructive pulmonary disease. N Engl J Med 359: 2355-2365.
32. Simon, A., and Biot, E. (2010) ANAIS: analysis of NimbleGen arrays interface. Bioinformatics 26: 2468-2469.
33. Skaar, E.P. (2010) The battle for iron between bacterial pathogens and their vertebrate hosts. PLoS Pathog 6: e1000949.
34. Storey, J.D., and Tibshirani, R. (2003) Statistical significance for genomewide studies. Proc Natl Acad Sci USA 100: 9440-9445.
35. Szklarczyk, D., Franceschini, A., Kuhn, M., Simonovic, M., Roth, A., Minguez, P., etal. (2011) The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic Acids Res 39: D561-D568.
36. Vidakovics, M.L., Lamberti, Y., Serra, D., Berbers, G.A., van der Pol, W.L., and Rodriguez, M.E. (2007) Iron stress increases Bordetella pertussis mucin-binding capacity and attachment to respiratory epithelial cells. FEMS Immunol Med Microbiol 51: 414-421.
37. de Vries, S., Bootsma, H.J., Hays, J., and Hermans, P.W. (2009) Molecular aspects of Moraxella catarrhalis pathogenesis. Microbiol Mol Biol Rev 73: 389-406.
38. de Vries, S., van Hijum, S.A., Schueler, W., Riesbeck, K., Hays, J., Hermans, P.W., and Bootsma, H.J. (2010) Genome analysis of Moraxella catarrhalis strain RH4, a human respiratory tract pathogen. J Bacteriol 192: 3574-3583.
39. Wang, W., and Hansen, E.J. (2006) Plasmid pWW115, a cloning vector for use with Moraxella catarrhalis. Plasmid 56: 133-137.
40. Wang, W., Reitzer, L., Rasko, D.A., Pearson, M.M., Blick, R.J., Laurence, C., and Hansen, E.J. (2007) Metabolic analysis of Moraxella catarrhalis and the effect of selected in vitro growth conditions on global gene expression. Infect Immun 75: 4959-4971.
41. Whitby, P.W., Seale, T.W., Morton, D.J., VanWagoner, T.M., and Stull, T.L. (2010) Characterization of the Haemophilus influenzae tehB gene and its role in virulence. Microbiology 156: 1188-1200.