Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: Comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)

Biochemical Journal

Volumn 449, Issue 2, 2013, Pages 531-542

  Hadfield, Katrina A ^a   Pattison, David I ^a,b   Brown, Bronwyn E ^a,b   Hou, Liming ^a   Rye, Kerry Anne ^a,b   Davies, Michael J ^a,b   Hawkins, Clare L ^a,b  

^a HEART RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Atherosclerosis; Cholesterol efflux; High density lipoprotein; Hypothiocyanous acid; Myeloperoxidase; Protein oxidation

Indexed keywords

AMINO ACID; APOLIPOPROTEIN A1; CELL ADHESION MOLECULE; CHOLESTEROL; CHOLESTEROL ESTER; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HIGH DENSITY LIPOPROTEIN; HOMOCITRULLINE; HYPOCHLOROUS ACID; INTERCELLULAR ADHESION MOLECULE 1; LOW DENSITY LIPOPROTEIN; LYSINE; MYELOPEROXIDASE; TRYPTOPHAN; VASCULAR CELL ADHESION MOLECULE 1;

AMINO ACID ANALYSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CARBAMOYLATION; CELL VIABILITY; CHOLESTEROL TRANSPORT; DECOMPOSITION; HUMAN; HUMAN CELL; MACROPHAGE; OXIDATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN HYDROLYSIS; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; APOLIPOPROTEIN A-I; BIOLOGICAL TRANSPORT; CELL LINE; CELLS, CULTURED; CHOLESTEROL; E-SELECTIN; ENDOTHELIUM, VASCULAR; FEMALE; FLOW CYTOMETRY; HUMANS; HYPOCHLOROUS ACID; INTERCELLULAR ADHESION MOLECULE-1; LIPOPROTEINS, HDL; MACROPHAGES; MALE; MOLECULAR SEQUENCE DATA; OXIDANTS; OXIDATION-REDUCTION; PEPTIDES; PEROXIDASE; THIOCYANATES; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84871440206     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121210     Document Type: Article

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