Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions

Journal of Biological Chemistry

Volumn 287, Issue 9, 2012, Pages 6375-6386

  Shao, Baohai ^a   Pennathur, Subramaniam ^b   Heinecke, Jay W ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3-NITROTYROSINE; APOLIPOPROTEIN A-I; ATHEROSCLEROTIC LESIONS; CARDIO-VASCULAR DISEASE; CARDIOPROTECTIVE EFFECT; CHOLESTEROL EFFLUX; HIGH DENSITY LIPOPROTEIN; IN-VITRO; IN-VIVO; MYELOPEROXIDASE; NATIVE FORMS; OXIDATIVE DAMAGE; REGIOSPECIFIC OXIDATION; SELECTED REACTION MONITORING; SITE-SPECIFIC; TANDEM MASS SPECTROMETRY; THERAPEUTIC AGENTS; TYROSINE RESIDUES;

AMINO ACIDS; CHLORINATION; MASS SPECTROMETRY; NITRATION; TISSUE;

OXIDATION;

3 CHLOROTYROSINE; 3 NITROTYROSINE; ABC TRANSPORTER A1; APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN; MYELOPEROXIDASE; TYROSINE;

ADULT; ARTICLE; ATHEROSCLEROSIS; CHEMICAL REACTION; CHLORINATION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HEART PROTECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ION EXCHANGE CHROMATOGRAPHY; LIPID OXIDATION; LIQUID CHROMATOGRAPHY; MALE; NEUTROPHIL; NITRATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY;

APOLIPOPROTEIN A-I; ATHEROSCLEROSIS; HALOGENATION; HUMANS; HYPOCHLOROUS ACID; LIPOPROTEINS, HDL; NITROGEN; OXIDATION-REDUCTION; OXIDATIVE STRESS; PEROXIDASE; PROTEIN PROCESSING, POST-TRANSLATIONAL; TYROSINE;

EID: 84857491459     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.337345     Document Type: Article

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