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Volumn 19, Issue 1, 2013, Pages 116-127

Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo

Author keywords

DsRed; Enhanced green fluorescent protein; Epithelial mesenchymal transition; In vivo imaging; pre mRNA splicing; Wound healing

Indexed keywords

FIBROBLAST GROWTH FACTOR 2;

EID: 84871420608     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.035097.112     Document Type: Article
Times cited : (23)

References (35)
  • 1
    • 0344629426 scopus 로고    scopus 로고
    • A stem structure in fibroblast growth factor receptor 2 transcripts mediates cell-type-specific splicing by approximating intronic control elements
    • Baraniak AP, Lasda EL, Wagner EJ, Garcia-Blanco MA. 2003. A stem structure in fibroblast growth factor receptor 2 transcripts mediates cell-type-specific splicing by approximating intronic control elements. Mol Cell Biol 23: 9327-9337.
    • (2003) Mol Cell Biol , vol.23 , pp. 9327-9337
    • Baraniak, A.P.1    Lasda, E.L.2    Wagner, E.J.3    Garcia-Blanco, M.A.4
  • 2
    • 32044467372 scopus 로고    scopus 로고
    • Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice
    • Baraniak AP, Chen JR, Garcia-Blanco MA. 2006. Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice. Mol Cell Biol 26: 1209-1222.
    • (2006) Mol Cell Biol , vol.26 , pp. 1209-1222
    • Baraniak, A.P.1    Chen, J.R.2    Garcia-Blanco, M.A.3
  • 3
    • 33845270164 scopus 로고    scopus 로고
    • Imaging the alternative silencing of FGFR2 exon IIIb in vivo
    • Bonano VI, Oltean S, Brazas RM, Garcia-Blanco MA. 2006. Imaging the alternative silencing of FGFR2 exon IIIb in vivo. RNA 12: 2073-2079.
    • (2006) RNA , vol.12 , pp. 2073-2079
    • Bonano, V.I.1    Oltean, S.2    Brazas, R.M.3    Garcia-Blanco, M.A.4
  • 4
    • 38449111801 scopus 로고    scopus 로고
    • A protocol for imaging alternative splicing regulation in vivo using fluorescence reporters in transgenic mice
    • Bonano VI, Oltean S, Garcia-Blanco MA. 2007. A protocol for imaging alternative splicing regulation in vivo using fluorescence reporters in transgenic mice. Nat Protoc 2: 2166-2181.
    • (2007) Nat Protoc , vol.2 , pp. 2166-2181
    • Bonano, V.I.1    Oltean, S.2    Garcia-Blanco, M.A.3
  • 5
    • 13644267108 scopus 로고    scopus 로고
    • Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle
    • Brooks AR, Harkins RN, Wang P, Qian HS, Liu P, Rubanyi GM. 2004. Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle. J Gene Med 6: 395-404.
    • (2004) J Gene Med , vol.6 , pp. 395-404
    • Brooks, A.R.1    Harkins, R.N.2    Wang, P.3    Qian, H.S.4    Liu, P.5    Rubanyi, G.M.6
  • 6
    • 80051613693 scopus 로고    scopus 로고
    • A comparison of exogenous promoter activity at the ROSA26 locus using a PhiC31 integrase mediated cassette exchange approach in mouse ES cells
    • doi: 10.1371/journal.pone.0023376
    • Chen CM, Krohn J, Bhattacharya S, Davies B. 2011. A comparison of exogenous promoter activity at the ROSA26 locus using a PhiC31 integrase mediated cassette exchange approach in mouse ES cells. PLoS ONE 6: e23376. doi: 10.1371/journal.pone.0023376.
    • (2011) PLoS ONE , vol.6
    • Chen, C.M.1    Krohn, J.2    Bhattacharya, S.3    Davies, B.4
  • 7
    • 78049416081 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing regulation in cancer: Pathways and programs unhinged
    • David CJ, Manley JL. 2010. Alternative pre-mRNA splicing regulation in cancer: Pathways and programs unhinged. Genes Dev 24: 2343-2364.
    • (2010) Genes Dev , vol.24 , pp. 2343-2364
    • David, C.J.1    Manley, J.L.2
  • 8
    • 0026739404 scopus 로고
    • A novel form of fibroblast growth factor receptor 2. Alternative splicing of the third immunoglobulin-like domain confers ligand binding specificity
    • Dell KR, Williams LT. 1992. A novel form of fibroblast growth factor receptor 2. Alternative splicing of the third immunoglobulin-like domain confers ligand binding specificity. J Biol Chem 267: 21225-21229.
    • (1992) J Biol Chem , vol.267 , pp. 21225-21229
    • Dell, K.R.1    Williams, L.T.2
  • 9
    • 0030665570 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells
    • Feng S, Wang F, Matsubara A, Kan M, McKeehan WL. 1997. Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells. Cancer Res 57: 5369-5378.
    • (1997) Cancer Res , vol.57 , pp. 5369-5378
    • Feng, S.1    Wang, F.2    Matsubara, A.3    Kan, M.4    McKeehan, W.L.5
  • 10
    • 39749157093 scopus 로고    scopus 로고
    • Sustained TGF β exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis
    • Gal A, Sjoblom T, Fedorova L, Imreh S, Beug H, Moustakas A. 2008. Sustained TGF β exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis. Oncogene 27: 1218-1230.
    • (2008) Oncogene , vol.27 , pp. 1218-1230
    • Gal, A.1    Sjoblom, T.2    Fedorova, L.3    Imreh, S.4    Beug, H.5    Moustakas, A.6
  • 12
    • 27944458349 scopus 로고    scopus 로고
    • Visualization of alternative splicing in vivo
    • Kemp PR, Ellis PD, Smith CW. 2005. Visualization of alternative splicing in vivo. Methods 37: 360-367.
    • (2005) Methods , vol.37 , pp. 360-367
    • Kemp, P.R.1    Ellis, P.D.2    Smith, C.W.3
  • 13
    • 77955873421 scopus 로고    scopus 로고
    • Visualization and genetic analysis of alternative splicing regulation in vivo using fluorescence reporters in transgenic Caenorhabditis elegans
    • Kuroyanagi H, Ohno G, Sakane H, Maruoka H, Hagiwara M. 2010. Visualization and genetic analysis of alternative splicing regulation in vivo using fluorescence reporters in transgenic Caenorhabditis elegans. Nat Protoc 5: 1495-1517.
    • (2010) Nat Protoc , vol.5 , pp. 1495-1517
    • Kuroyanagi, H.1    Ohno, G.2    Sakane, H.3    Maruoka, H.4    Hagiwara, M.5
  • 15
    • 50249176008 scopus 로고    scopus 로고
    • hnRNP H and hnRNP F Complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc
    • Mauger DM, Lin C, Garcia-Blanco MA. 2008. hnRNP H and hnRNP F Complex with Fox2 to silence fibroblast growth factor receptor 2 exon IIIc. Mol Cell Biol 28: 5403-5419.
    • (2008) Mol Cell Biol , vol.28 , pp. 5403-5419
    • Mauger, D.M.1    Lin, C.2    Garcia-Blanco, M.A.3
  • 16
    • 0036096533 scopus 로고    scopus 로고
    • An ex vivo assay to assess the potential of skin keratinocytes for wound epithelialization
    • Mazzalupo S, Wawersik MJ, Coulombe PA. 2002. An ex vivo assay to assess the potential of skin keratinocytes for wound epithelialization. J Invest Dermatol 118: 866-870.
    • (2002) J Invest Dermatol , vol.118 , pp. 866-870
    • Mazzalupo, S.1    Wawersik, M.J.2    Coulombe, P.A.3
  • 17
    • 56949090665 scopus 로고    scopus 로고
    • Epigenetic regulation of cytomegalovirus major immediate-early promoter activity in transgenic mice
    • Mehta AK, Majumdar SS, Alam P, Gulati N, Brahmachari V. 2009. Epigenetic regulation of cytomegalovirus major immediate-early promoter activity in transgenic mice. Gene 428: 20-24.
    • (2009) Gene , vol.428 , pp. 20-24
    • Mehta, A.K.1    Majumdar, S.S.2    Alam, P.3    Gulati, N.4    Brahmachari, V.5
  • 18
    • 0037147250 scopus 로고    scopus 로고
    • A non-sequence-specific double-stranded RNA structural element regulates splicing of two mutually exclusive exons of fibroblast growth factor receptor 2 (FGFR2)
    • Muh SJ. 2002. A non-sequence-specific double-stranded RNA structural element regulates splicing of two mutually exclusive exons of fibroblast growth factor receptor 2 (FGFR2). J Biol Chem 277: 50143-50154.
    • (2002) J Biol Chem , vol.277 , pp. 50143-50154
    • Muh, S.J.1
  • 19
    • 78650678823 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in the skin
    • Nakamura M, Tokura Y. 2011. Epithelial-mesenchymal transition in the skin. J Dermatol Sci 61: 7-13.
    • (2011) J Dermatol Sci , vol.61 , pp. 7-13
    • Nakamura, M.1    Tokura, Y.2
  • 20
    • 33749025816 scopus 로고    scopus 로고
    • Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity
    • Oltean S. 2006. Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity. Proc Natl Acad Sci 103: 14116-14121.
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 14116-14121
    • Oltean, S.1
  • 21
    • 47549109962 scopus 로고    scopus 로고
    • Dunning rat prostate adenocarcinomas and alternative splicing reporters: Powerful tools to study epithelial plasticity in prostate tumors in vivo
    • Oltean S, Febbo PG, Garcia-Blanco MA. 2008. Dunning rat prostate adenocarcinomas and alternative splicing reporters: Powerful tools to study epithelial plasticity in prostate tumors in vivo. Clin Exp Metastasis 25: 611-619.
    • (2008) Clin Exp Metastasis , vol.25 , pp. 611-619
    • Oltean, S.1    Febbo, P.G.2    Garcia-Blanco, M.A.3
  • 22
    • 0030794460 scopus 로고    scopus 로고
    • Cell type-specific inhibition of keratinocyte collagenase-1 expression by basic fibroblast growth factor and keratinocyte growth factor. A common receptor pathway
    • Pilcher BK, Gaither-Ganim J, Parks WC, Welgus HG. 1997. Cell type-specific inhibition of keratinocyte collagenase-1 expression by basic fibroblast growth factor and keratinocyte growth factor. A common receptor pathway. J Biol Chem 272: 18147-18154.
    • (1997) J Biol Chem , vol.272 , pp. 18147-18154
    • Pilcher, B.K.1    Gaither-Ganim, J.2    Parks, W.C.3    Welgus, H.G.4
  • 23
    • 0027992204 scopus 로고
    • Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial-mesenchymal transition in rat bladder carcinoma cells
    • Savagner P, Valles AM, Jouanneau J, Yamada KM, Thiery JP. 1994. Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial-mesenchymal transition in rat bladder carcinoma cells. Mol Biol Cell 5: 851-862.
    • (1994) Mol Biol Cell , vol.5 , pp. 851-862
    • Savagner, P.1    Valles, A.M.2    Jouanneau, J.3    Yamada, K.M.4    Thiery, J.P.5
  • 24
    • 80052322960 scopus 로고    scopus 로고
    • An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype
    • doi: 10.1371/journal.pgen.1002218
    • Shapiro IM, Cheng AW, Flytzanis NC, Balsamo M, Condeelis JS, Oktay MH, Burge CB, Gertler FB. 2011. An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype. PLoS Genet 7: e1002218. doi: 10.1371/journal.pgen.1002218.
    • (2011) PLoS Genet , vol.7
    • Shapiro, I.M.1    Cheng, A.W.2    Flytzanis, N.C.3    Balsamo, M.4    Condeelis, J.S.5    Oktay, M.H.6    Burge, C.B.7    Gertler, F.B.8
  • 26
    • 35548970476 scopus 로고    scopus 로고
    • Expression of transgenes targeted to the Gt(ROSA)26Sor locus is orientation dependent
    • doi: 10.1371/journal.pone.0000004
    • Strathdee D, Ibbotson H, Grant SG. 2006. Expression of transgenes targeted to the Gt(ROSA)26Sor locus is orientation dependent. PLoS ONE 1: e4. doi: 10.1371/journal.pone.0000004.
    • (2006) PLoS ONE , vol.1
    • Strathdee, D.1    Ibbotson, H.2    Grant, S.G.3
  • 27
    • 77956205314 scopus 로고    scopus 로고
    • Splicing reporter mice revealed the evolutionally conserved switching mechanism of tissue-specific alternative exon selection
    • doi: 10.1371/journal.pone.0010946
    • Takeuchi A, Hosokawa M, Nojima T, Hagiwara M. 2010. Splicing reporter mice revealed the evolutionally conserved switching mechanism of tissue-specific alternative exon selection. PLoS ONE 5: e10946. doi: 10.1371/journal.pone. 0010946.
    • (2010) PLoS ONE , vol.5
    • Takeuchi, A.1    Hosokawa, M.2    Nojima, T.3    Hagiwara, M.4
  • 28
    • 75149170979 scopus 로고    scopus 로고
    • Fibroblast growth factor signalling: From development to cancer
    • Turner N, Grose R. 2010. Fibroblast growth factor signalling: From development to cancer. Nat Rev Cancer 10: 116-129.
    • (2010) Nat Rev Cancer , vol.10 , pp. 116-129
    • Turner, N.1    Grose, R.2
  • 29
    • 77957726684 scopus 로고    scopus 로고
    • Sam68 regulates EMT through alternative splicing-activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene
    • Valacca C, Bonomi S, Buratti E, Pedrotti S, Baralle FE, Sette C, Ghigna C, Biamonti G. 2010. Sam68 regulates EMT through alternative splicing-activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene. J Cell Biol 191: 87-99.
    • (2010) J Cell Biol , vol.191 , pp. 87-99
    • Valacca, C.1    Bonomi, S.2    Buratti, E.3    Pedrotti, S.4    Baralle, F.E.5    Sette, C.6    Ghigna, C.7    Biamonti, G.8
  • 32
    • 61649087689 scopus 로고    scopus 로고
    • ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
    • Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP. 2009. ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell 33: 591-601.
    • (2009) Mol Cell , vol.33 , pp. 591-601
    • Warzecha, C.C.1    Sato, T.K.2    Nabet, B.3    Hogenesch, J.B.4    Carstens, R.P.5
  • 33
    • 0035196621 scopus 로고    scopus 로고
    • Increased levels of keratin 16 alter epithelialization potential of mouse skin keratinocytes in vivo and ex vivo
    • Wawersik MJ, Mazzalupo S, Nguyen D, Coulombe PA. 2001. Increased levels of keratin 16 alter epithelialization potential of mouse skin keratinocytes in vivo and ex vivo. Mol Biol Cell 12: 3439-3450.
    • (2001) Mol Biol Cell , vol.12 , pp. 3439-3450
    • Wawersik, M.J.1    Mazzalupo, S.2    Nguyen, D.3    Coulombe, P.A.4
  • 35
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
    • Yang J, Weinberg RA. 2008. Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis. Dev Cell 14: 818-829.
    • (2008) Dev Cell , vol.14 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.