High Serum Carotenoids Associated with Lower Risk for Bone Loss and Osteoporosis in Post-Menopausal Japanese Female Subjects: Prospective Cohort Study

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Sugiura, Minoru ^a   Nakamura, Mieko ^b   Ogawa, Kazunori ^a   Ikoma, Yoshinori ^a   Yano, Masamichi ^a  

^a NATIONAL INSTITUTE OF FRUIT TREE SCIENCE   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CAROTENE; BETA CAROTENE; BETA CRYPTOXANTHIN; CAROTENOID; LYCOPENE; XANTHOPHYLL; ZEAXANTHIN;

ADULT; AGED; ARTICLE; BONE DENSITY; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; JAPANESE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OSTEOPENIA; POSTMENOPAUSE OSTEOPOROSIS; PREMENOPAUSE; PROSPECTIVE STUDY; RADIUS; RETROSPECTIVE STUDY; VITAMIN BLOOD LEVEL;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BONE DENSITY; CAROTENOIDS; FEMALE; FOLLOW-UP STUDIES; HUMANS; JAPAN; MALE; MIDDLE AGED; OSTEOPOROSIS; PERIMENOPAUSE; PROSPECTIVE STUDIES; RISK;

EID: 84871412360     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052643     Document Type: Article

References (41)

1. Ministry of Health, Labor and Welfare. Comprehensive survey of living conditions of the people on Health and Welfare. Section3 2004. Internet: http://www.mhlw.go.jp/toukei/saikin/hw/k-tyosa/k-tyosa04/4-2.html (accessed 11 July 2012).
2. Christodoulou C, Cooper C, (2003) What is osteoporosis? Postgrad Med J 79: 133-138.
3. Gennari C, (2001) Calcium and vitamin D nutrition and bone disease of the elderly. Public Health Nutr 4: 547-559.
4. Prentice A, (2004) Diet, nutrition and the prevention of osteoporosis. Public Health Nutr 7: 227-243.
5. Macdonald HM, New SA, Golden MH, Campbell MK, Reid DM, (2004) Nutritional associations with bone loss during the menopausal transition: evidence of a beneficial effect of calcium, alcohol, and fruit and vegetable nutrients and of a detrimental effect of fatty acids. Am J Clin Nutr 79: 155-165.
6. New SA, Bolton-Smith C, Grubb DA, Reid DM, (1997) Nutritional influences on bone mineral density: a cross-sectional study in premenopausal women. Am J Clin Nutr 65: 1831-1839.
7. Prynne CJ, Mishra GD, O'Connell MA, Muniz G, Laskey MA, et al. (2006) Fruit and vegetable intakes and bone mineral status: a cross sectional study in 5 age and sex cohorts. Am J Clin Nutr 83: 1420-1428.
8. Okubo H, Sasaki S, Horiguchi H, Oguma E, Miyamoto K, et al. (2006) Dietary patterns associated with bone mineral density in premenopausal Japanese farmwomen. Am J Clin Nutr 83: 1185-1192.
9. McGartland CP, Robson PJ, Murray LJ, Cran GW, Savage MJ, et al. (2004) Fruit and vegetable consumption and bone mineral density: the Northern Ireland Young Hearts Project. Am J Clin Nutr 80: 1019-1023.
10. Tucker KL, Chen H, Hanna MT, Couples LA, Wilson PW, et al. (2002) Bone mineral density and dietary patterns in older adults: the Framingham Osteoporosis Study. Am J Clin Nutr 76: 245-252.
11. Gutteridge JM, (1994) Biological origin of free radicals, and mechanisms of antioxidant protection. Chem Biol Interact 91: 133-140.
12. Rock CL, Jacob RA, Bowen PE, (1996) Update on the biological characteristics of the antioxidant micronutrients: vitamin C, vitamin E, and the carotenoids. J Am Diet Assoc 96: 693-702.
13. Almeida M, Han L, Martin-Millan M, O'Brien CA, Manolagas SC, (2007) Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription. J Biol Chem 282: 27298-27305.
14. Jilka RL, Weinstein RS, Parfitt AM, Manolagas SC, (2007) Quantifying osteoblast and osteocyte apoptosis: challenges and rewards. J Bone Miner Res 22: 1492-1501.
15. Garrett IR, Boyce BF, Oreffo RO, Bonewald L, Poser J, et al. (1990) Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. J Clin Invest 85: 632-639.
16. Basu S, Michaelsson K, Olofsson H, Johansson S, Melhus H, (2001) Association between oxidative stress and bone mineral density. Biochem Biophys Res Commun 288: 275-279.
17. Yalin S, Bagis S, Polat G, (2005) Is there a role of free oxygen radicals in primary male osteoporosis? Clin Exp Rheumatol. 23: 689-692.
18. Law MR, Hackshaw AK, (1997) A meta-analysis of cigarette smoking, bone mineral density and risk of hip fracture: recognition of a major effect. BMJ 315: 841-846.
19. Melhus H, Michaelsson K, Holmberg L, Wolk A, Ljunghall S, (1999) Smoking, antioxidant vitamins, and the risk of hip fracture. J Bone Miner Res 14: 129-135.
20. Maggio D, Barabani M, Pierandrei M, (2003) Marked decrease in plasma antioxidants in aged osteoporotic women: results of a cross-sectional study. J Clin Endocrinol Metab 88: 1523-1527.
21. Wattanapenpaiboon N, Lukito W, Wahlqvist ML, Strauss BJ, (2003) Dietary carotenoid intake as a predictor of bone mineral density. Asia Pac J Clin Nutr 12: 467-473.
22. Maggio D, Polidori MC, Barabani M, Tufi A, Ruggiero C, et al. (2006) Low levels of carotenoids and retinol in involutional osteoporosis. Bone 38: 244-248.
23. Yang Z, Zhang Z, Penniston KL, Binkley N, Tanumihardjo SA, (2008) Serum carotenoid concentrations in postmenopausal women from the United States with and without osteoporosis. Int J Vitam Nutr Res 78: 105-111.
24. Sahni S, Hannan MT, Blumberg J, Cupples LA, Kiel DP, et al. (2009) Inverse association of carotenoid intakes with 4-y change in bone mineral density in elderly men and women: the Framingham Osteoporosis Study. Am J Clin Nutr 89: 416-424.
25. Sahni S, Hannan MT, Gagnon D, Blumberg J, Cupples LA, et al. (2009) Protective effect of total and supplemental vitamin C intake on the risk of hip fracture-a 17-year follow-up from the Framingham Osteoporosis Study. Osteoporos Int 20: 1853-1861.
26. Sugiura M, Nakamura M, Ogawa K, Ikoma Y, Ando F, et al. (2008) Bone mineral density in post-menopausal female subjects is associated with serum antioxidant carotenoids. Osteoporos Int 19: 211-219.
27. Sugiura M, Nakamura M, Ogawa K, Ikoma Y, Ando F, et al. (2011) Dietary patterns of antioxidant vitamin and carotenoid intake associated with bone mineral density: Findings from post-menopausal Japanese female subjects. Osteoporos Int 22: 143-152.
28. Wakai K, Egami I, Kato K, Lin Y, Kawamura T, et al. (1999) A simple food frequency questionnaire for Japanese diet-Part I. Development of the questionnaire, and reproducibility and validity for food groups. J Epidemiol 9: 216-226.
29. Egami I, Wakai K, Kato K, Lin Y, Kawamura T, et al. (1999) A simple food frequency questionnaire for Japanese diet-Part II. Reproducibility and validity for nutrient intakes. J Epidemiol 9: 227-234.
30. Science and Technology Agency (1983) Standard tables of food composition in Japan. 4th ed. Tokyo, Japan: Printing Bureau, Ministry of Finance. (in Japanese).
31. Science and Technology Agency (1997) Standard tables of food composition in Japan. 5th ed. (for new foods) Tokyo, Japan: Printing Bureau, Ministry of Finance. (in Japanese).
32. Sugiura M, Nakamura M, Ikoma Y, Yano M, Ogawa K, et al. (2005) High serum carotenoids are inversely associated with serum gamma-glutamyltransferase in alcohol drinkers within normal liver function. J Epidemiol 15: 180-186.
33. Orimo H, Hayashi Y, Fukunaga M, Sone T, Fujiwara S, et al. (2001) Diagnostic criteria for primary osteoporosis: year 2000 revision. J Bone Miner Metab 19: 331-337.
34. Iotsova V, Caamaño J, Loy J, Yang Y, Lewin A, et al. (1997) Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2. Nat Med 3: 1285-1289.
35. Baeuerle PA, Rupec RA, Pahl HL, (1996) Reactive oxygen intermediates as second messengers of a general pathogen response. Pathol Biol (Paris) 44: 29-35.
36. Garrett IR, Boyce BF, Oreffo RO, Bonewald L, Poser J, et al. (1990) Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. J Clin Invest 85: 632-639.
37. Bax BE, Alam AS, Banerji B, Bax CM, Bevis PJ, et al. (1992) Stimulation of osteoclastic bone resorption by hydrogen peroxide. Biochem Biophys Res Commun 183: 1153-1158.
38. Yamaguchi M, Uchiyama S, (2003) Effect of carotenoid on calcium content and alkaline phosphatase activity in rat femoral tissues in vitro: the unique anabolic effect of beta-cryptoxanthin. Biol Pharm Bull 26: 1188-1191.
39. Yamaguchi M, Uchiyama S, (2004) beta-Cryptoxanthin stimulates bone formation and inhibits bone resorption in tissue culture in vitro. Mol Cell Biochem 258: 137-144.
40. Uchiyama S, Yamaguchi M, (2004) Oral administration of beta-cryptoxanthin induces anabolic effects on bone components in the femoral tissues of rats in vivo. Biol Pharm Bull 27: 232-235.
41. Sugiura M, Nakamura M, Ogawa K, Ikoma Y, Matsumoto H, et al. (2009) Synergistic interaction of cigarette smoking and alcohol drinking with serum carotenoid concentrations: findings from the middle-Japanese population. Br J Nutr 102: 1211-1219.