메뉴 건너뛰기




Volumn 30, Issue 1, 2013, Pages 10-20

Brain targeting of Atorvastatin loaded amphiphilic PLGA-b-PEG nanoparticles

Author keywords

Atorvastatin; Brain targeting; Nanoparticles; PLGA b PEG; Polysorbate 80

Indexed keywords

ATORVASTATIN; MACROGOL; NANOPARTICLE; POLYGLACTIN; POLYSORBATE 80;

EID: 84871403165     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.3109/02652048.2012.692400     Document Type: Article
Times cited : (52)

References (41)
  • 1
    • 79957490620 scopus 로고    scopus 로고
    • Development and characterization of Cyclosporine A loaded nanoparti-cles for ocular drug delivery: Cellular toxicity, uptake, and kinetic studies
    • Aksungur P, Demirbilek M, Denkbas EB, Vandervoort J, Ludwig A, Unlu N. Development and characterization of Cyclosporine A loaded nanoparti-cles for ocular drug delivery: Cellular toxicity, uptake, and kinetic studies. J Control Release, 2011;151:286-94.
    • (2011) J Control Release , vol.151 , pp. 286-294
    • Aksungur, P.1    Demirbilek, M.2    Denkbas, E.B.3    Vandervoort, J.4    Ludwig, A.5    Unlu, N.6
  • 2
    • 30844462755 scopus 로고    scopus 로고
    • Body distribution of polysorbate-80 and doxorubicin-loaded [14C]poly(butyl cyanoacrylate) nanoparticles after i.v. administration in rats
    • Ambruosi A, Yamamoto H, Kreuter J. Body distribution of polysorbate-80 and doxorubicin-loaded [14C]poly(butyl cyanoacrylate) nanoparticles after i.v. administration in rats. J Drug Target, 2005;13:535-42.
    • (2005) J Drug Target , vol.13 , pp. 535-542
    • Ambruosi, A.1    Yamamoto, H.2    Kreuter, J.3
  • 4
    • 33646397592 scopus 로고    scopus 로고
    • Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells
    • Chithrani BD, Ghazani AA, Chan WC. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett, 2006;6:662-8.
    • (2006) Nano Lett , vol.6 , pp. 662-668
    • Chithrani, B.D.1    Ghazani, A.A.2    Chan, W.C.3
  • 5
    • 78649636202 scopus 로고    scopus 로고
    • Inorganic nanoparticle-based contrast agents for molecular imaging
    • Cho EC, Glaus C, Chen J, Welch MJ, Xia Y. Inorganic nanoparticle-based contrast agents for molecular imaging. Trends Mol Med, 2010;16:561-73.
    • (2010) Trends Mol Med , vol.16 , pp. 561-573
    • Cho, E.C.1    Glaus, C.2    Chen, J.3    Welch, M.J.4    Xia, Y.5
  • 6
    • 79960942844 scopus 로고    scopus 로고
    • Polymer therapeutics as nanomedicines: New perspectives
    • Duncan R. Polymer therapeutics as nanomedicines: New perspectives. Curr Opin Biotechnol, 2011;22:492-501.
    • (2011) Curr Opin Biotechnol , vol.22 , pp. 492-501
    • Duncan, R.1
  • 7
    • 77956312910 scopus 로고    scopus 로고
    • A quadruped study on chitosan microspheres containing atorvastatin calcium: Preparation, characterization, quantification and in-vivo application
    • Eroglu H, Nemutlu E, Turkoglu OF, Nacar O, Bodur E, Sargon MF, Beskonakli E, Oner L. A quadruped study on chitosan microspheres containing atorvastatin calcium: Preparation, characterization, quantification and in-vivo application. Chem Pharm Bull (Tokyo), 2010;58:1161-7.
    • (2010) Chem Pharm Bull (Tokyo) , vol.58 , pp. 1161-1167
    • Eroglu, H.1    Nemutlu, E.2    Turkoglu, O.F.3    Nacar, O.4    Bodur, E.5    Sargon, M.F.6    Beskonakli, E.7    Oner, L.8
  • 9
    • 79251591020 scopus 로고    scopus 로고
    • Formulation of chitosan-TPP-pDNA nanocapsules for gene therapy applications
    • Gaspar VM, Sousa F, Queiroz JA, Correia IJ. Formulation of chitosan-TPP-pDNA nanocapsules for gene therapy applications. Nanotechnology, 2011;22(1):1-12.
    • (2011) Nanotechnology , vol.22 , Issue.1 , pp. 1-12
    • Gaspar, V.M.1    Sousa, F.2    Queiroz, J.A.3    Correia, I.J.4
  • 11
    • 0021923858 scopus 로고
    • Nile red: A selective fluorescent stain for intracellular lipid droplets
    • Greenspan P, Mayer EP, Fowler SD. Nile red: A selective fluorescent stain for intracellular lipid droplets. J Cell Biol, 1985;100:965-73.
    • (1985) J Cell Biol , vol.100 , pp. 965-973
    • Greenspan, P.1    Mayer, E.P.2    Fowler, S.D.3
  • 12
    • 77950953230 scopus 로고    scopus 로고
    • Multifunctional nanocarriers for cell imaging, drug delivery, and near-IR photothermal therapy
    • Guo R, Zhang L, Qian H, Li R, Jiang X, Liu B. Multifunctional nanocarriers for cell imaging, drug delivery, and near-IR photothermal therapy. Langmuir, 2010;26:5428-34.
    • (2010) Langmuir , vol.26 , pp. 5428-5434
    • Guo, R.1    Zhang, L.2    Qian, H.3    Li, R.4    Jiang, X.5    Liu, B.6
  • 13
    • 78650402481 scopus 로고    scopus 로고
    • Nanoparticle-mediated interleukin-12 cancer gene therapy
    • Hallaj-Nezhadi S, Lotfipour F, Dass C. Nanoparticle-mediated interleukin-12 cancer gene therapy. J Pharm Pharm Sci, 2010;13:472-85.
    • (2010) J Pharm Pharm Sci , vol.13 , pp. 472-485
    • Hallaj-Nezhadi, S.1    Lotfipour, F.2    Dass, C.3
  • 14
    • 77249104877 scopus 로고    scopus 로고
    • Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles
    • He C, Hu Y, Yin L, Tang C, Yin C. Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials, 2010;31:3657-66.
    • (2010) Biomaterials , vol.31 , pp. 3657-3666
    • He, C.1    Hu, Y.2    Yin, L.3    Tang, C.4    Yin, C.5
  • 15
    • 78650053505 scopus 로고    scopus 로고
    • The rise and rise of stealth nanocarriers for cancer therapy: Passive versus active targeting
    • Huynh NT, Roger E, Lautram N, Benoit JP, Passirani C. The rise and rise of stealth nanocarriers for cancer therapy: Passive versus active targeting. Nanomedicine (Lond), 2010;5:1415-33.
    • (2010) Nanomedicine (Lond) , vol.5 , pp. 1415-1433
    • Huynh, N.T.1    Roger, E.2    Lautram, N.3    Benoit, J.P.4    Passirani, C.5
  • 16
    • 79952114016 scopus 로고    scopus 로고
    • Anti-cancer drug loaded iron-gold core-shell nanoparticles (Fe@Au) for magnetic drug targeting
    • Kayal S, Ramanujan RV. Anti-cancer drug loaded iron-gold core-shell nanoparticles (Fe@Au) for magnetic drug targeting. J Nanosci Nanotechnol, 2010;10:5527-39.
    • (2010) J Nanosci Nanotechnol , vol.10 , pp. 5527-5539
    • Kayal, S.1    Ramanujan, R.V.2
  • 17
    • 84855268371 scopus 로고    scopus 로고
    • Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population
    • Kim JA, Aberg C, Salvati A, Dawson KA. Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population. Nat Nanotechnol, 2012;7:62-8.
    • (2012) Nat Nanotechnol , vol.7 , pp. 62-68
    • Kim, J.A.1    Aberg, C.2    Salvati, A.3    Dawson, K.A.4
  • 18
    • 0035937595 scopus 로고    scopus 로고
    • Nanoparticulate systems for brain delivery of drugs
    • Kreuter J. Nanoparticulate systems for brain delivery of drugs. Adv Drug Deliv Rev, 2001;47:65-81.
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 65-81
    • Kreuter, J.1
  • 19
    • 33646460828 scopus 로고    scopus 로고
    • The International Congress Series of Drug Transport(ers) and the Diseased Brain, S'Agaro(Girano), Spain
    • Kreuter J. 2005. Application of nanoparticles for the delivery of drugs to the brain, The International Congress Series of Drug Transport(ers) and the Diseased Brain, S'Agaro(Girano), Spain, Vol. 1277, pp. 85-94.
    • (2005) Application of Nanoparticles for the Delivery of Drugs to the Brain , vol.1277 , pp. 85-94
    • Kreuter, J.1
  • 20
    • 0037335187 scopus 로고    scopus 로고
    • Direct evidence that polysor-bate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles
    • Kreuter J, Ramge P, Petrov V, Hamm S, Gelperina SE, Engelhardt B, Alyautdin R, von Briesen H, Begley DJ. Direct evidence that polysor-bate-80- coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles. Pharm Res, 2003;20:409-16.
    • (2003) Pharm Res , vol.20 , pp. 409-416
    • Kreuter, J.1    Ramge, P.2    Petrov, V.3    Hamm, S.4    Gelperina, S.E.5    Engelhardt, B.6    Alyautdin, R.7    Von Briesen, H.8    Begley, D.J.9
  • 22
    • 34547804662 scopus 로고    scopus 로고
    • Immunomodulation by statins: Inhibition of cholesterol vs. isoprenoid biosynthesis
    • Kuipers HF, van den Elsen PJ. Immunomodulation by statins: Inhibition of cholesterol vs. isoprenoid biosynthesis. Biomed Pharmacother, 2007;61:400-7.
    • (2007) Biomed Pharmacother , vol.61 , pp. 400-407
    • Kuipers, H.F.1    Van Den Elsen, P.J.2
  • 23
    • 34249673425 scopus 로고    scopus 로고
    • Plasmonic nanosen-sors for imaging intracellular biomarkers in live cells
    • Kumar S, Harrison N, Richards-Kortum R, Sokolov K. Plasmonic nanosen-sors for imaging intracellular biomarkers in live cells. Nano Lett, 2007;7:1338-43.
    • (2007) Nano Lett , vol.7 , pp. 1338-1343
    • Kumar, S.1    Harrison, N.2    Richards-Kortum, R.3    Sokolov, K.4
  • 24
    • 0033800718 scopus 로고    scopus 로고
    • Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice
    • Laufs U, Gertz K, Huang P, Nickenig G, Bohm M, Dirnagl U, Endres M. Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice. Stroke, 2000;31:2442-9.
    • (2000) Stroke , vol.31 , pp. 2442-2449
    • Laufs, U.1    Gertz, K.2    Huang, P.3    Nickenig, G.4    Bohm, M.5    Dirnagl, U.6    Endres, M.7
  • 25
    • 0942290538 scopus 로고    scopus 로고
    • Atorvastatin reduces neurological deficit and increases synaptogenesis, angiogenesis, and neuronal survival in rats subjected to traumatic brain injury
    • Lu D, Goussev A, Chen J, Pannu P, Li Y, Mahmood A, Chopp M. Atorvastatin reduces neurological deficit and increases synaptogenesis, angiogenesis, and neuronal survival in rats subjected to traumatic brain injury. J Neurotrauma, 2004;21:21-32.
    • (2004) J Neurotrauma , vol.21 , pp. 21-32
    • Lu, D.1    Goussev, A.2    Chen, J.3    Pannu, P.4    Li, Y.5    Mahmood, A.6    Chopp, M.7
  • 26
    • 79959493231 scopus 로고    scopus 로고
    • Characterization of electrospun poly(L-lactide) and gold nanoparticle composite scaffolds for skeletal muscle tissue engineering
    • McKeon-Fischer KD, Freeman JW. Characterization of electrospun poly(L-lactide) and gold nanoparticle composite scaffolds for skeletal muscle tissue engineering. J Tissue Eng Regen Med, 2011;5(7):560-8.
    • (2011) J Tissue Eng Regen Med , vol.5 , Issue.7 , pp. 560-568
    • McKeon-Fischer, K.D.1    Freeman, J.W.2
  • 27
    • 80055102868 scopus 로고    scopus 로고
    • Criteria impacting the cellular uptake of nanoparticles: A study emphasizing polymer type and surfactant effects
    • Musyanovych A, Dausend J, Dass M, Walther P, Mailander V, Landfester K. Criteria impacting the cellular uptake of nanoparticles: A study emphasizing polymer type and surfactant effects. Acta Biomater, 2011;7:4160-8.
    • (2011) Acta Biomater , vol.7 , pp. 4160-4168
    • Musyanovych, A.1    Dausend, J.2    Dass, M.3    Walther, P.4    Mailander, V.5    Landfester, K.6
  • 29
    • 78851469099 scopus 로고    scopus 로고
    • In vivo carotid plaque MRI using quantitative T(2)*measurements with ultrasmall superparamagnetic iron oxide particles: A dose-response study to statin therapy
    • Patterson AJ, Tang TY, Graves MJ, Müller KH, Gillard JH. In vivo carotid plaque MRI using quantitative T(2)*measurements with ultrasmall superparamagnetic iron oxide particles: A dose-response study to statin therapy. NMR Biomed, 2011;24(1):89-95.
    • (2011) NMR Biomed , vol.24 , Issue.1 , pp. 89-95
    • Patterson, A.J.1    Tang, T.Y.2    Graves, M.J.3    Müller, K.H.4    Gillard, J.H.5
  • 31
    • 0034118297 scopus 로고    scopus 로고
    • Polysorbate-80 coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells
    • Ramge P, Unger RE, Oltrogge JB, Zenker D, Begley D, Kreuter J, von Briesen H. Polysorbate-80 coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells. Eur J Neurosci, 2000;12:1931-40.
    • (2000) Eur J Neurosci , vol.12 , pp. 1931-1940
    • Ramge, P.1    Unger, R.E.2    Oltrogge, J.B.3    Zenker, D.4    Begley, D.5    Kreuter, J.6    Von Briesen, H.7
  • 32
    • 78650764375 scopus 로고    scopus 로고
    • Molecularly imprinted nanoparticles with recognition properties towards a laminin H-Tyr-Ile-Gly-Ser-Arg-OH sequence for tissue engineering applications
    • Rosellini E. Barbani N, Giusti P, Ciardelli G, Cristallini C. Molecularly imprinted nanoparticles with recognition properties towards a laminin H-Tyr-Ile-Gly-Ser-Arg-OH sequence for tissue engineering applications. Biomed Mater, 2010;5(6):1-11.
    • (2010) Biomed Mater , vol.5 , Issue.6 , pp. 1-11
    • Rosellini, E.1    Barbani, N.2    Giusti, P.3    Ciardelli, G.4    Cristallini, C.5
  • 33
    • 77958585218 scopus 로고    scopus 로고
    • Synthesis and applications of magnetic nano-particles for biorecognition and point of care medical diagnostics
    • Sandhu A, Handa H, Abe M. Synthesis and applications of magnetic nano-particles for biorecognition and point of care medical diagnostics. Nanotechnology, 2010;21:442001.
    • (2010) Nanotechnology , vol.21 , pp. 442001
    • Sandhu, A.1    Handa, H.2    Abe, M.3
  • 34
    • 0032051840 scopus 로고    scopus 로고
    • Efficacy of oral dalargin-loaded nanoparticle delivery across the blood-brain barrier
    • Schroeder U, Sommerfeld P, Sabel BA. Efficacy of oral dalargin-loaded nanoparticle delivery across the blood-brain barrier. Peptides, 1998;19:777-80.
    • (1998) Peptides , vol.19 , pp. 777-780
    • Schroeder, U.1    Sommerfeld, P.2    Sabel, B.A.3
  • 35
    • 3042656548 scopus 로고    scopus 로고
    • Improvement in neurological outcome after administration of atorvastatin following experimental intracerebral hemorrhage in rats
    • Seyfried D, Han Y, Lu D, Chen J, Bydon A, Chopp M. Improvement in neurological outcome after administration of atorvastatin following experimental intracerebral hemorrhage in rats. J Neurosurg, 2004;101:104-7.
    • (2004) J Neurosurg , vol.101 , pp. 104-107
    • Seyfried, D.1    Han, Y.2    Lu, D.3    Chen, J.4    Bydon, A.5    Chopp, M.6
  • 36
    • 0036964776 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors (statins) in the treatment of Alzheimer's disease and why it would be ill-advise to use one that crosses the blood-brain barrier
    • Sparks DL, Connor DJ, Browne PJ, Lopez JE, Sabbagh MN. HMG-CoA reductase inhibitors (statins) in the treatment of Alzheimer's disease and why it would be ill-advise to use one that crosses the blood-brain barrier. J Nutr Health Aging, 2002;6:324-31.
    • (2002) J Nutr Health Aging , vol.6 , pp. 324-331
    • Sparks, D.L.1    Connor, D.J.2    Browne, P.J.3    Lopez, J.E.4    Sabbagh, M.N.5
  • 38
    • 0032826065 scopus 로고    scopus 로고
    • Neuroprotective properties of statins in cerebral ischemia and stroke
    • Vaughan CJ, Delanty N. Neuroprotective properties of statins in cerebral ischemia and stroke. Stroke, 1999;30:1969-73.
    • (1999) Stroke , vol.30 , pp. 1969-1973
    • Vaughan, C.J.1    Delanty, N.2
  • 39
    • 78449246337 scopus 로고    scopus 로고
    • Lactoferrin-conjugated superparamagnetic iron oxide nanoparticles as a specific MRI contrast agent for detection of brain glioma in vivo
    • Xie H, Zhu Y, Jiang W, Zhou Q, Yang H, Gu N, Zhang Y, Xu H, Xu H, Yang X. Lactoferrin-conjugated superparamagnetic iron oxide nanoparticles as a specific MRI contrast agent for detection of brain glioma in vivo. Biomaterials, 2011;32:495-502.
    • (2011) Biomaterials , vol.32 , pp. 495-502
    • Xie, H.1    Zhu, Y.2    Jiang, W.3    Zhou, Q.4    Yang, H.5    Gu, N.6    Zhang, Y.7    Xu, H.8    Xu, H.9    Yang, X.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.