Neuroprotective effects of angiotensin II type 1 receptor (AT1-R) blocker via modulating AT1-R signaling and decreased extracellular glutamate levels

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 7, 2012, Pages 4099-4110

  Fujita, Tomoyoshi ^a   Hirooka, Kazuyuki ^a   Nakamura, Takehiro ^a   Itano, Toshifumi ^a   Nishiyama, Akira ^a   Nagai, Yukiko ^a   Shiraga, Fumio ^a  

^a KAGAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; APOCYNIN; CANDESARTAN; GLUTAMIC ACID; HYDROETHIDINE; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BENZIMIDAZOLE DERIVATIVE; GLUTAMINE; MESSENGER RNA; NEUTROPHIL CYTOSOL FACTOR 67K; NEUTROPHIL CYTOSOLIC FACTOR 1; PHOSPHOPROTEIN; TETRAZOLE DERIVATIVE;

A WAVE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B WAVE; BIOSENSOR; BLOOD OXYGEN TENSION; CELL SURVIVAL; CONTROLLED STUDY; ELECTRORETINOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; MALE; MICRODIALYSIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; OXYGEN ELECTRODE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; RETINA GANGLION CELL; RETINA ISCHEMIA; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; UPREGULATION; VITREOUS BODY; ANIMAL; BIOSYNTHESIS; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; EXTRACELLULAR FLUID; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RETINA; RETINA DISEASE; SPRAGUE DAWLEY RAT;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BENZIMIDAZOLES; CELL SURVIVAL; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; EXTRACELLULAR FLUID; GENE EXPRESSION REGULATION; GLUTAMINE; IMMUNOHISTOCHEMISTRY; MALE; NADPH OXIDASE; PHOSPHOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; REPERFUSION INJURY; RETINA; RETINAL DISEASES; RETINAL GANGLION CELLS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TETRAZOLES; VITREOUS BODY;

EID: 84871393226     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-9167     Document Type: Article

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