Leukotriene A4 hydrolase haplotype, diet and atherosclerosis: A twin study

Atherosclerosis

Volumn 226, Issue 1, 2013, Pages 238-244

  Zhao, Jinying ^a   Goldberg, Jack ^b   Vaccarino, Viola ^c  

^a TULANE UNIVERSITY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

Carotid atherosclerosis; Gene diet interaction; Leukotriene haplotype; Twin study

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN 5; LEUKOTRIENE A4 HYDROLASE; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG;

ADULT; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CAUCASIAN; CLINICAL ASSESSMENT; DIET; DIETARY INTAKE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HAPLOTYPE; HEART PROTECTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TWINS;

ATHEROSCLEROSIS; DIET; DISEASES IN TWINS; EPOXIDE HYDROLASES; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED;

EID: 84871391059     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.10.048     Document Type: Article

References (36)

1. Jala V.R., Haribabu B. Leukotrienes and atherosclerosis: new roles for old mediators. Trends Immunol 2004, 25(6):315-322.
2. Helgadottir A., Manolescu A., Thorleifsson G., et al. The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet 2004, 36(3):233-239.
3. Helgadottir A., Manolescu A., Helgason A., et al. A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genet 2006, 38(1):68-74.
4. Crosslin D.R., Shah S.H., Nelson S.C., et al. Genetic effects in the leukotriene biosynthesis pathway and association with atherosclerosis. Hum Genet 2009, 125(2):217-229.
5. Dwyer J.H., Allayee H., Dwyer K.M., et al. Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis. N Engl J Med 2004, 350(1):29-37.
6. Allayee H., Baylin A., Hartiala J., et al. Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction. Am J Clin Nutr 2008, 88(4):934-940.
7. James M.J., Gibson R.A., Cleland L.G. Dietary polyunsaturated fatty acids and inflammatory mediator production. Am J Clin Nutr 2000, 71(Suppl. 1):343S-348S.
8. Kris-Etherton P.M., Harris W.S., Appel L.J. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002, 106(21):2747-2757.
9. Harris W.S., Mozaffarian D., Rimm E., et al. Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Circulation 2009, 119(6):902-907.
10. Simopoulos A.P. The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp Biol Med (Maywood) 2008, 233(6):674-688.
11. Sacks F.M., Campos H. Polyunsaturated fatty acids, inflammation, and cardiovascular disease: time to widen our view of the mechanisms. J Clin Endocrinol Metab 2006, 91(2):398-400.
12. Henderson W.R. The role of leukotrienes in inflammation. Ann Intern Med 1994, 121(9):684-697.
13. Zhao J., Cheema F.A., Bremner J.D., et al. Heritability of carotid intima-media thickness: a twin study. Atherosclerosis 2008, 197(2):814-820.
14. Vaccarino V., Brennan M.L., Miller A.H., et al. Association of major depressive disorder with serum myeloperoxidase and other markers of inflammation: a twin study. Biol Psychiatry 2008, 64(6):476-483.
15. Goldberg J., Curran B., Vitek M.E., et al. The Vietnam Era twin registry. Twin Res 2002, 5(5):476-481.
16. Scherrer J.F., Xian H., Bucholz K.K., et al. A twin study of depression symptoms, hypertension, and heart disease in middle-aged men. Psychosom Med 2003, 65(4):548-557.
17. Simon A., Gariepy J., Chironi G., et al. Intima-media thickness: a new tool for diagnosis and treatment of cardiovascular risk. J Hypertens 2002, 20(2):159-169.
18. Willett W. Food frequency methods. Nutritional epidemiology 1998, 74-91. Oxford University Press, New York, NY.
19. Richardson M.T., Ainsworth B.E., Wu H.C., et al. Ability of the Atherosclerosis Risk in Communities (ARIC)/Baecke Questionnaire to assess leisure-time physical activity. Int J Epidemiol 1995, 24(4):685-693.
20. Consortium T.I.H. A haplotype map of the human genome. Nature 2005, 437:1299-1320.
21. Helgadottir A., Gretarsdottir S., St Clair D., et al. Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population. Am J Hum Genet 2005, 76(3):505-509.
22. Stephens M., Smith N.J., Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001, 68(4):978-989.
23. Pischon T., Hankinson S.E., Hotamisligil G.S., et al. Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women. Circulation 2003, 108(2):155-160.
24. Sekikawa A., Kadowaki T., El-Saed A., et al. Differential association of docosahexaenoic and eicosapentaenoic acids with carotid intima-media thickness. Stroke 2011, 42(9):2538-2543.
25. Lindqvist H.M., Sandberg A.S., Fagerberg B., et al. Plasma phospholipid EPA and DHA in relation to atherosclerosis in 61-year-old men. Atherosclerosis 2009, 205(2):574-578.
26. Benjamin Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Roy Stat Soc B (Methodological) 1995, 57(1):289-300.
27. Zhao J., Quyyumi A.A., Patel R., et al. Sex-specific association of depression and a haplotype in leukotriene A4 hydrolase gene. Psychosom Med 2009, 71(7):691-696.
28. Snelgrove R.J. Leukotriene A4 hydrolase: an anti-inflammatory role for a proinflammatory enzyme. Thorax 2011, 66(6):550-551.
29. Snelgrove R.J., Jackson P.L., Hardison M.T., et al. A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation. Science 2010, 330(6000):90-94.
30. Harris W.S., O'Keefe J.H. Preventive use of N-3 fatty acids. Circulation 2003, 108(19):e139. author reply e139.
31. Linsel-Nitschke P., Gotz A., Medack A., et al. Genetic variation in the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) is associated with myocardial infarction in the German population. Clin Sci (Lond) 2008, 115(10):309-315.
32. Tsai A.K., Li N., Hanson N.Q., et al. Associations of genetic polymorphisms of arachidonate 5-lipoxygenase-activating protein with risk of coronary artery disease in a European-American population. Atherosclerosis 2009, 207(2):487-491.
33. Girelli D., Martinelli N., Trabetti E., et al. ALOX5AP gene variants and risk of coronary artery disease: an angiography-based study. Eur J Hum Genet 2007, 15(9):959-966.
34. Lohmussaar E., Gschwendtner A., Mueller J.C., et al. ALOX5AP gene and the PDE4D gene in a central European population of stroke patients. Stroke 2005, 36(4):731-736.
35. Zee R.Y., Cheng S., Hegener H.H., et al. Genetic variants of arachidonate 5-lipoxygenase-activating protein, and risk of incident myocardial infarction and ischemic stroke: a nested case-control approach. Stroke 2006, 37(8):2007-2011.
36. Meschia J.F., Brott T.G., Brown R.D., et al. Phosphodiesterase 4D and 5-lipoxygenase activating protein in ischemic stroke. Ann Neurol 2005, 58(3):351-361.