Effects of total flavonoids from Dracocephalum moldavica on the proliferation, migration, and adhesion molecule expression of rat vascular smooth muscle cells induced by TNF-α

Pharmaceutical Biology

Volumn 51, Issue 1, 2013, Pages 74-83

  Xing, Jianguo ^a   Peng, Kejun ^b   Cao, Wenjiang ^c   Lian, Xuhui ^b   Wang, Qiulin ^b   Wang, Xinchun ^c  

^a Xinjiang Institute of Materia Medica   (China)

^b CHENGDU MEDICAL COLLEGE   (China)

^c SHIHEZI UNIVERSITY   (China)

Author keywords

Anti inflammatory activity; Atherosclerosis; VSMC

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; FLAVONOID; INTERCELLULAR ADHESION MOLECULE 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR ADHESION PROTEIN 1;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRACOCEPHALUM MOLDAVICA; IMMUNOHISTOCHEMISTRY; LAMIACEAE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; GENE EXPRESSION REGULATION; INHIBITORY CONCENTRATION 50; LAMIACEAE; MEDICINE, CHINESE TRADITIONAL; MUSCLE, SMOOTH, VASCULAR; PLANT COMPONENTS, AERIAL; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

DRACOCEPHALUM MOLDAVICA; LAMIACEAE; RATTUS;

EID: 84871384353     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2012.711839     Document Type: Article

References (32)

1. Benavente-Garcia O, Castillo J. (2008). Update on uses and properties of citrus flavonoids: New findings in anticancer, cardiovascular, and anti-inflammatory activity. J Agric Food Chem, 56, 6185-6205
2. Brasier AR. (2010). The nuclear factor-κB-interleukin-6 signalling pathway mediating vascular inflammation. Cardiovasc Res, 86, 211-218
3. Braun M, Pietsch P, Schror K, Baumann G, Felix SB. (1999). Cellular adhesion molecules on vascular smooth muscle cells. Cardiovasc Res, 41, 395-401 (Pubitemid 29087336)
4. Choi KW, Park HJ, Jung DH, Kim TW, Park YM, Kim BO, Sohn EH, Moon EY, Um SH, Rhee DK, Pyo S. (2010). Inhibition of TNF-α-induced adhesion molecule expression by diosgenin in mouse vascular smooth muscle cells via downregulation of the MAPK, Akt and NF-κB signaling pathways. Vascul Pharmacol, 53, 273-280
5. El Haouari M, Rosado JA. (2011). Modulation of platelet function and signaling by flavonoids. Mini Rev Med Chem, 11, 131-142
6. Geleijnse JM, Launer LJ, Hofman A, Pols HA, Witteman JC. (1999). Tea flavonoids may protect against atherosclerosis: The Rotterdam Study. Arch Intern Med, 159, 2170-2174 (Pubitemid 29483156)
7. Gerthoffer WT. (2007). Mechanisms of vascular smooth muscle cell migration. Circ Res, 100, 607-621 (Pubitemid 46594875)
8. Glass CK, Witztum JL. (2001). Atherosclerosis. the road ahead. Cell, 104, 503-516
9. Gonzalez R, Ballester I, Lopez-Posadas R, Suarez MD, Zarzuelo A, Martinez-Augustin O, Sanchez de Medina F. (2011). Effects of flavonoids and other polyphenols on inflammation. Crit Rev Food Sci Nutr, 51, 331-362
10. Grassi D, Desideri G, Croce G, Tiberti S, Aggio A, Ferri C. (2009). Flavonoids, vascular function and cardiovascular protection. Curr Pharm Des, 15, 1072-1084
11. Gu HF, Chen RY, Sun YH, Xing JG. (2005). Studies on chemical constituents in herbs of Dracocephalum moldavica II. Zhongguo Zhong Yao Za Zhi, 30, 677-679
12. Guo CM, Wu RL, Feng S, Wang JD. (2005). Extraction and determination of Dracocephalum moldavica polysaccharides and its effects on reducing the free radical oxygen (in Chinese). Shi Pin Yu Fa Jiao Gong Ye 31, 129-132
13. Hansson GK. (2005). Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med, 352, 1685-1695
14. Hope SA, Meredith IT. (2003). Cellular adhesion molecules and cardiovascular disease. Part I. Their expression and role in atherogenesis. Intern Med J, 33, 380-386 (Pubitemid 37082800)
15. Huo Y, Ley K. (2001). Adhesion molecules and atherogenesis. Acta Physiol Scand, 173, 35-43 (Pubitemid 32948331)
16. Kasper HU, Schmidt A, Roessner A. (1996). Expression of the adhesion molecules ICAM, VCAM, and ELAM in the arteriosclerotic plaque. Gen Diagn Pathol, 141, 289-294 (Pubitemid 26167120)
17. Kim HJ, Yoo EK, Kim JY, Choi YK, Lee HJ, Kim JK, Jeoung NH, Lee KU, Park IS, Min BH, Park KG, Lee CH, Aronow BJ, Sata M, Lee IK. (2009). Protective role of clusterin/apolipoprotein J against neointimal hyperplasia via antiproliferative effect on vascular smooth muscle cells and cytoprotective effect on endothelial cells. Arterioscler Thromb Vasc Biol, 29, 1558-1564
18. Lee B, Lee EJ, Kim DI, Park SK, Kim WJ, Moon SK. (2009). Inhibition of proliferation and migration by piceatannol in vascular smooth muscle cells. Toxicol In Vitro, 23, 1284-1291
19. Li JP, Li F, Guo WB, Zhou QZ, Liu CD, Mao XM, Tan WL, Zheng SB. (2010). Efficacy of low-dose tadalafil on ED assessed by Self- Esteem and Relationship Questionnaire. Zhonghua Nan Ke Xue, 16, 1147-1149
20. Libby P, Okamoto Y, Rocha VZ, Folco E. (2010). Inflammation in atherosclerosis: Transition from theory to practice. Circ J, 74, 213-220
21. Lusis AJ. (2000). Atherosclerosis. Nature, 407, 233-241
22. MacKenzie CJ, Ritchie E, Paul A, Plevin R. (2007). IKKα and IKKβ function in TNFα-stimulated adhesion molecule expression in human aortic smooth muscle cells. Cell Signal, 19, 75-80 (Pubitemid 44883366)
23. McKellar GE, McCarey DW, Sattar N, McInnes IB. (2009). Role for TNF in atherosclerosis? Lessons from autoimmune disease. Nat Rev Cardiol, 6, 410-417
24. Osterud B, Bjorklid E. (2003). Role of monocytes in atherogenesis. Physiol Rev, 83, 1069-1112 (Pubitemid 37222268)
25. Rajesh M, Mukhopadhyay P, Hasko G, Huffman JW, Mackie K, Pacher P. (2008). CB2 cannabinoid receptor agonists attenuate TNF-α- induced human vascular smooth muscle cell proliferation and migration. Br J Pharmacol, 153, 347-357
26. Ranganna K, Yatsu FM, Hayes BE, Milton SG, Jayakumar A. (2000). Butyrate inhibits proliferation-induced proliferating cell nuclear antigen expression (PCNA) in rat vascular smooth muscle cells. Mol Cell Biochem, 205, 149-161 (Pubitemid 30216799)
27. Reed J. (2002). Cranberry flavonoids, atherosclerosis and cardiovascular health. Crit Rev Food Sci Nutr, 42, 301-316
28. Song R, Roberts BL, Lee EO, Lam P, Bae SC. (2010). A randomized study of the effects of t'ai chi on muscle strength, bone mineral density, and fear of falling in women with osteoarthritis. J Altern Complement Med, 16, 227-233
29. Tedgui A, Mallat Z. (2006). Cytokines in atherosclerosis: Pathogenic and regulatory pathways. Physiol Rev, 86, 515-581
30. Terao J. (2009). Dietary flavonoids as antioxidants. Forum Nutr, 61, 87-94
31. Wajant H, Pfizenmaier K, Scheurich P. (2003). Tumor necrosis factor signaling. Cell Death Differ, 10, 45-65 (Pubitemid 36511832)
32. Yamamoto Y, Gaynor RB. (2001). Role of the NF-κB pathway in the pathogenesis of human disease states. Curr Mol Med, 1, 287-296 (Pubitemid 33773312)