What are the opportunities for EEG-based monitoring of delirium in the ICU?

Journal of Neuropsychiatry and Clinical Neurosciences

Volumn 24, Issue 4, 2012, Pages 472-477

  van der Kooi, Arendina W ^a   Leijten, Frans S S ^a   van der Wekken, Ruben J ^a   Slooter, Arjen J C ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA RHYTHM; ARTICLE; CONTROLLED STUDY; DELIRIUM; DELTA RHYTHM; DEMENTIA; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; ELDERLY CARE; ELECTROENCEPHALOGRAM; HUMAN; INTENSIVE CARE; MAJOR CLINICAL STUDY; NEUROMONITORING; PARKINSON DISEASE; POSTERIOR PARIETAL CORTEX; PRIORITY JOURNAL; THETA RHYTHM;

EID: 84871354696     PISSN: 08950172     EISSN: 15457222     Source Type: Journal    
DOI: 10.1176/appi.neuropsych.11110347     Document Type: Article

References (38)

1. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision. Washington, DC, American Psychiatric Association, 2000
2. Ely EW, Shintani AK, Truman B, et al: Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA 2004; 291:1753-1762
3. Girard TD, Kress JP, Fuchs BD, et al: Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled Trial): a randomised, controlled trial. Lancet 2008; 371:126-134
4. Jackson JC, Hart RP, Gordon SM, et al: Six-month neuropsychological outcome of medical intensive care unit patients. Crit Care Med 2003; 31:1226-1234
5. Pisani MA, Kong SYJ, Kasl SV, et al: Days of delirium are associated with 1-year mortality in an older intensive care unit population. Am J Respir Crit Care Med 2009; 180:1092-1097
6. Thomason JW, Shintani A, Peterson JF, et al: Intensive care unit delirium is an independent predictor of longer hospital stay: a prospective analysis of 261 non-ventilated patients. Crit Care 2005; 9:R375-R381
7. Milbrandt EB, Deppen S, Harrison PL, et al: Costs associated with delirium in mechanically ventilated patients. Crit Care Med 2004; 32:955-962
8. van den Boogaard M, Schoonhoven L, Evers AW, et al: Delirium in critically ill patients: impact on long-term healthrelated quality of life and cognitive functioning. Crit Care Med 2012; 40:112-118
9. van Eijk MMJ, van Marum RJ, Klijn IAM, et al: Comparison of delirium assessment tools in a mixed intensive care unit. Crit Care Med 2009; 37:1881-1885
10. American Psychiatric Association: Practice guideline for the treatment of patients with delirium. Am J Psychiatry 1999; 156 (Suppl):1-20
11. Jacobi J, Fraser GL, Coursin DB, et al; Task Force of the American College of Critical Care Medicine (ACCM) of the Society of Critical Care Medicine (SCCM), American Society of Health-System Pharmacists (ASHP), American College of Chest Physicians: Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med 2002; 30:119-141
12. Ely EW, Margolin R, Francis J, et al: Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med 2001; 29:1370-1379
13. van Eijk MM, van den Boogaard M, van Marum RJ, et al: Routine use of the Confusion Assessment Method for the intensive care unit: a multicenter study. Am J Respir Crit Care Med 2011; 184:340-344
14. Heymann A, Radtke F, Schiemann A, et al: Delayed treatment of delirium increases mortality rate in intensive care unit patients. J Int Med Res 2010; 38:1584-1595
15. Jacobson SA, Leuchter AF, Walter DO: Conventional and quantitative EEG in the diagnosis of delirium among the elderly. J Neurol Neurosurg Psychiatry 1993; 56:153-158
16. Hirsch LJ: Continuous EEG monitoring in the intensive care unit: an overview. J Clin Neurophysiol 2004; 21:332-340
17. Palanca BJ, Mashour GA, Avidan MS: Processed electroencephalogram in depth of anesthesia monitoring. Curr Opin Anaesthesiol 2009; 22:553-559
18. Friedman D, Hirsch LJ: Diagnosing and monitoring seizures in the ICU: the role of continuous EEG for detection and management of seizures in critically ill patients, in Seizures in Critical Care. Edited by Varelas P. New York, Humana Press, 2010, pp 21-47
19. Jacobson SA, Leuchter AF, Walter DO, et al: Serial quantitative EEG among elderly subjects with delirium. Biol Psychiatry 1993; 34:135-140
20. Ely EW, Truman B, Manzi DJ, et al: Consciousness monitoring in ventilated patients: bispectral EEG monitors arousal not delirium. Intensive Care Med 2004; 30:1537-1543
21. Koponen H, Partanen J, Pääkkönen A, et al: EEG spectral analysis in delirium. J Neurol Neurosurg Psychiatry 1989; 52:980-985
22. Thomas C, Hestermann U, Walther S, et al: Prolonged activation EEG differentiates dementia with and without delirium in frail elderly patients. J Neurol Neurosurg Psychiatry 2008; 79:119-125
23. Thomas C, Hestermann U, Kopitz J, et al: Serum anticholinergic activity and cerebral cholinergic dysfunction: an EEG study in frail elderly with and without delirium. BMC Neurosci 2008; 9:86-95
24. Katz IR, Mossey J, Sussman N, et al: Bedside clinical and electrophysiological assessment: assessment of change in vulnerable patients. Int Psychogeriatr 1991; 3:289-300
25. Katz IR, Curyto KJ, TenHave T, et al: Validating the diagnosis of delirium and evaluating its association with deterioration over a one-year period. Am J Geriatr Psychiatry 2001; 9:148-159
26. Matsushima E, Nakajima K, Moriya H, et al: A psychophysiological study of the development of delirium in coronary care units. Biol Psychiatry 1997; 41:1211-1217
27. Reischies FM, Neuhaus AH, Hansen ML, et al: Electrophysiological and neuropsychological analysis of a delirious state: the role of the anterior cingulate gyrus. Psychiatry Res 2005; 138:171-181
28. Trzepacz PT, Brenner RP, Coffman G, et al: Delirium in liver transplantation candidates: discriminant analysis of multiple test variables. Biol Psychiatry 1988; 24:3-14
29. Trzepacz PT, Sclabassi RJ, Van Thiel DH: Delirium: a subcortical phenomenon? J Neuropsychiatry Clin Neurosci 1989; 1:283-290
30. Plaschke K, Hill H, Engelhardt R, et al: EEG changes and serum anticholinergic activity measured in patients with delirium in the intensive care unit. Anaesthesia 2007; 62:1217-1223
31. Plaschke K, Fichtenkamm P, Schramm C, et al: Early postoperative deliriumafter open-heart cardiac surgery is associated with decreased bispectral EEG and increased cortisol and interleukin-6. Intensive Care Med 2010; 36:2081-2089
32. Rechtschaffen A, Kales A: A Manual of Standardized Terminology, Techniques, and Scoring System for Sleep Stages of Human Subjects. Washington, DC, U.S. Government Printing Office, 1968
33. Pisani MA, Redlich CA, McNicoll L, et al: Short-term outcomes in older intensive care unit patients with dementia. Crit Care Med 2005; 33:1371-1376
34. van den Boogaard M, Pickkers P, Slooter AJC, et al: Development and validation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for intensive care patients: observational multicentre study. BMJ 2012; 344:e420
35. Richardson SS, Sullivan G, Hill A, et al: Use of aggressive medical treatments near the end of life: differences between patients with and without dementia. Health Serv Res 2007; 42:183-200
36. Liem-Moolenaar M, Gray FA, de Visser SJ, et al: Psychomotor and cognitive effects of a single oral dose of talnetant (SB223412) in healthy volunteers compared with placebo or haloperidol. J Psychopharmacol 2010; 24:73-82
37. Yoshimura M, Koenig T, Irisawa S, et al: A pharmaco-EEG study on antipsychotic drugs in healthy volunteers. Psychopharmacology (Berl) 2007; 191:995-1004
38. McClelland GR, Cooper SM, Pilgrim AJ: A comparison of the central nervous system effects of haloperidol, chlorpromazine, and sulpiride in normal volunteers. Br J Clin Pharmacol 1990; 30:795-803