A pharmaco-EEG study on antipsychotic drugs in healthy volunteers

Psychopharmacology

Volumn 191, Issue 4, 2007, Pages 995-1004

  Yoshimura, Masafumi ^a,b   Koenig, Thomas ^a   Irisawa, Satoshi ^b   Isotani, Toshiaki ^b,c   Yamada, Keizo ^b   Kikuchi, Mitsuru ^a,d   Okugawa, Gaku ^b   Yagyu, Takami ^b,e   Kinoshita, Toshihiko ^b   Strik, Werner ^a   Dierks, Thomas ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b KANSAI MEDICAL UNIVERSITY   (Japan)

^c Japan Labour Health and Welfare Organization   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

^e Neyagawa Sanatorium ^*  (Japan)

Author keywords

Chlorpromazine; Haloperidol; Key lock principle; Microstates; Olanzapine; Perospirone; Pharmaco EEG; Quetiapine; Risperidone; Schizophrenia

Indexed keywords

CHLORPROMAZINE; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; PEROSPIRONE; PLACEBO; QUETIAPINE; RISPERIDONE;

ADULT; ARTICLE; CLUSTER ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; ELECTRODE; ELECTROENCEPHALOGRAPHY; GRAVITY; HUMAN; HUMAN EXPERIMENT; MALE; MENTAL HEALTH; NORMAL HUMAN; PRIORITY JOURNAL;

ADULT; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; CHLORPROMAZINE; CROSS-OVER STUDIES; DIBENZOTHIAZEPINES; ELECTROENCEPHALOGRAPHY; FOURIER ANALYSIS; HALOPERIDOL; HUMANS; INDOLES; MALE; REFERENCE VALUES; RISPERIDONE; SINGLE-BLIND METHOD; THIAZOLES; TIME FACTORS;

EID: 33947101505     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-007-0737-8     Document Type: Article

References (43)

1. Borbely AA, Achermann P (1999) Sleep homeostasis and models of sleep regulation. J Biol Rhythms 14:557-568
2. de Paulis T (2002) Perospirone (Sumitomo Pharmaceuticals). Curr Opin Investig Drugs 3:121-129
3. Dierks T, Strik WK, Maurer K (1995) Electrical brain activity in schizophrenia described by equivalent dipoles of FFT-data. Schizophr Res 14:145-154
4. Farde L, Nordstroem AL, Wiesel FA, Pauli S, Halldin C, Sedvall G (1992) Positron emission tomographic analysis of central D1- and D2- dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine: relation to extrapyramidal side effects. Arch Gen Psychiatry 49:538-544
5. Fink M (1968) EEG classification of psychoactive compounds in man: review and therapy of behavioral associations. In: Efron DH, Cole JO (eds) Psychopharmacology: a review of progress 1957-1967. US Government Printing Office, Washington, pp 497-507
6. Galderisi S, Mucci A, Bucci P, Mignone ML, Maj M (1996) Multilead quantitative EEG profile of clozapine in resting and vigilance-controlled conditions. Psychiatry Res 67:113-122
7. Hubl D, Kleinlogel H, Froelich L, Weinandi T, Maurer K, Holstein W, Czekalla J, Dierks T (2001) Multilead quantitative electroencephalogram profile and cognitive evoked potentials (P300) in healthy subjects after a single dose of olanzapine. Psychopharmacology 158:281-288
8. Hughes JR, John ER (1999) Conventional and quantitative electroencephalography in psychiatry. J Neuropsychiatry Clin Neurosci 11:190-208
9. Isotani T, Tanaka H, Lehmann D, Pascual-Marqui RD, Kochi K, Saito N, Yagyu T, Kinoshita T, Sasada K (2001) Source localization of EEG activity during hypnotically induced anxiety and relaxation. Int J Psychophysiol 41:143-153
10. Itil TM (1961) Electroencephalographische Befunde zur Klassifikation neuro- und thymoleptischer Medikamente. Med Exp 5:347-363
11. Itil TM, Saletu B, Davis S (1972) EEG findings in chronic schizophrenics based on digital computer period analysis and analog power spectra. Biol Psychiatry 5:1-13
12. John ER, Ahn H, Prichep LS, Trepetin M, Brown D, Kaye H (1980) Developmental equations for the electroencephalogram. Science 210:1255-1258
13. Kasper S, Tauscher J, Willeit M, Stamenkovic M, Neumeister A, Kuefferle B, Barnas C, Stastny J, Praschak-Rieder N, Pezawas L, de Zwaan M, Quiner S, Pirker W, Asenbaum S, Podreka I, Bruecke T (2002) Receptor and transporter imaging studies in schizophrenia, depression, bulimia and Tourette's disorder: implications for psychopharmacology. World J Biol Psychiatry 3:133-146
14. Kato T, Hirose A, Ohno Y, Shimuzu H, Tanaka H, Nakamura M (1990) Binding profile of SM-9018, a novel antipsychotic candidate. Jpn J Pharmacol 54:478-481
15. Koenig T, Lehmann D, Merlo MCG, Kochi K, Hell D, Koukkou M (1999) A deviant EEG brain microstate in acute, neuroleptic-naïve schizophrenics at rest. Eur Arch Psychiatry Clin Neurosci 249:205-211
16. Koenig T, Prichep L, Lehmann D, Sosa PV, Braeker E, Kleinlogel H, Isenhart R, John ER (2002) Millisecond and millisecond, year by year: normative EEG microstates and developmental stages. NeuroImage 16:41-48
17. Kubicki S, Herrmann WM, Fichte K, Freund G (1979) Reflections on the topics: EEG frequency bands and regulation of vigilance. Pharmakopsychiatr Neuropsychopharmakol 12:237-245
18. Lehmann D, Michel CM (1989) Intracerebral dipole sources of EEG FFT power maps. Brain Topogr Fall-Winter 2:155-164 (erratum in: Brain Topogr 1990 Summer 2:311)
19. Lehmann D and Skrandies W (1980) Reference-free identification of components of checkerboard-evoked multichannel potential fields. Electroencephalogr Clin Neurophysiol 48:609-621
20. Lehmann D, Ozaki H, Pal I (1987) EEG alpha map series: brain micro-states by space-oriented adaptive segmentation. Electroencephalogr Clin Neurophysiol 67:271-288
21. Lehmann D, Faber PL, Galderisi S, Hermann WM, Kinoshita T, Koukkou M, Mucci A, Pascual-Marqui RD, Saito N, Wackermann J, Winterer G, Koenig T (2005) EEG microstate duration and syntax in acute, medication-naïve, first-episode schizophrenia: a multi-center study. Psychiatry Res 138:141-156
22. Manly BFJ (1991) Randomization and Monte Carlo methods in biology. Chapman and Hall, London
23. Mucci A, Volpe U, Merlotti E, Bucci P, Galderisi S (2006) Pharmaco-EEG in psychiatry. Clin EEG Neurosci 37:81-98
24. Mueller TJ, Koenig T, Wackermann J, Kalus P, Fallgatter A, Strik WK, Lehmann D (2005) Subsecond changes of global brain state in illusory multistable motion perception. J Neural Transm 112:565-576
25. Ozaki H, Lehmann D (2000) EEG reconsidered: from neuroelectric signals to human conscious experience. Jpn J Clin Neurophysiol 28:15-17
26. Pascual-Marqui RD, Michel CM, Lehmann D (1994) Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain. Int J Psychophysiol 18:49-65
27. Pascual-Marqui RD, Michel CM, Lehmann D (1995) Segmentation of brain electrical activity into microstates: model estimation and validation. IEEE Trans Biomed Eng 42:658-665
28. Pascual-Marqui RD, Lehmann D, Koenig T (1999) Low resolution brain electromagnetic tomography (LORETA) functional imaging in acute, neuroleptic-naive, first-episode, productive schizophrenia. Psychiatry Res 30:169-179
29. Saito M, Kagono Y, Suitsu N, Yamamoto Y, Kinoshita T, Ohya D, Fukui Y, Hashimoto C (1983) A study on anti-psychotic drugs by the aid of quantitative EEG and multivariate analysis-doses and action trait of haloperidol. Jpn J Neuropsychopharmacol 5:843-856
30. Saito N, Okajima Y, Isotani T, Yagyu T, Nobuhara K, Nishimura T, Fukushima M, Kuginuki T, Kinoshita T, Saito M (1993) Early prediction and orientation of the clinical effects of a new antipsychotic compound, risperidone, in human: a quantitative pharmaco-EEG study. Jpn J Neuropsychopharmacol 15:693-703
31. Saito A, Kuginuki T, Fukushima M, Saito M (1998) Pharmaco-EEG study of perospirone, a D2 and 5-HT2 antagonist, in healthy male volunteers. Jpn J EEG EMG 26:205-215
32. Saletu B (1980) Central measures in schizophrenia. In: Van Praag HM, Lader MH, Rafaelsen OJ, Sachar EJ (eds) Handbook of biological psychiatry part II. Brain mechanisms and abnormal behavior - psychophysiology. Marcel Dekker, New York, pp 97-144
33. Saletu B (1987) The use of pharmaco-EEG in drug profiling. In: Hindmarch I, Stonier PD (eds) Human psychopharmacology: measures and methods, vol 1. Wiley, Chichester, pp 172-200
34. Saletu B, Kuefferle B, Gruenberger J, Anderer P (1986) Quantitative EEG, SPEM, and psychometric studies in schizophrenics before and during differential neuroleptic therapy. Pharmacopsychiatry 19:434-437
35. Saletu B, Anderer P, Kinsperger K, Gruenberger J (1987) Topographic brain mapping of EEG in neuropsychopharmacology: part II. Clinical applications (pharmaco EEG imaging). Methods Find Exp Clin Pharmacol 9:385-408
36. Saletu B, Anderer P, Saletu-Zyhlarz GM, Pascual-Marqui RD (2002) EEG topography and tomography in diagnosis and treatment of mental disorders: evidence for a key-lock principle. Methods Find Exp Clin Pharmacol 24(Suppl D):97-106
37. Saletu-Zyhlarz GM, Anderer P, Berger P, Gruber G, Oberndorfer S, Saletu B (2000) Nonorganic insomnia in panic disorder: comparative sleep laboratory studies with normal controls and placebo-controlled trials with alprazolam. Hum Psychopharmacol 15:241-254
38. Shiwa T, Amano T, Matsubayashi H, Seki T, Sasa M, Sakai N (2003) Perospirone, a novel antipsychotic agent, hyperpolarizes rat dorsal raphe neurons via 5-HT1A receptor. J Pharmacol Sci 93:114-117
39. Stahl SM (2000) Antypsychotic agents. In: Essential psychopharmacology: neuroscientific basis and practical applications, 2nd edn. Cambridge University Press, Cambridge, pp 401-458
40. Strelets V, Faber PL, Golikova J, Novototsky-Vlasov V, Koenig T, Gianotti LRR, Gruzelier JH, Lehmann D (2003) Chronic schizophrenics with positive symptomatology have shortened EEG microstate durations. Clin Neurophysiol 114:2043-2051
41. Strik WK, Lehmann D (1993) Data-determined window size and space-oriented segmentation of spontaneous EEG map series. Electroencephalogr Clin Neurophysiol 87:169-174
42. Strik WK, Fallgatter AJ, Brandeis D, Pascual-Marqui RD (1998) Three-dimensional tomography of event-related potentials during response inhibition: evidence for phasic frontal lobe activation. Electroencephalogr Clin Neurophysiol 108:406-413
43. Wackermann J, Lehmann D, Michel CM, Strik WK (1993) Adaptive segmentation of spontaneous EEG map series into spatially defined microstates. Int J Psychophysiol 14:269-283