Unique In Vitro and In Vivo Thrombopoietic Activities of Ingenol 3,20 Dibenzoate, A Ca++-Independent Protein Kinase C Isoform Agonist

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Racke, Frederick K ^a,b   Baird, Maureen ^a   Barth, Rolf F ^a   Huo, Tianyao ^a,c   Yang, Weilian ^a   Gupta, Nilendu ^a   Weldon, Michael ^a   Rutledge, Heather ^a,b  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CD34 ANTIGEN; HEMATOLOGIC AGENT; INGENOL 3,20 DIBENZOATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL STIMULATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEMATOPOIETIC CELL; HEMOGLOBIN DETERMINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE COUNT; MEGAKARYOCYTE; MEGAKARYOPOIESIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; THROMBOCYTE COUNT; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS;

ANIMALS; ANTIGENS, CD34; BIOLOGICAL MARKERS; BLOOD PLATELETS; CALCIUM; CELL PROLIFERATION; DITERPENES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; ISOENZYMES; MEGAKARYOCYTES; MICE; PROTEIN KINASE C; STEM CELLS; THROMBOPOIESIS;

MUS;

EID: 84871351211     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051059     Document Type: Article

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