Prior and concurrent administration of recombinant human megakaryocyte growth and development factor in patients receiving consolidation chemotherapy for de novo acute myeloid leukemia - A randomized, placebo-controlled, double-blind safety and efficacy study

Annals of Hematology

Volumn 82, Issue 11, 2003, Pages 677-683

  Geissler, K ^a   Liu Yin, J A ^b   Ganser, A ^c   Sanz, M A ^d   Szer, J ^e   Raghavachar, A ^f   Hoelzer, D ^g   Martinez, C ^h   Taylor, K ⁱ   Kanz, L ^j   To, L B ^k   Archimbaud, E ^l  

^a GENERAL HOSPITAL LINZ   (Austria)

^b MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d HOSPITAL UNIVERSITARIO LA FE   (Spain)

^e ROYAL MELBOURNE HOSPITAL   (Australia)

^f HELlOS Klinikum Wuppertal   (Germany)

^g GOETHE UNIVERSITY   (Germany)

^h HOSPITAL CLÍNIC   (Spain)

ⁱ Mater Hospital   (Australia)

^j UNIVERSITY OF TÜBINGEN   (Germany)

^k HANSON INSTITUTE   (Australia)

^l EDOUARD HERRIOT HOSPITAL   (France)

more..

Author keywords

AML; Chemotherapy; MGDF; Thrombocytopenia

Indexed keywords

ANTINEOPLASTIC AGENT; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; GRANULOCYTE COLONY STIMULATING FACTOR; HEPARIN; MACROGOL; MITOXANTRONE; PLACEBO; RECOMBINANT MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; RECOMBINANT THROMBOPOIETIN;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; BLEEDING; BRAIN HEMORRHAGE; CLINICAL OBSERVATION; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DESIGN; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; EPISTAXIS; FEMALE; HEADACHE; HEMATOMA; HUMAN; INFECTION; LACRIMAL GLAND DISEASE; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MENSTRUATION DISORDER; MULTICENTER STUDY; NAUSEA; NEUTROPENIA; PNEUMONIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEPSIS; STOMATITIS; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; THROMBOSIS; TREATMENT FAILURE; VOMITING;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLOOD COMPONENT TRANSFUSION; BLOOD PLATELETS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; LEUKOCYTE COUNT; MALE; MIDDLE AGED; NEUTROPHILS; PLACEBOS; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; THROMBOPOIETIN; THROMBOSIS;

EID: 0345688614     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00277-003-0737-7     Document Type: Article

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