메뉴 건너뛰기




Volumn 182, Issue 1, 2013, Pages 206-216

MiR-150 down-regulation contributes to the constitutive type i collagen overexpression in scleroderma dermal fibroblasts via the induction of integrin β3

Author keywords

[No Author keywords available]

Indexed keywords

BETA3 INTEGRIN; COLLAGEN TYPE 1; DNA; MICRORNA; MICRORNA 150; SMAD3 PROTEIN; UNCLASSIFIED DRUG;

EID: 84871347177     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.09.023     Document Type: Article
Times cited : (118)

References (61)
  • 1
    • 0024887547 scopus 로고
    • Immunologic aspects of scleroderma
    • J.H. Korn Immunologic aspects of scleroderma Curr Opin Rheumatol 1 1989 479 484 (Pubitemid 20125933)
    • (1989) Current Opinion in Rheumatology , vol.1 , Issue.4 , pp. 479-484
    • Korn, J.H.1
  • 2
    • 0025210095 scopus 로고
    • Fibroblast-matrix interactions and their role in the pathogenesis of fibrosis
    • C. Mauch, and T. Kreig Fibroblast-matrix interactions and their role in the pathogenesis of fibrosis Rheum Dis Clin North Am 16 1990 93 107 (Pubitemid 20116147)
    • (1990) Rheumatic Disease Clinics of North America , vol.16 , Issue.1 , pp. 93-107
    • Mauch, C.1    Krieg, T.2
  • 3
    • 0026955930 scopus 로고
    • Altered regulation of collagen metabolism in scleroderma fibroblasts grown within three-dimensional collagen gels
    • C. Mauch, E. Kozlowska, B. Eckes, and T. Krieg Altered regulation of collagen metabolism in scleroderma fibroblasts grown within three-dimensional collagen gels Exp Dermatol 1 1992 185 190
    • (1992) Exp Dermatol , vol.1 , pp. 185-190
    • Mauch, C.1    Kozlowska, E.2    Eckes, B.3    Krieg, T.4
  • 4
    • 0029765057 scopus 로고    scopus 로고
    • Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts: Increased proportion of high collagen-producing cells in systemic sclerosis fibroblasts
    • A. Jelaska, M. Arakawa, G. Broketa, and J.H. Korn Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts. Increased proportion of high collagen-producing cells in systemic sclerosis fibroblasts Arthritis Rheum 39 1996 1338 1346 (Pubitemid 26270093)
    • (1996) Arthritis and Rheumatism , vol.39 , Issue.8 , pp. 1338-1346
    • Jelaska, A.1    Arakawa, M.2    Broketa, G.3    Korn, J.H.4
  • 5
    • 0025222517 scopus 로고
    • The transforming growth factor-beta family
    • J. Massagué The transforming growth factor-beta family Annu Rev Cell Biol 6 1990 597 641
    • (1990) Annu Rev Cell Biol , vol.6 , pp. 597-641
    • Massagué, J.1
  • 6
    • 0024323330 scopus 로고
    • A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor β the answer?
    • E.C. LeRoy, E.A. Smith, M.B. Kahaleh, M. Trojanowska, and R.M. Silver A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor beta the answer? Arthritis Rheum 32 1989 817 825 (Pubitemid 19181003)
    • (1989) Arthritis and Rheumatism , vol.32 , Issue.7 , pp. 817-825
    • LeRoy, E.C.1    Smith, E.A.2    Kahaleh, M.B.3    Trojanowska, M.4    Silver, R.M.5
  • 7
    • 0016302998 scopus 로고
    • Increased collagen synthesis by scleroderma skin fibroblasts in vitro: A possible defect in the regulation or activation of the scleroderma fibroblast
    • E.C. LeRoy Increased collagen synthesis by scleroderma skin fibroblasts in vitro: a possible defect in the regulation or activation of the scleroderma fibroblast J Clin Invest 54 1974 880 889
    • (1974) J Clin Invest , vol.54 , pp. 880-889
    • Leroy, E.C.1
  • 8
    • 0022493764 scopus 로고
    • Co-ordinate increase in the expression of Type I and Type III collagen genes in progressive systemic sclerosis fibroblasts
    • S.A. Jimenez, G. Feldman, R.I. Bashey, R. Bienkowski, and J. Rosenbloom Co-ordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis fibroblasts Biochem J 237 1986 837 843 (Pubitemid 16003787)
    • (1986) Biochemical Journal , vol.237 , Issue.3 , pp. 837-843
    • Jimenez, S.A.1    Feldman, G.2    Bashey, R.I.3
  • 9
    • 0026666859 scopus 로고
    • Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts: Insensitivity to TGF beta 1 stimulation
    • K. Kikuchi, C.W. Hartl, E.A. Smith, E.C. LeRoy, and M. Trojanowska Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts: insensitivity to TGF beta 1 stimulation Biochem Biophys Res Commun 187 1992 45 50
    • (1992) Biochem Biophys Res Commun , vol.187 , pp. 45-50
    • Kikuchi, K.1    Hartl, C.W.2    Smith, E.A.3    Leroy, E.C.4    Trojanowska, M.5
  • 10
    • 85047692249 scopus 로고    scopus 로고
    • Impaired Smad7-Smurf-mediated negative regulation of TGF-β signaling in scleroderma fibroblasts
    • DOI 10.1172/JCI200416269
    • Y. Asano, H. Ihn, K. Yamane, M. Kubo, and K. Tamaki Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts J Clin Invest 113 2004 253 264 (Pubitemid 38544210)
    • (2004) Journal of Clinical Investigation , vol.113 , Issue.2 , pp. 253-264
    • Asano, Y.1    Ihn, H.2    Yamane, K.3    Kubo, M.4    Tamaki, K.5
  • 11
    • 0035089825 scopus 로고    scopus 로고
    • Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: Association with increased expression of transforming growth factor beta receptors
    • H. Ihn, K. Yamane, M. Kubo, and K. Tamaki Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptors Arthritis Rheum 44 2001 474 480
    • (2001) Arthritis Rheum , vol.44 , pp. 474-480
    • Ihn, H.1    Yamane, K.2    Kubo, M.3    Tamaki, K.4
  • 12
    • 0025215307 scopus 로고
    • Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin
    • R.M. Lyons, L.E. Gentry, A.F. Purchio, and H.L. Moses Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin J Cell Biol 110 1990 1361 1367
    • (1990) J Cell Biol , vol.110 , pp. 1361-1367
    • Lyons, R.M.1    Gentry, L.E.2    Purchio, A.F.3    Moses, H.L.4
  • 13
    • 0036448477 scopus 로고    scopus 로고
    • The role of TGF-β signaling in the pathogenesis of fibrosis in scleroderma
    • H. Ihn The role of TGF-beta signaling in the pathogenesis of fibrosis in scleroderma Arch Immunol Ther Exp (Warsz) 50 2002 325 331 (Pubitemid 35434568)
    • (2002) Archivum Immunologiae et Therapiae Experimentalis , vol.50 , Issue.5 , pp. 325-331
    • Ihn, H.1
  • 14
    • 33144458448 scopus 로고    scopus 로고
    • Increased expression of integrin αvβ5 induces the myofibroblastic differentiation of dermal fibroblasts
    • DOI 10.2353/ajpath.2006.041306
    • Y. Asano, H. Ihn, K. Yamane, M. Jinnin, and K. Tamaki Increased expression of integrin alphavbeta5 induces the myofibroblastic differentiation of dermal fibroblasts Am J Pathol 168 2006 499 510 (Pubitemid 43271148)
    • (2006) American Journal of Pathology , vol.168 , Issue.2 , pp. 499-510
    • Asano, Y.1    Ihn, H.2    Yamane, K.3    Jinnin, M.4    Tamaki, K.5
  • 15
    • 0027305971 scopus 로고
    • Thrombospondin causes activation of latent transforming growth factor-β secreted by endothelial cells by a novel mechanism
    • S. Schultz-Cherry, and J.E. Murphy-Ullrich Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism [Erratum appeared in J Cell Biol 1993, 122:following 1143] J Cell Biol 122 1993 923 932 (Pubitemid 23241101)
    • (1993) Journal of Cell Biology , vol.122 , Issue.4 , pp. 923-932
    • Schultz-Cherry, S.1    Murphy-Ullrich, J.E.2
  • 16
    • 33746141265 scopus 로고    scopus 로고
    • Involvement of αvβ5 integrin in the establishment of autocrine TGF-β signaling in dermal fibroblasts derived from localized scleroderma
    • DOI 10.1038/sj.jid.5700331, PII 5700331
    • Y. Asano, H. Ihn, M. Jinnin, Y. Mimura, and K. Tamaki Involvement of alphavbeta5 integrin in the establishment of autocrine TGF-beta signaling in dermal fibroblasts derived from localized scleroderma J Invest Dermatol 126 2006 1761 1769 (Pubitemid 44086510)
    • (2006) Journal of Investigative Dermatology , vol.126 , Issue.8 , pp. 1761-1769
    • Asano, Y.1    Ihn, H.2    Jinnin, M.3    Mimura, Y.4    Tamaki, K.5
  • 17
    • 25444501226 scopus 로고    scopus 로고
    • Involvement of αvβ5 integrin-mediated activation of latent transforming growth factor β1 in autocrine transforming growth factor β signaling in systemic sclerosis fibroblasts
    • DOI 10.1002/art.21246
    • Y. Asano, H. Ihn, K. Yamane, M. Jinnin, Y. Mimura, and K. Tamaki Involvement of alphavbeta5 integrin-mediated activation of latent transforming growth factor beta1 in autocrine transforming growth factor beta signaling in systemic sclerosis fibroblasts Arthritis Rheum 52 2005 2897 2905 (Pubitemid 41369121)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.9 , pp. 2897-2905
    • Asano, Y.1    Ihn, H.2    Yamane, K.3    Jinnin, M.4    Mimura, Y.5    Tamaki, K.6
  • 18
    • 28244449083 scopus 로고    scopus 로고
    • 3 contributes to the establishment of autocrine TGF-β signaling in scleroderma fibroblasts
    • Y. Asano, H. Ihn, K. Yamane, M. Jinnin, Y. Mimura, and K. Tamaki Increased expression of integrin alpha(v)beta3 contributes to the establishment of autocrine TGF-beta signaling in scleroderma fibroblasts J Immunol 175 2005 7708 7718 (Pubitemid 41713471)
    • (2005) Journal of Immunology , vol.175 , Issue.11 , pp. 7708-7718
    • Asano, Y.1    Ihn, H.2    Yamane, K.3    Jinnin, M.4    Mimura, Y.5    Tamaki, K.6
  • 19
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 20
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the Microprocessor complex
    • DOI 10.1038/nature03049
    • A.M. Denli, B.B. Tops, R.H. Plasterk, R.F. Ketting, and G.J. Hannon Processing of primary microRNAs by the Microprocessor complex Nature 432 2004 231 235 (Pubitemid 39545854)
    • (2004) Nature , vol.432 , Issue.7014 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.J.2    Plasterk, R.H.A.3    Ketting, R.F.4    Hannon, G.J.5
  • 22
    • 37549068984 scopus 로고    scopus 로고
    • Targeting microRNA expression to regulate angiogenesis
    • A. Kuehbacher, C. Urbich, and S. Dimmeler Targeting microRNA expression to regulate angiogenesis Trends Pharmacol Sci 29 2008 12 15
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 12-15
    • Kuehbacher, A.1    Urbich, C.2    Dimmeler, S.3
  • 24
    • 75749145045 scopus 로고    scopus 로고
    • MicroRNAs of the immune system: Roles in inflammation and cancer
    • J. Davidson-Moncada, F.N. Papavasiliou, and W. Tam MicroRNAs of the immune system: roles in inflammation and cancer Ann N Y Acad Sci 1183 2010 183 194
    • (2010) Ann N y Acad Sci , vol.1183 , pp. 183-194
    • Davidson-Moncada, J.1    Papavasiliou, F.N.2    Tam, W.3
  • 25
    • 0030870170 scopus 로고    scopus 로고
    • Oncostatin M stimulates transcription of the human α2(I) collagen gene via the Sp1/Sp3-binding site
    • DOI 10.1074/jbc.272.39.24666
    • H. Ihn, E.C. LeRoy, and M. Trojanowska Oncostatin M stimulates transcription of the human alpha2(I) collagen gene via the Sp1/Sp3-binding site J Biol Chem 272 1997 24666 24672 (Pubitemid 27418684)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.39 , pp. 24666-24672
    • Ihn, H.1    LeRoy, E.C.2    Trojanowska, M.3
  • 30
    • 37349059288 scopus 로고    scopus 로고
    • In situ detection of precursor and mature microRNAs in paraffin embedded, formalin fixed tissues and cell preparations
    • DOI 10.1016/j.ymeth.2007.10.008, PII S1046202307002046, MicroRNAs: Part B
    • G.J. Nuovo In situ detection of precursor and mature microRNAs in paraffin embedded, formalin fixed tissues and cell preparations Methods 44 2008 39 46 (Pubitemid 350297988)
    • (2008) Methods , vol.44 , Issue.1 , pp. 39-46
    • Nuovo, G.J.1
  • 31
    • 78650779471 scopus 로고    scopus 로고
    • Down-regulation of mir-424 contributes to the abnormal angiogenesis via MEK1 and cyclin E1 in senile hemangioma: Its implications to therapy
    • T. Nakashima, M. Jinnin, T. Etoh, S. Fukushima, S. Masuguchi, K. Maruo, Y. Inoue, T. Ishihara, and H. Ihn Down-regulation of mir-424 contributes to the abnormal angiogenesis via MEK1 and cyclin E1 in senile hemangioma: its implications to therapy PLoS One 5 2010 e14334
    • (2010) PLoS One , vol.5 , pp. 14334
    • Nakashima, T.1    Jinnin, M.2    Etoh, T.3    Fukushima, S.4    Masuguchi, S.5    Maruo, K.6    Inoue, Y.7    Ishihara, T.8    Ihn, H.9
  • 33
    • 77649205818 scopus 로고    scopus 로고
    • Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR)
    • [Erratum appeared in Methods 2010, 52:268]
    • E.M. Kroh, R.K. Parkin, P.S. Mitchell, and M. Tewari Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR) [Erratum appeared in Methods 2010, 52:268] Methods 50 2010 298 301
    • (2010) Methods , vol.50 , pp. 298-301
    • Kroh, E.M.1    Parkin, R.K.2    Mitchell, P.S.3    Tewari, M.4
  • 34
    • 0347755643 scopus 로고    scopus 로고
    • The microRNA Registry
    • S. Griffiths-Jones The microRNA Registry Nucleic Acids Res 32 Database issue 2004 D109 D111
    • (2004) Nucleic Acids Res , vol.32 , Issue.DATABASE ISSUE
    • Griffiths-Jones, S.1
  • 37
    • 78651293534 scopus 로고    scopus 로고
    • MiRBase: Integrating microRNA annotation and deep-sequencing data
    • A. Kozomara, and S. Griffiths-Jones miRBase: integrating microRNA annotation and deep-sequencing data Nucleic Acids Res 39 Database issue 2011 D152 D157
    • (2011) Nucleic Acids Res , vol.39 , Issue.DATABASE ISSUE
    • Kozomara, A.1    Griffiths-Jones, S.2
  • 38
    • 12944327831 scopus 로고    scopus 로고
    • Cell type-specific regulation of the TGF-β-responsive α2(I) collagen gene by CpG methylation
    • DOI 10.1002/jcp.20205
    • K. Yamane, H. Suzuki, H. Ihn, M. Kato, H. Yoshikawa, and K. Tamaki Cell type-specific regulation of the TGF-beta-responsive alpha2(I) collagen gene by CpG methylation J Cell Physiol 202 2005 822 830 (Pubitemid 40175858)
    • (2005) Journal of Cellular Physiology , vol.202 , Issue.3 , pp. 822-830
    • Yamane, K.1    Suzuki, H.2    Ihn, H.3    Kato, M.4    Yoshikawa, H.5    Tamaki, K.6
  • 39
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
    • B.P. Lewis, C.B. Burge, and D.P. Bartel Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Cell 120 2005 15 20 (Pubitemid 40094598)
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 40
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • R.C. Friedman, K.K. Farh, C.B. Burge, and D.P. Bartel Most mammalian mRNAs are conserved targets of microRNAs Genome Res 19 2009 92 105
    • (2009) Genome Res , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 41
    • 34250805982 scopus 로고    scopus 로고
    • MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing
    • DOI 10.1016/j.molcel.2007.06.017, PII S1097276507004078
    • A. Grimson, K.K. Farh, W.K. Johnston, P. Garrett-Engele, L.P. Lim, and D.P. Bartel MicroRNA targeting specificity in mammals: determinants beyond seed pairing Mol Cell 27 2007 91 105 (Pubitemid 46991392)
    • (2007) Molecular Cell , vol.27 , Issue.1 , pp. 91-105
    • Grimson, A.1    Farh, K.K.-H.2    Johnston, W.K.3    Garrett-Engele, P.4    Lim, L.P.5    Bartel, D.P.6
  • 42
    • 80455154984 scopus 로고    scopus 로고
    • Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs
    • D.M. Garcia, D. Baek, C. Shin, G.W. Bell, A. Grimson, and D.P. Bartel Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs Nat Struct Mol Biol 18 2011 1139 1146
    • (2011) Nat Struct Mol Biol , vol.18 , pp. 1139-1146
    • Garcia, D.M.1    Baek, D.2    Shin, C.3    Bell, G.W.4    Grimson, A.5    Bartel, D.P.6
  • 43
    • 77955963884 scopus 로고    scopus 로고
    • Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites
    • D. Betel, A. Koppal, P. Agius, C. Sander, and C. Leslie Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites Genome Biol 11 2010 R90
    • (2010) Genome Biol , vol.11 , pp. 90
    • Betel, D.1    Koppal, A.2    Agius, P.3    Sander, C.4    Leslie, C.5
  • 44
  • 49
    • 38849145861 scopus 로고    scopus 로고
    • Prediction of both conserved and nonconserved microRNA targets in animals
    • DOI 10.1093/bioinformatics/btm595
    • X. Wang, and I.M. El Naqa Prediction of both conserved and nonconserved microRNA targets in animals Bioinformatics 24 2008 325 332 (Pubitemid 351189007)
    • (2008) Bioinformatics , vol.24 , Issue.3 , pp. 325-332
    • Wang, X.1    El Naqa, I.M.2
  • 50
    • 44149083586 scopus 로고    scopus 로고
    • MiRDB: A microRNA target prediction and functional annotation database with a wiki interface
    • DOI 10.1261/rna.965408
    • X. Wang miRDB: a microRNA target prediction and functional annotation database with a wiki interface RNA 14 2008 1012 1017 (Pubitemid 351717482)
    • (2008) RNA , vol.14 , Issue.6 , pp. 1012-1017
    • Wang, X.1
  • 51
    • 79151483332 scopus 로고    scopus 로고
    • MicroRNA-101 downregulates Alzheimer's amyloid-beta precursor protein levels in human cell cultures and is differentially expressed
    • J.M. Long, and D.K. Lahiri MicroRNA-101 downregulates Alzheimer's amyloid-beta precursor protein levels in human cell cultures and is differentially expressed Biochem Biophys Res Commun 404 2011 889 895
    • (2011) Biochem Biophys Res Commun , vol.404 , pp. 889-895
    • Long, J.M.1    Lahiri, D.K.2
  • 57
    • 34248216649 scopus 로고    scopus 로고
    • Tumor-released microvesicles as vehicles of immunosuppression
    • DOI 10.1158/0008-5472.CAN-07-0520
    • R. Valenti, V. Huber, M. Iero, P. Filipazzi, G. Parmiani, and L. Rivoltini Tumor-released microvesicles as vehicles of immunosuppression Cancer Res 67 2007 2912 2915 (Pubitemid 46724823)
    • (2007) Cancer Research , vol.67 , Issue.7 , pp. 2912-2915
    • Valenti, R.1    Huber, V.2    Iero, M.3    Filipazzi, P.4    Parmiani, G.5    Rivoltini, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.