JmjC-domain containing histone demethylase 1B-mediated p15Ink4b suppression promotes the proliferation of leukemic progenitor cells through modulation of cell cycle progression in acute myeloid leukemia

Molecular Carcinogenesis

Volumn 52, Issue 1, 2013, Pages 57-69

  Nakamura, Satoki ^a   Tan, Lin ^a   Nagata, Yasuyuki ^a   Takemura, Tomonari ^a   Asahina, Aya ^a   Yokota, Daisuke ^a   Yagyu, Tomohiro ^a   Shibata, Kiyoshi ^a   Fujisawa, Shinya ^b   Ohnishi, Kazunori ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HAMAMATSU MEDICAL CENTER   (Japan)

Author keywords

ALDHhi CD34+ cells; AML; Cell cycle; JHDM1B; P15Ink4b

Indexed keywords

ALDEHYDE DEHYDROGENASE; CD34 ANTIGEN; CYCLIN DEPENDENT KINASE INHIBITOR 2B; HISTONE DEMETHYLASE; HISTONE DEMETHYLASE 1B; HISTONE H3; MESSENGER RNA; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ARTICLE; CANCER STEM CELL; CELL CYCLE PROGRESSION; CELL POPULATION; CELL PROLIFERATION; CELL VIABILITY; COLONY FORMATION; CONTROLLED STUDY; DEMETHYLATION; ENZYME ACTIVITY; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ADULT; AGED; ALDEHYDE DEHYDROGENASE; ANTIGENS, CD34; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P15; F-BOX PROTEINS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MIDDLE AGED; NEOPLASTIC STEM CELLS; OXIDOREDUCTASES, N-DEMETHYLATING; PROTEIN KINASE INHIBITORS;

EID: 84871327693     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20878     Document Type: Article

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