Chemopreventive property of Trichosanthes dioica root against 3-methylcholanthrene-induced carcinogenesis in albino mice

Journal of Environmental Pathology, Toxicology and Oncology

Volumn 31, Issue 2, 2012, Pages 109-119

  Bhattacharya, Sanjib ^a   Haldar, Pallab Kanti ^b  

^a Bengal School of Technology   (India)

^b JADAVPUR UNIVERSITY   (India)

Author keywords

3 methylcholanthrene; Antioxidant; Carcinogenesis; Chemoprevention; Trichosanthes dioica

Indexed keywords

3 METHYLCHOLANTHRENE; ANTINEOPLASTIC AGENT; CATALASE; FLUOROURACIL; GLUTATHIONE; GLUTATHIONE TRANSFERASE; PLANT EXTRACT; SUPEROXIDE DISMUTASE; TRICHOSANTHES DIOICA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER SURVIVAL; CARCINOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROSARCOMA; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; TRICHOSANTHES; TRICHOSANTHES DIOICA;

ANIMALS; CATALASE; CHEMOPREVENTION; DISEASE MODELS, ANIMAL; FIBROSARCOMA; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LIPID PEROXIDATION; LIVER NEOPLASMS; MALE; METHYLCHOLANTHRENE; MICE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; SUPEROXIDE DISMUTASE; TREATMENT OUTCOME; TRICHOSANTHES;

MUS; TRICHOSANTHES DIOICA;

EID: 84871325235     PISSN: 07318898     EISSN: None     Source Type: Journal    
DOI: 10.1615/JEnvironPatholToxicolOncol.v31.i2.30     Document Type: Article

References (69)

1. Nitha B, Meera CR, Janardhanan KK. Antitumor activity of ethanolic extract of Lentinus dicholamellatus. Amala Res Bull. 2005;25:165-168.
2. Greenwald P, Kellof GJ. The role of chemoprevention in cancer control. IARC Sci Publ. 1996;139:13-22.
3. Mascarenhas M. Structure-activity characterization, a quick method to screen mushrooms for the presence of antitumor glucans. Mushroom Res. 1994;3:77-80.
4. Maroni A, editor. Polynuclear aromatic hydrocarbons. In: Indoor air quality. A comprehensive reference book. Air quality monographs. Vol. 3. Amsterdam: Elsevier; 1995. p. 79-84.
5. Zur Hausen H. Virus in human cancer. Science. 1991;254:1167-1173.
6. Kim CM, Koike K, Saito I, Miyamura T, Jay G. HBx gene of hepatitis B virus indicates liver cancer in transgenic mice. Nature. 1991;351:317-320.
7. Levin W, Buening MK, Wood AW, Chang RL, Thakker DR, Jerina DM, Conney AH. Tumorigenic activity of 3-methylcholanthrene metabolites on mouse skin and in newborn mice. Cancer Res. 1979;39:3549-3553.
8. Polynuclear aromatic hydrocarbons (PAH). In: Air quality guidelines for Europe. Copenhagen: World Health Organization Regional Office for Europe; 1987. p. 105-117.
9. Menzie CA, Potocki BB, Santodonato J. Exposure to carcinogenic PAHs in the environment. Environ Sci Technol. 1992;26:1278-1284.
10. Kirtikar KR, Basu BD. Indian medicinal plants. New Delhi: Bishen Singh Mahendra Pal Singh; 1935.
11. The wealth of India: raw materials: New Delhi: Publication and Information Directorate, CSIR; 1976.
12. Nadkarni KM. Indian materia medica. Bombay: Popular Prakashan; 1976.
13. Sharma PC, Yelne MB, Dennis TJ. Database on medicinal plants used in Ayurveda. New Delhi: Central Council for Research in Ayurveda and Siddha; 2002.
14. Sharma G, Pant MC. Preliminary observations on serum biochemical parameters of albino rabbits fed on seeds of Trichosanthes dioica (Roxb). Indian J Med Res. 1988;87:398-400.
15. Sharma G, Pant MC. Effect of raw deseeded fruit powder of Trichosanthes dioica (Roxb) on blood sugar, serum cholesterol, high density lipoprotein, phospholipid and triglyceride levels in the normal albino rabbits. Indian J Physiol Pharmacol. 1988;32:161-163.
16. Sharma G, Pant MC. Effect of feeding Trichosanthes dioica (Parval) whole fruits on blood glucose, serum triglycerides, phospholipid, cholesterol and high density lipoprotein-cholesterol levels in the normal albino rabbits. Curr Sci. 1988;57:1085-1087.
17. Sharma G, Pandey DN, Pant MC. Biochemical evaluation of feeding Trichosanthes dioica seeds in normal and mild diabetic human subjects in relation to lipid profile. Indian J Physiol Pharmacol. 1990;34:146-148.
18. Kabir S. The novel peptide composition of the seeds of Trichosanthes dioica Roxb. Cytobios. 2000;103:121-131.
19. Sultan NA, Kenoth R, Swamy MJ. Purification, physicochemical characterization, saccharide specificity, and chemical modification of a Gal/GalNAc specific lectin from the seeds of Trichosanthes dioica. Arch Biochem Biophys. 2004;432:212-221.
20. Sultan NA, Swamy MJ. Fluorescence quenching and time-resolved fluorescence studies on Trichosanthes dioica seed lectin. J Photochem Photobiol. 2005;80:93-100.
21. Sharmila BG, Kumar G, Rajasekara PM. Cholesterol lowering activity of the aqueous fruit extract of Trichosanthes dioica Roxb. in normal and streptozotocin diabetic rats. J Clin Diagnostic Res. 2007;1:561-569.
22. Ghaisas MM, Tanwar MB, Ninave PB, Navghare VV, Takawale AR, Zope VS, Deshpande AD. Hepatoprotective activity of aqueous and ethanolic extract of Trichosanthes dioica Roxb. in ferrous sulphate-induced liver injury. Pharmacologyonline. 2008;4:127-135.
23. Rai PK, Jaiswal D, Rai DK, Sharma B, Watal G. Effect of water extract of Trichosanthes dioica fruits in streptozotocin induced diabetic rats. Indian J Clin Biochem. 2008;23:387-390.
24. Rai PK, Jaiswal D, Diwakar S, Watal G. Antihyperglycemic profile of Trichosanthes dioica seeds in experimental models. Pharm Biol. 2008;46:360-365.
25. Bhattacharya S, Haldar PK, Ghosh AK. In vitro effects of Trichosanthes dioica leaves on annelids and nematodes. Pharmacologyonline. 2009;5:242-248.
26. Bhattacharya S, Haldar PK, Ghosh AK. Paralytic and lethal effects of Trichosanthes dioica root extracts in experimental worms. Pharm Biol. 2010;48:960-965.
27. Bhattacharya S, Haldar PK. Antibacterial activity of Trichosanthes dioica root. Global J Pharmacol 2010;4:122-126.
28. Bhattacharya S, Haldar PK. Evaluation of in vitro cytotoxic effect of Trichosanthes dioica root. Pharmacognosy Res. 2010;2:355-358.
29. Bhattacharya S, Prasanna A, Haldar PK. Evaluation of antiproliferative activity of Trichosanthes dioica root against Ehrlich ascites carcinoma cells. Acad J Cancer Res. 2011;4:38-42.
30. Bhattacharya S, Prasanna A, Majumdar P, Kumar RBS, Haldar PK. Antitumor efficacy and amelioration of oxidative stress by Trichosanthes dioica root against Ehrlich ascites carcinoma in mice. Pharm Biol. 2011;49:927-935.
31. Bhattacharya S, Haldar PK. Evaluation of antimitotic and genotoxic effects of the triterpenoid enriched extract from Trichosanthes dioica root. Am Euras J Toxicol Sci. 2012;4:20-23.
32. Bhattacharya S, Haldar PK. The triterpenoid fraction from Trichosanthes dioica root exhibits antiproliferative activity against Ehrlich ascites carcinoma in albino mice: Involvement of possible antioxidant role. J Exp Ther Oncol. 2012;9:281- 290.
33. Bhattacharya S, Haldar PK. Ameliorative effect Trichosanthes dioica root against experimentally induced arsenic toxicity in male albino rats. Environ Toxicol Pharmacol. 2012;33:394-402.
34. Bhattacharya S, Haldar PK. Ameliorative effect of Trichosanthes dioica root against arsenic-induced brain toxicity in albino rats. Toxicol Environ Chem. 2012;94:769-778.
35. Harborne JB. Phytochemical methods: a guide to modern techniques of plant analysis. 3rd edition. New Delhi: Springer (India) Pvt. Ltd.; 1998.
36. Wagner H, Bladt B. Plant drug analysis, a thin layer chromatography atlas. Berlin, Hiedelberg: Springer Verlag; 1996.
37. D'Armour FE, Blood FR, Belden DA. The manual for laboratory works in mammalian physiology. 3rd edition. Illinois, Chicago: The University of Chicago Press; 1965.
38. Wintrobe MM, Lee GR, Boggs DR, Bithel TC, Athens JW, Foerster J. Clinical hematology. 5th edition. Philadelphia: Lea and Febiger; 1961.
39. Dacie JV, Lewis SM. Practical hematology. 2nd edition. London: J and A Churchill Ltd.; 1958.
40. Ohkawa H, Onishi N, Yagi K. Assay for lipid peroxidation in animal tissue by thiobarbituric acid reaction. Anal Biochem. 1979;95:351-358.
41. Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959;82:70-77.
42. Habig WH, Pabst MJ, Jakoby WB. Glutathione-Stransferase: the first enzymatic step in mercapturic acid formation. J Biol Chem. 1974;249:7130-7139.
43. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
44. Kakkar P, Das B, Vishwanath PN. A modified spectrophotometric assay of superoxide dismutase. Indian J Biochem Biophys. 1984;21:130-132.
45. Sinha KA. Colorimetric assay of catalase. Anal Biochem. 1972;47:389-394.
46. Surh YJ. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer. 2003;3:768-780.
47. Price VE, Greenfield RE. Anemia in cancer. In: Grenstein JP, Haddaw A, editors. Advances in cancer research. Vol. V. New York: Academic Press; 1958. p. 199-200.
48. Hogland HC. Hematological complications of cancer chemotherapy. Semin Oncol. 1982;9:95-102.
49. Gupta M, Mazumder UK, Kumar RS, Kumar TS. Antitumor activity and antioxidant role of Bauhinia racemosa against Ehrlich ascites carcinoma in Swiss albino mice. Acta Pharmacol Sin. 2004;25:1070-1076.
50. Haldar PK, Bhattacharya S, Dewanjee S, Mazumder UK. Chemopreventive efficacy of Wedelia calendulaceae against 20-methylcholanthreneinduced carcinogenesis in mice. Environ Toxicol Pharmacol. 2011;31:10-17.
51. Pahl H, Baeuerle P. Oxygen and the control of gene expression. Bioessays. 1994;16:497 -502.
52. Oberley TD. Oxidative damage and cancer. Am J Pathol. 2002;160:403-408.
53. Balasubramaniyan N, Subramanian S, Govindasamy S. Status of antioxidant systems in human carcinoma of uterine cervix. Cancer Lett. 1994;87:187-192.
54. Casado A, Torre R, Lopez-Fernandez M, Carrascosa D, Casado M, Ramirez M. Superoxide dismutase and catalase blood levels in patients with malignant diseases. Cancer Lett. 1995;93:187-192.
55. Yellin S, Davidson B, Pinto J, Sacks P, Qiao C, Schantz S. Relationship of glutathione and glutathione-S-transferase to cisplatin sensitivity in human head and neck squamous carcinoma cell lines. Cancer Lett. 1994;85:223-232.
56. Sharma R, Singhal S, Srivastava S, Bajpai K, Frankel E, Awasthi S. Glutathione and glutathione linked enzymes in human small lung cancer cell lines. Cancer Lett. 1993;75:111-119.
57. Kuttan G, Menon LG, Kuttan R. Prevention of 20-methylcholanthrene-induced sarcoma by a mistletoe extract, Iscador. Carcinogenesis. 1996;17:1107-1109.
58. Yoshikawa T, Tanaka H, Yoshida H, Sato O, Sugino N, Kondo M. Adjuvant arthritis and lipid peroxidation protection protection by superoxide dismutase. Lipid Peroxide Res. 1983;7:108-112.
59. Niki E, Yamamoto Y, Komuru E, Sato K. Membrane damage due to lipid oxidation. Am J Clin Nutr. 1991;53:201S-205S.
60. Wiseman H, Halliwell B. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem J. 1996;313:17-29.
61. Neilson F, Mikkelson BB, Nielsen JB, Andersen HR, Grandjean P. Plasma malondialdehyde as biomarker for oxidative stress, reference interval and effects of life-style factors. Clin Chemist. 1997;47:1209-1214.
62. Arias IM, Jakoby WB. Glutathione: metabolisms and functions. New York: Raven Press; 1976.
63. Gmunder H, Droge W. Differential effects of glutathione depletion on T-cell subsets. Cell Immunol. 1991;138:229-237.
64. Devi KN, Reddy CC, Raveendra A, Thyagaraju K. Effect of β-methylcholanthrene on glutathione S-transferases of rat testis. Curr Sci. 2002;82:1282-1287.
65. Mulder TPJ, Manni JJ, Roelof HMJ, Peters WHM, Wiersma A. Glutathione-S-transferase and glutathione in human head and neck cancer. Carcinogenesis. 1995;16:619-624.
66. Jiau-Jian L, Larry WO. Over expression of manganese-containing superoxide dismutase confers resistance to the cytotoxicity of tumor necrosis factor α and/or hyperthermia. Cancer Res. 1977;57:1991-1998.
67. Wall KL, Wenshi G, Koppele JM, Kwei GY, Kauffman FC, Thurman RG. The liver plays a central role in the mechanism of chemical carcinogenesis due to polycyclic aromatic hydrocarbons. Carcinogenesis. 1991;12:783-786.
68. Chen JC, Chiu MH, Nie RL, Cordell GA, Qiu SX. Cucurbitacins and cucurbitane glycosides: structures and biological activities. Nat Prod Rep. 2005;22:386-399.
69. Miro M. Cucurbitacins and their pharmacological effects. Photother Res. 2006;9:159-168.