Activation of TGF-β Pathway by Areca Nut Constituents: A Possible Cause of Oral Submucous Fibrosis

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Khan, Imran ^a   Kumar, Neeraj ^a   Pant, Ila ^a   Narra, Sivakrishna ^a   Kondaiah, Paturu ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID DERIVATIVE; ARECAIDINE; ARECOLINE; CATECHIN; GUVACINE; POLYPHENOL DERIVATIVE; SMAD2 PROTEIN; TANNIN; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1;

ARTICLE; BETEL NUT; CONTROLLED STUDY; EPITHELIUM CELL; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUTH DISEASE; NUCLEOTIDE SEQUENCE; PHYTOCHEMISTRY; PROTEIN PHOSPHORYLATION; RISK FACTOR; SIGNAL TRANSDUCTION; UNINDEXED SEQUENCE; UPREGULATION;

ARECA; ARECOLINE; BIOLOGICAL MARKERS; CELLS, CULTURED; COLLAGEN; FIBROBLASTS; GENE EXPRESSION PROFILING; GINGIVA; HUMANS; KERATINOCYTES; MASTICATION; NUTS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORAL SUBMUCOUS FIBROSIS; PHOSPHORYLATION; PLANT EXTRACTS; PLANTS, TOXIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

ARECA CATECHU;

EID: 84871318315     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051806     Document Type: Article

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