Phenotype refinement for comorbid attention deficit hyperactivity disorder and reading disability

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 162, Issue 1, 2013, Pages 44-54

  Sheikhi, Abdullah R ^a,b   Martin, Neilson ^a   Hay, David ^a   Piek, Jan P ^a  

^a CURTIN UNIVERSITY   (Australia)

^b UNIVERSITY OF BENGHAZI   (Libyan Arab Jamahiriya)

Author keywords

Genetics; Heterogeneity; Latent class analysis; Phenomics; Twins

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; ATTENTION DEFICIT DISORDER; AUSTRALIA; CHILD; CLUSTER ANALYSIS; COMORBIDITY; CONTROLLED STUDY; DISEASE SEVERITY; DSM-IV; DYSLEXIA; FEMALE; GENE CLUSTER; HUMAN; LATENT CLASS ANALYSIS; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; PSYCHOLOGIC TEST; QUESTIONNAIRE; READING DISABILITY MEASURE; SCHOOL CHILD; THE AUSTRALIAN TWIN BEHAVIOUR RATING SCALE; TWIN AND SIBLING QUESTIONNAIRE; TWINS;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; AUSTRALIA; CHI-SQUARE DISTRIBUTION; CHILD; CHILD, PRESCHOOL; COMORBIDITY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DYSLEXIA; FEMALE; HUMANS; MALE; MODELS, BIOLOGICAL; PHENOTYPE; PREVALENCE; READING; SEX CHARACTERISTICS; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 84871310490     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.32119     Document Type: Article

References (52)

1. American Psychiatric Association. 1980. Diagnostic and statistical manual of mental disorders. Washington, DC: American Psychiatric Association.
2. American Psychiatric Association. 1987. Diagnostic and statistical manual of mental disorders. Washington, DC: American Psychiatric Association.
3. American Psychiatric Association. 1994. Diagnostic and statistical manual of mental disorders. Washington, DC: American Psychiatric Association.
4. American Psychiatric Association. 2000. Diagnostic and statistical manual of mental disorders text revision. Washington, DC: American Psychiatric Association.
5. Barkley R. 1997. ADHD and the nature of self-control. New York: Guilford Press.
6. Bennett KA, Hay DA, Piek J, Pearsall-Jones J, Levy F, Martin N. 2006. The Australian Twin ADHD Project: Current status and future directions. Twin Res Hum Genet 9: 718-726.
7. Biederman J, Faraone S. 2005. Attention deficit hyperactivity disorder. Lancet 366(9481): 237-248.
8. Bilder R. 2008. Phenomics: Building scaffolds for biological hypotheses in the post-genomic era. Biol Psychiatry 63: 439-440.
9. Bilder R, Sabb F, Cannon T, London E, Jentsch J, Parker D, Poldrack R, Evans C, Freimer N. 2009. Phenomics: The systematyic study of phenotypes on a genome-wide scale. Neuroscince 146(1): 30-42.
10. Cheung CH, Wood AC, Paloyelis Y, Arias-Vasquez A, Buitelaar JK, Franke B, Miranda A, Mulas F, Rommelse N, Sergeant JA, et al. 2012. Aetiology for the covariation between combined.type ADHD and reading difficulties in a family study: The role of IQ. JChild Psychol Psychiatry DOI: 10.1111/j.1469-7610.2012.02527.x
11. Cohen D, Dibble E, Grawe J, Pollin W. 1975. Reliably separating identical from fraternal twins. Arch Gen Psychiatry 32: 1371-1375.
12. Cohen P, Cohen J, Kasen S, Velez C, Hartmark C, Johnson J, Rojas M, Brook J, Streuning EL. 1993. An epidemiological study of disorders in late childhood and adolescence-I. Age- and gender-specific prevalence. J Child Psychol Psychiatry 34: 851-867.
13. Dempster A, Laird N, Rubin D. 1977. Maximum likelihood from incomplete data via the EM algorithm. J R Stat Soc Ser B 39: 1-38.
14. Georgiades S, Szatmari P, Zwaigenbaum L, Duku E, Bryson S, Roberts W, Goldberg J, Mahoney W. 2007. Structure of the Autism symptom phenotype: A proposed multidimensional model. Am Acad Child Adolesc Psychiatry 46(2): 188-196.
15. Hay DA, Levy F. 2004. Twin and Sibling Questionnaire. Unpublished Questionnaire, Curtin University of Technology, Perth, WA.
16. Hay DA, McStephen M, Levy F. 2001. Introduction to the genetic analysis of attentional disorders. In: Levy F, Hay DA, editors. Attention, genes and ADHD. Philadelphia: Brunner-Routledge. pp 7-34.
17. Hay DA, McStephen M, Levy F, Pearsall-Jones J. 2002. Recruitment and attrition in twin registrar studies of childhood behavior: The example of the Australian Twin ADHD Project. Twin Res 5(5): 324-328.
18. Heath AC, Nyholt DR, Neuman R, Madden P, Bucholz K, Todd R. 2003. Zygosity diagnosis in the absence of genotypic data: An approach using latent class analysis. Twin Res 6(1): 22-26.
19. Hudziak JJ, Heath AC, Madden PAF, Reich W, Bucholz KK, Slutske WS, Bierut LJ, Neuman RJ, Todd RD. 1998. Latent class and factor analysis of DSM-IV ADHD: A twin study of female adolescents. J Am Acad Child AdolescPsychiatry 37: 848-857.
20. Khan S, Faraone S. 2006. The genetics of ADHD: A literature review of 2005. Curr Psychiatry Rep 8: 393-397.
21. Levy F, Hay DA. 2001. Attention genes and ADHD. Philadelphia: PN Brunner-Routledge. p. 263.
22. Levy F, Hay D, McStephen M, Wood C, Waldman I. 1996. Twin-sibling differences in perinatal reports of ADHD, speech, reading and behavior problems. JChild Psychol Psychiatry 37: 569-578.
23. Levy F, Hay DA, McStephen M, Wood C. 1997. Attention-deficit hyperactivity disorder: A category or a continuum? Genetic analysis of a large-scale twin study. J Am Acad Child Adolesc Psychiatry 36: 737-744.
24. Levy F, Hay D, Bennett K, McStephen M. 2005. Gender differences in ADHD subtype comorbidity J Am Acad Child Adolesc Psychiatry 44(4): 368-376.
25. McCutcheon AL. 1987. Latent class analysis. Newbury Park, CA: Sage Publications.
26. McGrath L, Smith S, Pennington B. 2006. Breakthroughs in the search for dyslexia candidate genes. Trends Mol Med 12(7): 333-341.
27. Meng H, Powers N, Tang L, Cope N, Zhang P-X, Fuleihan R, Gibson C, Page G, Gruen J. 2011. A dyslexia-associated variant in DCDC2 changes gene expression. Behav Genet 41: 58-66.
28. Neuman RJ, Todd RD, Heath AC, Reich W, Hudziak JJ, Bucholz KK, Madden PAF, Begleiter H, Porjesz B, Kuperman S, et al. 1999. Evaluation of ADHD typology in three contrasting samples: A latent class approach. J Am AcadChild Adolesc Psychiatry 38(1): 1-14.
29. Neuman R, Sitdhiraksa N, Reich W, Ji T, Joyner C, Sun L, Todd R. 2005. Estimation of prevalence of DSM-IV and latent-defined ADHD subtypes in a population-based sample of child and adolescent twins Twin Res Hum Genet 8(4): 392-401.
30. Nichols R, Bilbro W. 1966. The diagnosis of twin zygosity. Acta Genet Stat Med 16: 265-275.
31. Pennington BF. 2006. From single to multiple deficit models of developmental disorders. Cognition 101: 385-413.
32. Pennington BF. 2009. Diagnosing learning disorders: A neuropsychological framework, 2nd edition. New York, NY: The Guilford Press.
33. Rasmussen E, Todd R, Neuman R, Heath A, Reich W, Rohde L. 2002a. Comparison of male adolescent-report of attention-deficit/hyperactivity disorder (ADHD) symptoms across two cultures using latent class and principal components analysis. J Child Psychol Psychiatry 43(6): 797-805.
34. Rasmussen ER, Neuman RJ, Heath AC, Levy F, Hay D, Todd RD. 2002b. Replication of the latent class structure of Attention-Deficit/Hyperactivity Disorder (ADHD) subtypes in a sample of Australian twins. J Child Psychol Psychiatry 43(8): 1018-1028.
35. Rasmussen ER, Neuman RJ, Heath AC, Levy F, Hay D, Todd RD. 2004. Familial clustering of latent class and DSM-IV defined attention-deficit/hyperactivity disorder (ADHD) subtypes. J Child Psychol Psychiatry 45(3): 589-598.
36. Sabb F, Burggren A, Higier R, Fox J, He J, Parker D, Poldrack R, Chu W, Cannon T, Freimer N., et al. 2009. Challenges in phenotype definition in the whole-genome era: Multivariate models of memory and intelligence. Neuroscince 164: 88-107.
37. Shaywitz SE, Shaywitz BA, Fletcher J, Escobar M. 1990. Prevalence of reading disability in boys and girls. Results of the Connecticut longitudinal study. J Am Med Assoc 264: 998-1002.
38. Stefanatos G, Baron I. 2007. Attention-deficit/hyperactivity disorder: A neuropsychological perspective towards DSM-V. Neuropsychol Rev 17(1): 5-38.
39. Szatmari P, Maziade M, Zwaigenbaum L, Merette C, Roy M, Joober R, Palmour R. 2007. Informative phenotypes for genetic studies of psychiatric disorders. Am J Med Genet Part B 144B: 581-588.
40. Tishler P, Carey V. 2007. Can comparison of MZ- and DZ-twin concordance rates be used invariably to estimate heritability? Twin Res Hum Genet 10(5): 712-717.
41. Todd RD, Rasmussen ER, Neuman RJ, Reich W, Hudziak JJ, Bucholz KK, Madden PAF, Heath AC. 2001. Familiality and heritability of subtypes of attention deficit hyperactivity disorder in a population sample of adolescent female twins. Am J Psychiatry 158: 1891-1898.
42. Todd R, Sitdhiraksa N, Reich WJIT, Joyner C, Heath A, Neuman R. 2002. Discrimination of DSM-IV and latent class attention-deficit/hyperactivity disorder subtypes by educational and cognitive performance in a population-based sample of child and adolescent twins. J Am Acad Child Adolesc Psychiatry 41(7): 820-828.
43. Todd RD, Huang H, Smalley SL, Nelson SF, Willcutt EG, Pennington BF, Smith SD, Faraone SV, Neuman RJ. 2005. Collaborative analysis of DRD4 and DAT genotypes in population-defined ADHD subtypes. J Child Psychol Psychiatry 46(10): 1067-1073.
44. Todd RD, Huang H, Todorov AA, Neuman RJ, Reiersen AM, Henderson CA, Reich WC. 2008. Predictors of stability of attention-deficit/hyperactivity disorder subtypes from childhood to young adulthood. J Am Acad Child Adolesc Psychiatry 47(1): 76-85.
45. Volk H, Henderson C, Neuman R, Todd R. 2006. Validation of population-based ADHD subtypes and identification of three clinically impaired subtypes. Am J Med Genet Part B 141B: 312-318.
46. Willcutt E. 2008. In: Sheikhi A, editor. Thesis examination. Perth.
47. Willcutt E, Pennington B, DeFries J. 2000. Twin study of the etiology of comorbidity between reading disability and attention-deficit/hyperactivity disorder. Am J Med Genet Part B 96: 293-301.
48. Willcutt E, Boada R, Riddle M, Pennington B. 2003a. Internal and external validty ratings of reading difficulties. Boulder.
49. Willcutt EG, DeFries JC, Pennington BF, Olson RK, Smith SD, Cardon LR. 2003b. Genetic etiology of comorbid reading difficulties and ADHD. In: Plomin R, DeFries J, McGuffin P, Craig I, editors. Behavioral genetics in a postgenomic era. Washington DC: American Psychological Association. pp. 227-246.
50. Willcutt E, Boada R, Riddle M, Chhabildas N, De Fries J, Pennington B. 2011. Colorado learning difficulties questionnaire: Validation of a parent-report screening measure for learning difficulties. Psychol Assess 23(3): 778-791.
51. Wood AC, Buitelaar J, Rijsdiik F, Asherson P, Kuntsi J. 2010. Rethinking shared environment as a source of variance underlying attention-deficit/hyperactivity disorder symptoms: Comment on Burt (2009) Psychol Bull 136: 331-340.
52. Zumberge A, Baker L, Manis F. 2007. Focus on Words: A twin study of reading and inattention. Behav Genet 37: 284-293.