Simultaneous Non-Negative Matrix Factorization for Multiple Large Scale Gene Expression Datasets in Toxicology

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Lee, Clare M ^a   Mudaliar, Manikhandan A V ^b   Haggart, D R ^e   Wolf, C Roland ^c,d   Miele, Gino ^e   Vass, J Keith ^a   Higham, Desmond J ^a   Crowther, Daniel ^f  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d CXR Biosciences Ltd   (United Kingdom)

^e Epsistem Ltd   (United Kingdom)

^f Sanofi   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; CREATININE; LACTATE DEHYDROGENASE; NITROGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PPM 201; UNCLASSIFIED DRUG; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALGORITHM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; CREATININE BLOOD LEVEL; DIABETES MELLITUS; GENE CLUSTER; GENE EXPRESSION; GENETIC DATABASE; HEART; HISTOPATHOLOGY; KIDNEY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER; LIVER TOXICITY; MATHEMATICAL ANALYSIS; MOLECULAR EVOLUTION; MOUSE; NON NEGATIVE MATRIX FACTORIZATION; NONHUMAN; NUCLEOTIDE SEQUENCE; SKELETAL MUSCLE; TOXICITY TESTING; TOXICOLOGY; UREA NITROGEN BLOOD LEVEL;

ALGORITHMS; ANIMALS; CLUSTER ANALYSIS; DATABASES, FACTUAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LIVER; MICE; MICE, INBRED C57BL; MODELS, STATISTICAL; MULTIGENE FAMILY; MUSCLES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; TOXICOLOGY;

EID: 84871305336     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048238     Document Type: Article

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