-
1
-
-
0034095165
-
Short-chain dehydrogenases/reductases in retina
-
Haeseleer F., Palczewski K. Short-chain dehydrogenases/reductases in retina. Meth Enzymol: 2000; 316 372 383
-
(2000)
Meth Enzymol
, vol.316
, pp. 372-383
-
-
Haeseleer, F.1
Palczewski, K.2
-
2
-
-
33947216707
-
Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity
-
Lukacik P., Keller B., Bunkoczi G., Kavanagh K. L., Lee W. H., Adamski J., Oppermann U. Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity. Biochem J: 2007; 402 419 427
-
(2007)
Biochem J
, vol.402
, pp. 419-427
-
-
Lukacik, P.1
Keller, B.2
Bunkoczi, G.3
Kavanagh, K.L.4
Lee, W.H.5
Adamski, J.6
Oppermann, U.7
-
3
-
-
69249127192
-
Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17beta-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells
-
Sherbet D. P., Guryev O. L., Papari-Zareei M., Mizrachi D., Rambally S., Akbar S., Anchus R. J. Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17beta-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells. Endocrinology: 2009; 150 4154 4162
-
(2009)
Endocrinology
, vol.150
, pp. 4154-4162
-
-
Sherbet, D.P.1
Guryev, O.L.2
Papari-Zareei, M.3
Mizrachi, D.4
Rambally, S.5
Akbar, S.6
Anchus, R.J.7
-
4
-
-
29544439001
-
Comparison of in vitro and in vivo screening models for androgenic and estrogenic activities
-
Sonneveld E., Riteco JA C., Jansen H. J., Pieterse B., Brouwer A., Schoonen W. G., van der Burg B. Comparison of in vitro and in vivo screening models for androgenic and estrogenic activities. Toxicol Sci: 2006; 89 173 187
-
(2006)
Toxicol Sci
, vol.89
, pp. 173-187
-
-
Sonneveld, E.1
Riteco, J.A.C.2
Jansen, H.J.3
Pieterse, B.4
Brouwer, A.5
Schoonen, W.G.6
Van Der Burg, B.7
-
5
-
-
53849119147
-
Design and validation of specific inhibitors of 17b-hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis
-
Day J. M., Tutill H. J., Purohit A., Reed M. J. Design and validation of specific inhibitors of 17b-hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis. Endocr Rel Cancer: 2008; 15 665 692
-
(2008)
Endocr Rel Cancer
, vol.15
, pp. 665-692
-
-
Day, J.M.1
Tutill, H.J.2
Purohit, A.3
Reed, M.J.4
-
6
-
-
42949100377
-
Androgen biosynthetic pathways in the human prostate. Best Practice and Research
-
Luu-The V., Bélanger A., Labrie F. Androgen biosynthetic pathways in the human prostate. Best Practice and Research. Clin Endocrinol Metab: 2008; 22 207 221
-
(2008)
Clin Endocrinol Metab
, vol.22
, pp. 207-221
-
-
Luu-The, V.1
Bélanger, A.2
Labrie, F.3
-
7
-
-
0035931119
-
Pan1b (17βHSD11)-enzymatic activity and distribution in the lung
-
Brereton P., Suzuki T., Sasano H., Li K., Duarte C., Obeyesekere V., Haeseleer F., Palczewski K., Smith I., Komesaroff P., Krozowski Z. Pan1b (17βHSD11)-enzymatic activity and distribution in the lung. Mol Cell Endocrinol: 2001; 171 111 117
-
(2001)
Mol Cell Endocrinol
, vol.171
, pp. 111-117
-
-
Brereton, P.1
Suzuki, T.2
Sasano, H.3
Li, K.4
Duarte, C.5
Obeyesekere, V.6
Haeseleer, F.7
Palczewski, K.8
Smith, I.9
Komesaroff, P.10
Krozowski, Z.11
-
8
-
-
0027930787
-
Male pseudohermaphroditism caused by mutations of testicular 17-beta-hydroxysteroid dehydrogenase-3
-
Geissler W. M., Davis D. L., Wu L., Bradshaw K. D., Patel S., Mendonca B. B., Elliston K. O., Wilson J. D., Russell D. W., Andersson S. Male pseudohermaphroditism caused by mutations of testicular 17-beta-hydroxysteroid dehydrogenase-3. Nature Gen: 1994; 7 34 39
-
(1994)
Nature Gen
, vol.7
, pp. 34-39
-
-
Geissler, W.M.1
Davis, D.L.2
Wu, L.3
Bradshaw, K.D.4
Patel, S.5
Mendonca, B.B.6
Elliston, K.O.7
Wilson, J.D.8
Russell, D.W.9
Andersson, S.10
-
9
-
-
0032570674
-
Characterization of rat 17b-hydroxysteroid dehydrogenase type 1 gene and mRNA transcripts
-
Akinola L. A., Poutanen M., Peltoketo H., Vihko R., Vihko P. Characterization of rat 17b-hydroxysteroid dehydrogenase type 1 gene and mRNA transcripts. Gene: 1998; 208 229 238
-
(1998)
Gene
, vol.208
, pp. 229-238
-
-
Akinola, L.A.1
Poutanen, M.2
Peltoketo, H.3
Vihko, R.4
Vihko, P.5
-
10
-
-
0027225486
-
Expression cloning and characterization of human 17-beta-hydroxysteroid dehydrogenase type-2, a microsomal-enzyme possessing 20-alpha-hydroxysteroid dehydrogenase-activity
-
Wu L., Einstein M., Geissler W. M., Chan H. K., Elliston K. O., Andrsson S. Expression cloning and characterization of human 17-beta-hydroxysteroid dehydrogenase type-2, a microsomal-enzyme possessing 20-alpha-hydroxysteroid dehydrogenase-activity. J Biol Chem: 1993; 268 12964 12969
-
(1993)
J Biol Chem
, vol.268
, pp. 12964-12969
-
-
Wu, L.1
Einstein, M.2
Geissler, W.M.3
Chan, H.K.4
Elliston, K.O.5
Andrsson, S.6
-
11
-
-
0030991226
-
Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate
-
Biswas M. G., Russell D. W. Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate. J Biol Chem: 1997; 272 15959 15966
-
(1997)
J Biol Chem
, vol.272
, pp. 15959-15966
-
-
Biswas, M.G.1
Russell, D.W.2
-
12
-
-
0030454449
-
Peroxisomes contain an enzyme with 17 beta-estradiol dehydrogenase, fatty acid hydratase/dehydrogenase, and sterol carrier activity
-
Markus M., Husen B., Leenders F., Seedorf U., Jungblut P. W., Hall P. H., Adamski J. Peroxisomes contain an enzyme with 17 beta-estradiol dehydrogenase, fatty acid hydratase/dehydrogenase, and sterol carrier activity. Ann N Y Acad Sci: 1996; 804 691 693
-
(1996)
Ann N y Acad Sci
, vol.804
, pp. 691-693
-
-
Markus, M.1
Husen, B.2
Leenders, F.3
Seedorf, U.4
Jungblut, P.W.5
Hall, P.H.6
Adamski, J.7
-
13
-
-
0037470063
-
Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade
-
Moon Y. A., Horton J. D. Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade. J Biol Chem: 2003; 278 7335 7343
-
(2003)
J Biol Chem
, vol.278
, pp. 7335-7343
-
-
Moon, Y.A.1
Horton, J.D.2
-
14
-
-
0032727093
-
Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7(1)
-
Krazeisen A., Breitling R., Imai K., Fritz S., Moller G., Adamski J. Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7(1). FEBS Lett: 1999; 460 373 379
-
(1999)
FEBS Lett
, vol.460
, pp. 373-379
-
-
Krazeisen, A.1
Breitling, R.2
Imai, K.3
Fritz, S.4
Moller, G.5
Adamski, J.6
-
15
-
-
0344741467
-
Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: Characterization of multifunctional 3alpha/7alpha/7beta/17beta/20beta/21-HSD
-
Shafqat N., Marschall H. U., Filling C., Nordling E., Wu X. Q., Bjork L., Thyberg J., Martensson E., Salim S., Jornvall H., Oppermann U. Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization of multifunctional 3alpha/7alpha/7beta/ 17beta/20beta/21-HSD. Biochem J: 2003; 376 49 60
-
(2003)
Biochem J
, vol.376
, pp. 49-60
-
-
Shafqat, N.1
Marschall, H.U.2
Filling, C.3
Nordling, E.4
Wu, X.Q.5
Bjork, L.6
Thyberg, J.7
Martensson, E.8
Salim, S.9
Jornvall, H.10
Oppermann, U.11
-
16
-
-
0035941343
-
Molecular characterization of a mouse short chain dehydrogenase/reductase active with all-trans-retinol in intact cells, mRDH1
-
Zhang M., Chen W., Smith S. M., Napoli J. L. Molecular characterization of a mouse short chain dehydrogenase/reductase active with all-trans-retinol in intact cells, mRDH1. J Biol Chem: 2001; 276 44083 44090
-
(2001)
J Biol Chem
, vol.276
, pp. 44083-44090
-
-
Zhang, M.1
Chen, W.2
Smith, S.M.3
Napoli, J.L.4
-
17
-
-
84871189160
-
-
Bellino F.L. Daynes R.A. Hornsby P.J. Lavrin D.H. Nestler J.E. (eds.). Dehydroepiandrosterone New York New York Acad Sciences
-
Labrie F., Belanger A., Simard J., LuuThe V., Labrie C. DHEA and peripheral androgen and estrogen formation: Intracrinology. In: Bellino F. L., Daynes R. A., Hornsby P. J., Lavrin D. H., Nestler J. E. (eds.). Dehydroepiandrosterone. New York New York Acad Sciences: 1995; 1628
-
(1995)
DHEA and Peripheral Androgen and Estrogen Formation: Intracrinology
, pp. 1628
-
-
Labrie, F.1
Belanger, A.2
Simard, J.3
Luuthe, V.4
Labrie, C.5
-
18
-
-
5644246147
-
17b-Hydroxysteroid dehydrogenase type 1 is an independent prognostic marker in breast cancer
-
Oduwole O. O., Li Y., Isomaa V. V., Mäntyniemi A., Pulkka A. E., Soini Y., Vihko P. T. 17b-Hydroxysteroid dehydrogenase type 1 is an independent prognostic marker in breast cancer. Cancer Res: 2004; 64 7604 7609
-
(2004)
Cancer Res
, vol.64
, pp. 7604-7609
-
-
Oduwole, O.O.1
Li, Y.2
Isomaa, V.V.3
Mäntyniemi, A.4
Pulkka, A.E.5
Soini, Y.6
Vihko, P.T.7
-
19
-
-
43049108105
-
Amplification of HSD17B1 has prognostic significance in postmenopausal breast cancer
-
Gunnarsson C., Jerevall P. L., Hammar K., Olsson B., Nordenskjöld B., Jansson A., Stål O. Amplification of HSD17B1 has prognostic significance in postmenopausal breast cancer. Breast Cancer Res Treatment: 2008; 108 35 41
-
(2008)
Breast Cancer Res Treatment
, vol.108
, pp. 35-41
-
-
Gunnarsson, C.1
Jerevall, P.L.2
Hammar, K.3
Olsson, B.4
Nordenskjöld, B.5
Jansson, A.6
Stål, O.7
-
20
-
-
84871223880
-
A validated and rapid high-performance liquid chromatography method for the quantification of conversion of radio-labelled sex steroids
-
Sivik T., Vikingsson S., Gréen H., Jansson A. A validated and rapid high-performance liquid chromatography method for the quantification of conversion of radio-labelled sex steroids. Horm Mol Biol Clin Invest: 2010; 3 375 381
-
(2010)
Horm Mol Biol Clin Invest
, vol.3
, pp. 375-381
-
-
Sivik, T.1
Vikingsson, S.2
Gréen, H.3
Jansson, A.4
-
21
-
-
33845728020
-
17b-hydroxysteroid dehydrogenase 14 affects estradiol levels in breast cancer cells and is a prognostic marker in estrogen receptor-positive breast cancer
-
Jansson A. K., Gunnarsson C., Cohen M., Sivik T., Stål O. 17b-hydroxysteroid dehydrogenase 14 affects estradiol levels in breast cancer cells and is a prognostic marker in estrogen receptor-positive breast cancer. Cancer Res: 2006; 66 11471 11477
-
(2006)
Cancer Res
, vol.66
, pp. 11471-11477
-
-
Jansson, A.K.1
Gunnarsson, C.2
Cohen, M.3
Sivik, T.4
Stål, O.5
-
22
-
-
84863707833
-
17beta-hydroxysteroid dehydrogenase type 14 is a predictive marker for tamoxifen response in oestrogen receptor positive breast cancer
-
Sivik T., Gunnarsson C., Fornander T., Nordenskjold B., Skoog L., Stal O., Jansson A. 17beta-hydroxysteroid dehydrogenase type 14 is a predictive marker for tamoxifen response in oestrogen receptor positive breast cancer. PLoS One: 2012; 7 e40568
-
(2012)
PLoS One
, vol.7
-
-
Sivik, T.1
Gunnarsson, C.2
Fornander, T.3
Nordenskjold, B.4
Skoog, L.5
Stal, O.6
Jansson, A.7
-
23
-
-
0029817523
-
Aromatase and 17b-hydroxysteroid dehydrogenase type 1 in human breast carcinoma
-
Sasano H., Frost A. R., Saitoh R., Harada N., Poutanen M., Vihko R., Bulun S. E., Silverberg S. G., Nagura H. Aromatase and 17b-hydroxysteroid dehydrogenase type 1 in human breast carcinoma. J Clin Endocrinol Metabol: 1996; 81 4042 4046
-
(1996)
J Clin Endocrinol Metabol
, vol.81
, pp. 4042-4046
-
-
Sasano, H.1
Frost, A.R.2
Saitoh, R.3
Harada, N.4
Poutanen, M.5
Vihko, R.6
Bulun, S.E.7
Silverberg, S.G.8
Nagura, H.9
-
24
-
-
0032886786
-
In vivo and in vitro expression of steroid-converting enzymes in human breast tumours: Associations with interleukin-6
-
Speirs V., Walton D. S., Hall M. C., Atkin S. L. In vivo and in vitro expression of steroid-converting enzymes in human breast tumours: associations with interleukin-6. Br J Cancer: 1999; 81 690 695
-
(1999)
Br J Cancer
, vol.81
, pp. 690-695
-
-
Speirs, V.1
Walton, D.S.2
Hall, M.C.3
Atkin, S.L.4
-
25
-
-
0031732665
-
Activity and gene expression of 17beta-hydroxysteroid dehydrogenase type i in primary cultures of epithelial and stromal cells derived from normal and tumourous human breast tissue: The role of IL-8
-
Speirs V., Green A. R., Atkin S. L. Activity and gene expression of 17beta-hydroxysteroid dehydrogenase type I in primary cultures of epithelial and stromal cells derived from normal and tumourous human breast tissue: the role of IL-8. J Steroid Biochem Mol Biol: 1998; 67 267 274
-
(1998)
J Steroid Biochem Mol Biol
, vol.67
, pp. 267-274
-
-
Speirs, V.1
Green, A.R.2
Atkin, S.L.3
-
26
-
-
17944382588
-
17 beta-Hydroxysteroid dehydrogenase type 2 expression and enzyme activity in the human gastrointestinal tract
-
Sano T., Hirasawa G., Takeyama J., Darnel A. D., Suzuki T., Moriya T., Kato K., Sekine H., Ohara S., Shimosegawa T., Nakamura J., Yoshihama M., Harada N., Sasano H. 17 beta-Hydroxysteroid dehydrogenase type 2 expression and enzyme activity in the human gastrointestinal tract. Clin Sci (Lond): 2001; 101 485 491
-
(2001)
Clin Sci (Lond)
, vol.101
, pp. 485-491
-
-
Sano, T.1
Hirasawa, G.2
Takeyama, J.3
Darnel, A.D.4
Suzuki, T.5
Moriya, T.6
Kato, K.7
Sekine, H.8
Ohara, S.9
Shimosegawa, T.10
Nakamura, J.11
Yoshihama, M.12
Harada, N.13
Sasano, H.14
-
27
-
-
0033930878
-
Oestrogen inactivation in the colon: Analysis of the expression and regulation of 17beta-hydroxysteroid dehydrogenase isozymes in normal colon and colonic cancer
-
English M. A., Hughes S. V., Kane K. F., Langman M. J., Stewart P. M., Hewison M. Oestrogen inactivation in the colon: analysis of the expression and regulation of 17beta-hydroxysteroid dehydrogenase isozymes in normal colon and colonic cancer. Br J Cancer: 2000; 83 550 558
-
(2000)
Br J Cancer
, vol.83
, pp. 550-558
-
-
English, M.A.1
Hughes, S.V.2
Kane, K.F.3
Langman, M.J.4
Stewart, P.M.5
Hewison, M.6
-
28
-
-
49749125298
-
Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system
-
Azzarello J., Fung K. M., Lin H. K. Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system. J Histochem Cytochem: 2008; 56 853 861
-
(2008)
J Histochem Cytochem
, vol.56
, pp. 853-861
-
-
Azzarello, J.1
Fung, K.M.2
Lin, H.K.3
-
29
-
-
33646801655
-
Systemic distribution and tissue localizations of human 17beta-hydroxysteroid dehydrogenase type 12
-
Sakurai N., Miki Y., Suzuki T., Watanabe K., Narita T., Ando K., Yung TM C., Aoki D., Sasano H., Handa H. Systemic distribution and tissue localizations of human 17beta-hydroxysteroid dehydrogenase type 12. J Steroid Biochem Mol Biol: 2006; 99 174 181
-
(2006)
J Steroid Biochem Mol Biol
, vol.99
, pp. 174-181
-
-
Sakurai, N.1
Miki, Y.2
Suzuki, T.3
Watanabe, K.4
Narita, T.5
Ando, K.6
Yung, T.M.C.7
Aoki, D.8
Sasano, H.9
Handa, H.10
-
30
-
-
0038070588
-
17β-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells
-
Chai Z., Brereton P., Suzuki T., Sasano H., Obeyesekere V., Escher G., Saffery R., Fuller P., Enriquez C., Krozowski Z. 17β-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells. Endocrinology: 2003; 144 2084 2091
-
(2003)
Endocrinology
, vol.144
, pp. 2084-2091
-
-
Chai, Z.1
Brereton, P.2
Suzuki, T.3
Sasano, H.4
Obeyesekere, V.5
Escher, G.6
Saffery, R.7
Fuller, P.8
Enriquez, C.9
Krozowski, Z.10
-
31
-
-
77951638901
-
Expression of AKR1C3 in renal cell carcinoma, papillary urothelial carcinoma, and Wilms' tumor
-
Azzarello J. T., Lin H. K., Gherezghiher A., Zakharov V., Yu Z., Kropp B. P., Culkin D. J., Penning T. M., Fung K. M. Expression of AKR1C3 in renal cell carcinoma, papillary urothelial carcinoma, and Wilms' tumor. Int J Clin Exp Pathol: 2009; 3 147 155
-
(2009)
Int J Clin Exp Pathol
, vol.3
, pp. 147-155
-
-
Azzarello, J.T.1
Lin, H.K.2
Gherezghiher, A.3
Zakharov, V.4
Yu, Z.5
Kropp, B.P.6
Culkin, D.J.7
Penning, T.M.8
Fung, K.M.9
-
32
-
-
34347339478
-
17beta-estradiol synthesis in the adult male rat retina
-
Cascio C., Russo D., Drago G., Galizzi G., Passantino R., Guarneri R., Guarneri P. 17beta-estradiol synthesis in the adult male rat retina. Exp Eye Res: 2007; 85 166 172
-
(2007)
Exp Eye Res
, vol.85
, pp. 166-172
-
-
Cascio, C.1
Russo, D.2
Drago, G.3
Galizzi, G.4
Passantino, R.5
Guarneri, R.6
Guarneri, P.7
-
33
-
-
0035931125
-
Evolution of 17beta-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action
-
Baker M. E. Evolution of 17beta-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action. Mol Cell Endocrinol: 2001; 171 211 215
-
(2001)
Mol Cell Endocrinol
, vol.171
, pp. 211-215
-
-
Baker, M.E.1
-
34
-
-
0030991226
-
Expression cloning and characterization of oxidative 17 beta- and 3 alpha-hydroxysteroid dehydrogenases from rat and human prostate
-
Biswas M. G., Russell D. W. Expression cloning and characterization of oxidative 17 beta- and 3 alpha-hydroxysteroid dehydrogenases from rat and human prostate. J Biol Chem: 1997; 272 15959 15966
-
(1997)
J Biol Chem
, vol.272
, pp. 15959-15966
-
-
Biswas, M.G.1
Russell, D.W.2
-
35
-
-
77953083038
-
Molecular framework of steroid/retinoid discrimination in 17beta-hydroxysteroid dehydrogenase type 1 and photoreceptor-associated retinol dehydrogenase
-
Haller F., Moman E., Hartmann R. W., Adamski J., Mindnich R. Molecular framework of steroid/retinoid discrimination in 17beta-hydroxysteroid dehydrogenase type 1 and photoreceptor-associated retinol dehydrogenase. J Mol Biol: 2010; 399 255 267
-
(2010)
J Mol Biol
, vol.399
, pp. 255-267
-
-
Haller, F.1
Moman, E.2
Hartmann, R.W.3
Adamski, J.4
Mindnich, R.5
-
36
-
-
79955788943
-
An ADIOL-ERbeta-CtBP transrepression pathway negatively regulates microglia-mediated inflammation
-
Saijo K., Collier J. G., Li A. C., Katzenellenbogen J. A., Glass C. K. An ADIOL-ERbeta-CtBP transrepression pathway negatively regulates microglia-mediated inflammation. Cell: 2011; 145 584 595
-
(2011)
Cell
, vol.145
, pp. 584-595
-
-
Saijo, K.1
Collier, J.G.2
Li, A.C.3
Katzenellenbogen, J.A.4
Glass, C.K.5
-
37
-
-
3543068881
-
Human 17beta-hydroxysteroid dehydrogenases types 1, 2, and 3 catalyze bi-directional equilibrium reactions, rather than unidirectional metabolism, in HEK-293 cells
-
Khan N., Sharma K. K., Andersson S., Auchus R. J. Human 17beta-hydroxysteroid dehydrogenases types 1, 2, and 3 catalyze bi-directional equilibrium reactions, rather than unidirectional metabolism, in HEK-293 cells. Arch Biochem Biophys: 2004; 429 50 59
-
(2004)
Arch Biochem Biophys
, vol.429
, pp. 50-59
-
-
Khan, N.1
Sharma, K.K.2
Andersson, S.3
Auchus, R.J.4
|