Lipid peroxides and glutathione status in human progenitor mononuclear (U937) cells following exposure to low doses of nickel and copper

Drug and Chemical Toxicology

Volumn 36, Issue 2, 2013, Pages 155-162

  Boadi, William Y ^a   Harris, Shalandus ^a   Anderson, Justin B ^a   Adunyah, Samuel E ^b  

^a TENNESSEE STATE UNIVERSITY   (United States)

^b MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

Copper; Glutathione; Lipid peroxides; Nickel; Thiobarbituric acid assay; U937 cells

Indexed keywords

COPPER; EDETIC ACID; GLUTATHIONE; LIPID PEROXIDE; METAL ION; NICKEL; THIOBARBITURIC ACID; WATER;

ARTICLE; ASSAY; CELL LEVEL; CONTROLLED STUDY; HUMAN; HUMAN CELL; LETHALITY; MONONUCLEAR CELL; STEM CELL;

COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; EDETIC ACID; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; LEUKOCYTES, MONONUCLEAR; LIPID PEROXIDATION; NICKEL; THIOBARBITURATES; U937 CELLS;

EID: 84871244617     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.3109/01480545.2012.660947     Document Type: Article

References (32)

1. Adunyah, S. E., Wheeler, B. J. and Cooper, R. S. (1997). Evidence for the involvement of LCK and MAP kinase (ERK-1) in the signal transduction mechanism of interleukin-15. Biochem Biophys Res Commun 232:754-758.
2. Bains, J. S. and Shaw, C. A. (1997). Neurodegenerative disorders in humans: The role of glutathione in oxidative stress-mediated neuronal death. Brain Res Brain Res Rev 25:335-358.
3. Bal, W. and Kasprzak, K. S. (2002). Induction of oxidative DNA damage by carcinogenic metals. Toxicol Lett 127:55-62.
4. Boadi, W. Y., Iyere, P. A. and Adunyah, S. E. (2003). Effect of quercetin and genistein on copper- and iron-induced lipid peroxidation in methyl linolenate. J Appl Toxicol 23:363-369.
5. Boadi, W. Y., Iyere, P. A. and Adunyah, S. E. (2005). In vitro exposure to quercetin and genistein alters lipid peroxides and prevents the loss of glutathione in human progenitor mononuclear (U937) cells. J Appl Toxicol 25:82-88.
6. Cartañà, J., Romeu, A. and Arola, L. (1992). Effects of copper, cadmium and nickel on liver and kidney glutathione redox cycle of rats (Rattus sp.). Comp Biochem Physiol C, Comp Pharmacol Toxicol 101:209-213.
7. Choi, J., Liu, R. M., Kundu, R. K., Sangiorgi, F., Wu, W., Maxson, R. and Forman, H. J. (2000). Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice. J Biol Chem 275:3693-3698.
8. Duthie, S. J., Collins, A. R., Duthie, G. G. and Dobson, V. L. (1997).Quercetin and myricetin protect against hydrogen peroxideinduced DNA damage (strand breaks and oxidised pyrimidines) in human lymphocytes. Mutat Res 393:223-231.
9. García-Fernández, A. J., Bayoumi, A. E., Pérez-Pertejo, Y., Motas, M., Reguera, R. M., Ordóñez, C., Balaña-Fouce, R. and Ordóñez, D. (2002). Alterations of the glutathione-redox balance induced by metals in CHO-K1 cells. Comp Biochem Physiol C Toxicol Pharmacol 132:365-373.
10. Hansen, J. M., Zhang, H. and Jones, D. P. (2006). Differential oxidation of thioredoxin-1, thioredoxin-2, and glutathione by metal ions. Free Radic Biol Med 40:138-145.
11. Georgopoulos, P. G., Wang, S. W., Georgopoulos, I. G., Yonone-Lioy, M. J. and Lioy, P. J. (2006). Assessment of human exposure to copper: A case study using the NHEXAS database. J Expo Sci Environ Epidemiol 16:397-409.
12. Grandjean, P. (1984). Human exposure to nickel. IARC Sci Publ 53:469-485.
13. Kasprzak, K. S., Waalkes, M. P. and Poirier, L. A. (1986). Antagonism by essential divalent metals and amino acids of nickel(II)-DNA binding in vitro. Toxicol Appl Pharmacol 82:336-343.
14. Kennedy, L. J., Moore, K.Jr, Caulfield, J. L., Tannenbaum, S. R. and Dedon, P. C. (1997). Quantitation of 8-oxoguanine and strand breaks produced by four oxidizing agents. Chem Res Toxicol 10:386-392.
15. Kilic, D., Sayan, H., Gönül, B. and Egehan, I. (2000). The effect of granulocyte macrophage-colony stimulating factor on glutathione and lipid peroxidation in a rat model. Eur J Surg Oncol 26:701-704.
16. Lakritz, J., Plopper, C. G. and Buckpitt, A. R. (1997). Validated highperformance liquid chromatography-electrochemical method for determination of glutathione and glutathione disulfide in small tissue samples. Anal Biochem 247:63-68.
17. Li, Y., Liu, J., Liu, Y. and Li, X. (2009). Effects of EDTA on mechanism of lead accumulation in Typha orientalis Presl. Bull Environ Contam Toxicol 83:553-557.
18. Li, Y., Maher, P. and Schubert, D. (1997). A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron 19:453-463.
19. Li, W., Zhao, Y. and Chou, I. N. (1993). Alterations in cytoskeletal protein sulfhydryls and cellular glutathione in cultured cells exposed to cadmium and nickel ions. Toxicology 77: 65-79.
20. Lin, W.-C., Liao, Y.-C., Liau, M.-C. (2003). Effect of CGA-II on cell viability, lipid peroxidation, glutathione concentration, and its related enzyme activities in primary rat hepatocytes. Am J Chinese Med 31:415-423.
21. Minotti, G. (1993). Sources and role of iron in lipid peroxidation. Chem Res Toxicol 6:134-146.
22. Misra, M., Rodriguez, R. E. and Kasprzak, K. S. (1990). Nickel induced lipid peroxidation in the rat: Correlation with nickel effect on antioxidant defense systems. Toxicology 64:1-17.
23. Rimbach, G., Gohil, K., Matsugo, S., Moini, H., Saliou, C., Virgili, F., Weber, S. U. and Packer, L. (2001). Induction of glutathione synthesis in human keratinocytes by Ginkgo biloba extract (EGb761). Biofactors 15:39-52.
24. Sorokin, V. A., Valeev, V. A., Gladchenko, G. O., Sysa, I. V., Blagoi, Y. P.and Volchok, I. V. (1996). Interaction of bivalent copper, nickel, manganese ions with native DNA and its monomers. J Inorg Biochem 63:79-98.
25. Stinson, T. J., Jaw, S., Jeffery, E. H. and Plewa, M. J. (1992). The relationship between nickel chloride-induced peroxidation and DNA strand breakage in rat liver. Toxicol Appl Pharmacol 117:98-103.
26. Stohs, J. S., Bacchi, D. (1995). Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med 18:321-336.
27. Subramaniam, S. V., Cooper, R. S., Adunyah, S. E. (1999). Interleukin-17 induces rapid tyrosine phosphorylation and activation of raf-1 kinase in human monocytic progenitor cell line U937. Biochem Biophys Res Commun 262:14-19.
28. Tamura, H., Kitta, K., Shibamoto, T. (1991). Formation of reactive aldehydes from fatty acids in a Fe2+ /H2O2 oxidation system. J Agric Food Chem 39:439-442.
29. Valko, M., Morris, H. and Cronin, M. T. (2005). Metals, toxicity and oxidative stress. Curr Med Chem 12: 1161-1208.
30. Wataha, J. C., Lewis, J. B., Lockwood, P. E. and Rakich, D. R. (2000).Effect of dental metal ions on glutathione levels in THP-1 human monocytes. J Oral Rehabil 27:508-516.
31. White, A. R. and Cappai, R. (2003). Neurotoxicity from glutathione depletion is dependent on extracellular trace copper. J Neurosci Res 15:889-897.
32. Winterbourn, C. C. (1993). Superoxide as an intracellular radical sink. Free Radic Biol Med 14:85-90.