메뉴 건너뛰기




Volumn 56, Issue 1, 2013, Pages 118-122

Revisiting the predictors of a sustained virologic response in the era of direct-acting antiviral therapy for hepatitis C virus

Author keywords

direct acting antivirals; hepatitis C; peginterferon; prediction; ribavirin

Indexed keywords

BOCEPREVIR; DANOPREVIR; FALDAPREVIR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 28B; INTERLEUKIN 8; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MERICITABINE; TELAPREVIR; VIRUS RNA; VITAMIN D;

EID: 84871231459     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cis843     Document Type: Article
Times cited : (20)

References (50)
  • 1
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • Manns MP, McHutchison JG, Gordon SC, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001; 358:958-65.
    • (2001) Lancet , vol.358 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3
  • 2
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Fried MW, Shiffman ML, Reddy KR, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002; 347:975-82.
    • (2002) N Engl J Med , vol.347 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 3
    • 84865494240 scopus 로고    scopus 로고
    • Factors that predict response of patients with hepatitis C virus infection to boceprevir
    • Poordad F, Bronowicki JP, Gordon SC, et al. Factors that predict response of patients with hepatitis C virus infection to boceprevir. Gastroenterology 2012; 143:608-18.
    • (2012) Gastroenterology , vol.143 , pp. 608-618
    • Poordad, F.1    Bronowicki, J.P.2    Gordon, S.C.3
  • 4
    • 2442665224 scopus 로고    scopus 로고
    • Peginterferon alfa-2b and ribavirin for the treatment of chronic hepatitis C in blacks and non-Hispanic whites
    • Atlantic Coast Hepatitis Treatment Group
    • Muir AJ, Bornstein JD, Killenberg PG, Atlantic Coast Hepatitis Treatment Group. Peginterferon alfa-2b and ribavirin for the treatment of chronic hepatitis C in blacks and non-Hispanic whites. N Engl J Med 2004; 350:2265-71.
    • (2004) N Engl J Med , vol.350 , pp. 2265-2271
    • Muir, A.J.1    Bornstein, J.D.2    Killenberg, P.G.3
  • 5
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment induced viral clearance
    • Ge D, Fellay J, Thompson AJ, et al. Genetic variation in IL28B predicts hepatitis C treatment induced viral clearance. Nature 2009; 461:399-401.
    • (2009) Nature , vol.461 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3
  • 6
    • 80053301609 scopus 로고    scopus 로고
    • Vitamin D levels may explain the racial differences in response rates to antiviral therapy for chronic hepatitis C
    • Ji HF. Vitamin D levels may explain the racial differences in response rates to antiviral therapy for chronic hepatitis C. Hepatology 2011; 54:1489.
    • (2011) Hepatology , vol.54 , pp. 1489
    • Ji, H.F.1
  • 7
    • 84855697857 scopus 로고    scopus 로고
    • Optimal treatment duration for patients with HCV genotype 1 infection
    • Ferenci P. Optimal treatment duration for patients with HCV genotype 1 infection. J Viral Hepatitis 2012; 19(suppl 1):7-13.
    • (2012) J Viral Hepatitis , vol.19 , Issue.SUPPL. 1 , pp. 7-13
    • Ferenci, P.1
  • 8
    • 79959438789 scopus 로고    scopus 로고
    • Telaprevir for previously untreated chronic hepatitis C virus infection
    • Jacobson IM, McHutchison JG, Dusheiko G, et al. Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med 2011; 364:2405-16.
    • (2011) N Engl J Med , vol.364 , pp. 2405-2416
    • Jacobson, I.M.1    McHutchison, J.G.2    Dusheiko, G.3
  • 9
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir for untreated chronic HCV genotype 1 infection
    • Poordad F, McCone J Jr, Bacon BR, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011; 364:1195-206.
    • (2011) N Engl J Med , vol.364 , pp. 1195-1206
    • Poordad, F.1    McCone Jr., J.2    Bacon, B.R.3
  • 10
    • 79959381354 scopus 로고    scopus 로고
    • Telaprevir for retreatment of HCV infection
    • Zeuzem S, Andreone P, Pol S, et al. Telaprevir for retreatment of HCV infection. N Engl J Med 2011; 364:2417-28.
    • (2011) N Engl J Med , vol.364 , pp. 2417-2428
    • Zeuzem, S.1    Andreone, P.2    Pol, S.3
  • 11
    • 79953176289 scopus 로고    scopus 로고
    • Boceprevir for previously treated chronic HCV genotype 1 infection
    • Bacon BR, Gordon SC, Lawitz E, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011; 364:1207-17.
    • (2011) N Engl J Med , vol.364 , pp. 1207-1217
    • Bacon, B.R.1    Gordon, S.C.2    Lawitz, E.3
  • 12
    • 77956268664 scopus 로고    scopus 로고
    • Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing
    • Cheng WS, Roberts SK, McCaughan G, et al. Low virological response and high relapse rates in hepatitis C genotype 1 patients with advanced fibrosis despite adequate therapeutic dosing. J Hepatol 2010; 53:616-23.
    • (2010) J Hepatol , vol.53 , pp. 616-623
    • Cheng, W.S.1    Roberts, S.K.2    McCaughan, G.3
  • 13
    • 79959353386 scopus 로고    scopus 로고
    • Portal pressure predicts outcome and safety of antiviral therapy in cirrhotic patients with HCV infection
    • Reiberger T, Rutter K, Ferlitsch A, et al. Portal pressure predicts outcome and safety of antiviral therapy in cirrhotic patients with HCV infection. Clin Gastroenterol Hepatol 2011; 9:602-8.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 602-608
    • Reiberger, T.1    Rutter, K.2    Ferlitsch, A.3
  • 14
    • 17944381054 scopus 로고    scopus 로고
    • Expression of liver steatosis in hepatitis C virus infection and pattern of response to alpha-interferon
    • Rubbia-Brandt L, Giostra E, Mentha G, Quadri R, Negro F. Expression of liver steatosis in hepatitis C virus infection and pattern of response to alpha-interferon. J Hepatol 2001; 35:307.
    • (2001) J Hepatol , vol.35 , pp. 307
    • Rubbia-Brandt, L.1    Giostra, E.2    Mentha, G.3    Quadri, R.4    Negro, F.5
  • 15
    • 0043037223 scopus 로고    scopus 로고
    • High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C
    • Bressler BL, Guindi M, Tomlinson G, et al. High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C. Hepatology 2003; 38:639-44.
    • (2003) Hepatology , vol.38 , pp. 639-644
    • Bressler, B.L.1    Guindi, M.2    Tomlinson, G.3
  • 16
    • 15744381704 scopus 로고    scopus 로고
    • Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients
    • Romero-Gomez M, Del Mar Viloria M, Andrade RJ, et al. Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients. Gastroenterology 2005; 128: 636-41.
    • (2005) Gastroenterology , vol.128 , pp. 636-641
    • Romero-Gomez, M.1    Del Mar Viloria, M.2    Andrade, R.J.3
  • 17
    • 78649817575 scopus 로고    scopus 로고
    • Danoprevir, an HCV NS3/4A protease inhibitor, improves insulin sensitivity in patients with genotype 1 chronic hepatitis C
    • Moucari R, Forestier N, Larrey D, et al. Danoprevir, an HCV NS3/4A protease inhibitor, improves insulin sensitivity in patients with genotype 1 chronic hepatitis C. Gut 2010; 59:1694-8.
    • (2010) Gut , vol.59 , pp. 1694-1698
    • Moucari, R.1    Forestier, N.2    Larrey, D.3
  • 18
    • 79251554986 scopus 로고    scopus 로고
    • Telaprevir administered every 8 or 12 hours in combination with ribavirin and either peginterferon alfa-2a or alfa-2b: Results from a randomised trial in treatment-naive patients with genotype 1 chronic hepatitis C
    • Marcellin M, Forns X, Goeser T, et al. Telaprevir administered every 8 or 12 hours in combination with ribavirin and either peginterferon alfa-2a or alfa-2b: results from a randomised trial in treatment-naive patients with genotype 1 chronic hepatitis C. Gastroenterology 2011; 140:459-68.
    • (2011) Gastroenterology , vol.140 , pp. 459-468
    • Marcellin, M.1    Forns, X.2    Goeser, T.3
  • 19
    • 84866060640 scopus 로고    scopus 로고
    • Insulin resistance and response to telaprevir plus peginterferon alfa and ribavirin in treatment-naive, genotype 1 HCV patients
    • Serfaty L, Forns X, Goeser T, et al. Insulin resistance and response to telaprevir plus peginterferon alfa and ribavirin in treatment-naive, genotype 1 HCV patients. Gut 2012; 61:1473-80.
    • (2012) Gut , vol.61 , pp. 1473-1480
    • Serfaty, L.1    Forns, X.2    Goeser, T.3
  • 20
    • 38649120719 scopus 로고    scopus 로고
    • Insulin resistance in chronic hepatitis C: Association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis
    • Moucari R, Asselah T, Cazals-Hatem D, et al. Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis. Gastroenterology 2008; 134:416-23.
    • (2008) Gastroenterology , vol.134 , pp. 416-423
    • Moucari, R.1    Asselah, T.2    Cazals-Hatem, D.3
  • 21
    • 63349097919 scopus 로고    scopus 로고
    • Sustained virological response reduces incidence of onset of type 2 diabetes in chronic hepatitis C
    • Arase Y, Suzuki F, Suzuki Y, et al. Sustained virological response reduces incidence of onset of type 2 diabetes in chronic hepatitis C. Hepatology 2009; 49:739-44.
    • (2009) Hepatology , vol.49 , pp. 739-744
    • Arase, Y.1    Suzuki, F.2    Suzuki, Y.3
  • 22
    • 68249154875 scopus 로고    scopus 로고
    • Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection
    • McHutchison JG, Lawitz EJ, Shiffman ML, et al. Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection. N Engl J Med 2009; 361:580-93.
    • (2009) N Engl J Med , vol.361 , pp. 580-593
    • McHutchison, J.G.1    Lawitz, E.J.2    Shiffman, M.L.3
  • 23
    • 70349966196 scopus 로고    scopus 로고
    • Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
    • Thomas DL, Thio CL, Martin MP, et al. Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature 2009; 461:798-801.
    • (2009) Nature , vol.461 , pp. 798-801
    • Thomas, D.L.1    Thio, C.L.2    Martin, M.P.3
  • 24
    • 77949831342 scopus 로고    scopus 로고
    • Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: A genomewide association study
    • Rauch A, Kutalik Z, Descombes P, et al. Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genomewide association study. Gastroenterology 2010; 138:1338-45.
    • (2010) Gastroenterology , vol.138 , pp. 1338-1345
    • Rauch, A.1    Kutalik, Z.2    Descombes, P.3
  • 25
    • 77952693487 scopus 로고    scopus 로고
    • Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin
    • McCarthy JJ, Li JH, Thompson A, et al. Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin. Gastroenterology 2010; 138:2307-14.
    • (2010) Gastroenterology , vol.138 , pp. 2307-2314
    • McCarthy, J.J.1    Li, J.H.2    Thompson, A.3
  • 26
    • 84863528197 scopus 로고    scopus 로고
    • Will IL28B polymorphism remain relevant in the era of direct acting antiviral agents for HCV?
    • Thompson AJ, McHutchison JG. Will IL28B polymorphism remain relevant in the era of direct acting antiviral agents for HCV? Hepatology 2012; 56:383-81.
    • (2012) Hepatology , vol.56 , pp. 383-481
    • Thompson, A.J.1    McHutchison, J.G.2
  • 27
    • 79960449077 scopus 로고    scopus 로고
    • IL28b polymorphism predicts virological response in patients with chronic hepatitis C genotype 1 treated with boceprevir (BOC) combination therapy
    • Poordad F, Bronowicki JP, Gordon SC, et al. IL28b polymorphism predicts virological response in patients with chronic hepatitis C genotype 1 treated with boceprevir (BOC) combination therapy. J Hepatol 2011; 54:S12.
    • (2011) J Hepatol , vol.54
    • Poordad, F.1    Bronowicki, J.P.2    Gordon, S.C.3
  • 28
    • 79960470493 scopus 로고    scopus 로고
    • SILEN-C1: Sustained virologic response (SVR) and safety of BI201335 combined with peginterferon alfa-2a and ribavirin (P/R) in treatment-naive patients with chronic genotype 1 HCV infection
    • Sulkowski MS, Ceasu E, Asselah T, et al. SILEN-C1: Sustained virologic response (SVR) and safety of BI201335 combined with peginterferon alfa-2a and ribavirin (P/R) in treatment-naive patients with chronic genotype 1 HCV infection. J Hepatol 2011; 54(suppl 1):S27.
    • (2011) J Hepatol , vol.54 , Issue.SUPPL. 1
    • Sulkowski, M.S.1    Ceasu, E.2    Asselah, T.3
  • 29
    • 84856906043 scopus 로고    scopus 로고
    • TMC435 in combination with peginterferon and ribavirin in treatment-naive HCV genotype 1 patients: Final analysis of the PILLAR phase IIb study
    • Fried M, Buti M, Dore GJ, et al. TMC435 in combination with peginterferon and ribavirin in treatment-naive HCV genotype 1 patients: final analysis of the PILLAR phase IIb study. Hepatology 2011; 54 (suppl 1):LB5.
    • (2011) Hepatology , vol.54 , Issue.SUPPL. 1
    • Fried, M.1    Buti, M.2    Dore, G.J.3
  • 30
    • 79960720423 scopus 로고    scopus 로고
    • Telaprevir substantially improves SVR rates across all IL28B genotypes in the ADVANCE trial
    • Jacobson IM, Catlett I, Marcellin P, et al. Telaprevir substantially improves SVR rates across all IL28B genotypes in the ADVANCE trial. J Hepatol 2011; 54:S1369.
    • (2011) J Hepatol , vol.54
    • Jacobson, I.M.1    Catlett, I.2    Marcellin, P.3
  • 31
    • 83455175563 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis C GT 1 patients at an academic center in Europe involved in prospective controlled trials: Is there a selection bias?
    • Beinhardt S, Staettermayer AF, Rutter K, et al. Treatment of chronic hepatitis C GT 1 patients at an academic center in Europe involved in prospective controlled trials: is there a selection bias? Hepatology 2012; 55:30-8.
    • (2012) Hepatology , vol.55 , pp. 30-38
    • Beinhardt, S.1    Staettermayer, A.F.2    Rutter, K.3
  • 32
    • 84859412455 scopus 로고    scopus 로고
    • Effect of IL28B genotype on early viral kinetics during interferon-free treatment of patients with chronic hepatitis C
    • Chu TW, Kulkarni R, Gane EJ, et al. Effect of IL28B genotype on early viral kinetics during interferon-free treatment of patients with chronic hepatitis C. Gastroenterology 2012; 142:790-5.
    • (2012) Gastroenterology , vol.142 , pp. 790-795
    • Chu, T.W.1    Kulkarni, R.2    Gane, E.J.3
  • 33
    • 81855228070 scopus 로고    scopus 로고
    • Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection
    • Zeuzem S, Asselah T, Angus P, et al. Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection. Gastroenterology 2011; 141:2047-55.
    • (2011) Gastroenterology , vol.141 , pp. 2047-2055
    • Zeuzem, S.1    Asselah, T.2    Angus, P.3
  • 34
    • 84864367453 scopus 로고    scopus 로고
    • Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response
    • Naggie S, Anu Osinusi A, Katsounas A, et al. Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: impaired viral kinetics and therapeutic response. Hepatology 2012; 56:444-54.
    • (2012) Hepatology , vol.56 , pp. 444-454
    • Naggie, S.1    Anu Osinusi, A.2    Katsounas, A.3
  • 35
    • 1542378867 scopus 로고    scopus 로고
    • Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
    • Hadziyannis SJ, Sette H Jr, Morgan TR, et al. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004; 140:346-55.
    • (2004) Ann Intern Med , vol.140 , pp. 346-355
    • Hadziyannis, S.J.1    Sette Jr., H.2    Morgan, T.R.3
  • 36
    • 33646590308 scopus 로고    scopus 로고
    • Early identification of HCV genotype 1 patients responding to 24 weeks peginterferon α-2a (40KD)/ribavirin therapy
    • Jensen DM, Morgan TR, Marcellin P, et al. Early identification of HCV genotype 1 patients responding to 24 weeks peginterferon α-2a (40KD)/ribavirin therapy. Hepatology 2006; 43:954-60.
    • (2006) Hepatology , vol.43 , pp. 954-960
    • Jensen, D.M.1    Morgan, T.R.2    Marcellin, P.3
  • 37
    • 84857395452 scopus 로고    scopus 로고
    • Dual therapy with the NS5A inhibitor BMS-790052 and the NS3 protease inhibitor BMS-650032 in HCV genotype 1b-infected null responders
    • Chayama K, Takahashi S, Toyota J, et al. Dual therapy with the NS5A inhibitor BMS-790052 and the NS3 protease inhibitor BMS-650032 in HCV genotype 1b-infected null responders. Hepatology 2011; 55:742-8.
    • (2011) Hepatology , vol.55 , pp. 742-748
    • Chayama, K.1    Takahashi, S.2    Toyota, J.3
  • 38
    • 84856159009 scopus 로고    scopus 로고
    • Preliminary study of two antiviral agents for hepatitis C genotype 1
    • Lok AS, Gardiner DF, Lawitz E, et al. Preliminary study of two antiviral agents for hepatitis C genotype 1. N Engl J Med 2012; 366:216-24.
    • (2012) N Engl J Med , vol.366 , pp. 216-224
    • Lok, A.S.1    Gardiner, D.F.2    Lawitz, E.3
  • 39
    • 0032475822 scopus 로고    scopus 로고
    • Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy
    • Neumann AU, Lam NP, Dahari H, et al. Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy. Science 1998; 282:103-7.
    • (1998) Science , vol.282 , pp. 103-107
    • Neumann, A.U.1    Lam, N.P.2    Dahari, H.3
  • 40
    • 0030039045 scopus 로고    scopus 로고
    • Effect of interferon alfa on the dynamics of hepatitis C virus turnover in vivo
    • Zeuzem S, Schmidt JM, Lee JH, Ruster B, Roth WK. Effect of interferon alfa on the dynamics of hepatitis C virus turnover in vivo. Hepatology 1996; 23:366-71.
    • (1996) Hepatology , vol.23 , pp. 366-371
    • Zeuzem, S.1    Schmidt, J.M.2    Lee, J.H.3    Ruster, B.4    Roth, W.K.5
  • 41
    • 79957448889 scopus 로고    scopus 로고
    • Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: Implications for treatment duration
    • Guedj J, Perelson AS. Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: implications for treatment duration. Hepatology 2011; 53:1801-8.
    • (2011) Hepatology , vol.53 , pp. 1801-1808
    • Guedj, J.1    Perelson, A.S.2
  • 42
    • 79958830099 scopus 로고    scopus 로고
    • Hepatitis C virus resistance to protease inhibitors
    • Halfon P, Locarnini S. Hepatitis C virus resistance to protease inhibitors. J Hepatol 2011; 55:192-206.
    • (2011) J Hepatol , vol.55 , pp. 192-206
    • Halfon, P.1    Locarnini, S.2
  • 43
    • 0035856208 scopus 로고    scopus 로고
    • Primary interferon resistance and treatment response in chronic hepatitis C infection: A pilot study
    • Jessner W, Gschwantler M, Steindl-Munda P, et al. Primary interferon resistance and treatment response in chronic hepatitis C infection: a pilot study. Lancet 2001; 358:1241-2.
    • (2001) Lancet , vol.358 , pp. 1241-1242
    • Jessner, W.1    Gschwantler, M.2    Steindl-Munda, P.3
  • 44
    • 23444460553 scopus 로고    scopus 로고
    • Predicting sustained virological responses in chronic hepatitis C patients treated with peginterferon alfa-2a/ribavirin
    • Ferenci P, Fried MW, Shiffman ML, et al. Predicting sustained virological responses in chronic hepatitis C patients treated with peginterferon alfa-2a/ribavirin. J Hepatol 2005; 43:425-33.
    • (2005) J Hepatol , vol.43 , pp. 425-433
    • Ferenci, P.1    Fried, M.W.2    Shiffman, M.L.3
  • 45
    • 79952899824 scopus 로고    scopus 로고
    • Impact of the IL28Bgenotype on early and sustained virologic response in treatment-naive patients with chronic hepatitis C treated with peg-interferon-α2a and ribavirin
    • Stättermayer AF, Stauber R, Hofer H, et al. Impact of the IL28Bgenotype on early and sustained virologic response in treatment-naive patients with chronic hepatitis C treated with peg-interferon-α2a and ribavirin. Clin Gastroenterol Hepatol 2011; 9:344-50.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 344-350
    • Stättermayer, A.F.1    Stauber, R.2    Hofer, H.3
  • 46
    • 79958816097 scopus 로고    scopus 로고
    • Rapid virological response is the most important predictor of sustained virological response across genotypes in patients with chronic hepatitis C virus infection
    • Fried MW, Hadziyannis SJ, Shiffman ML, Messinger D, Zeuzem S. Rapid virological response is the most important predictor of sustained virological response across genotypes in patients with chronic hepatitis C virus infection. J Hepatol 2011; 55:69-75.
    • (2011) J Hepatol , vol.55 , pp. 69-75
    • Fried, M.W.1    Hadziyannis, S.J.2    Shiffman, M.L.3    Messinger, D.4    Zeuzem, S.5
  • 47
    • 48749099989 scopus 로고    scopus 로고
    • Peginterferon alfa-2a and ribavirin for 24 weeks in hepatitis C type 1 and 4 patients with rapid virological response
    • Ferenci P, Laferl H, Scherzer TM, et al. Peginterferon alfa-2a and ribavirin for 24 weeks in hepatitis C type 1 and 4 patients with rapid virological response. Gastroenterology 2008; 135:451-8.
    • (2008) Gastroenterology , vol.135 , pp. 451-458
    • Ferenci, P.1    Laferl, H.2    Scherzer, T.M.3
  • 48
    • 84855697857 scopus 로고    scopus 로고
    • Optimal treatment duration for patients with HCV genotype 1 Infection
    • Ferenci P. Optimal treatment duration for patients with HCV genotype 1 Infection. J Viral Hepat 2012; 19(suppl 1):7-13.
    • (2012) J Viral Hepat , vol.19 , Issue.SUPPL. 1 , pp. 7-13
    • Ferenci, P.1
  • 49
    • 84870018201 scopus 로고    scopus 로고
    • Recommendations for standardized nomenclature and definitions of viral response in trials of HCV investigational agents
    • on behalf of the Definitions/Nomenclature Working Group of the HCV DrAG (HCV Drug Development Advisory Group), under the auspices of the Forum for Collaborative HIV Research [Epub ahead of print] doi:10.1002/hep.2588
    • Wedemeyer H, Jensen DM, Godofsky E, et al., on behalf of the Definitions/Nomenclature Working Group of the HCV DrAG (HCV Drug Development Advisory Group), under the auspices of the Forum for Collaborative HIV Research. Recommendations for standardized nomenclature and definitions of viral response in trials of HCV investigational agents. Hepatology 2012. [Epub ahead of print]. doi:10.1002/hep.2588.
    • (2012) Hepatology
    • Wedemeyer, H.1    Jensen, D.M.2    Godofsky, E.3
  • 50
    • 0036788338 scopus 로고    scopus 로고
    • Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C
    • McHutchison JG, Manns M, Patel K, et al. Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C. Gastroenterology 2002; 123:1061-9.
    • (2002) Gastroenterology , vol.123 , pp. 1061-1069
    • McHutchison, J.G.1    Manns, M.2    Patel, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.