Pharmacokinetic and pharmacodynamic evaluation of floating microspheres of metformin hydrochloride

Drug Development and Industrial Pharmacy

Volumn 39, Issue 1, 2013, Pages 117-127

  Pandit, Vinay ^a   Pai, Roopa S ^a   Yadav, Vivek ^a   Devi, Kshama ^a   Surekha, B B ^a   Inamdar, Mohd N ^a   Suresh, Sarasija ^b  

^a AL AMEEN COLLEGE OF PHARMACY   (India)

^b NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

ANOVA; Bioavailability studies; Diabetes; Floating microspheres; OGTT; Streptozotocin

Indexed keywords

GLUCOSE; METFORMIN; MICROSPHERE; SOLVENT; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANTIDIABETIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG MECHANISM; DRUG RELEASE; DRUG STABILITY; EMULSION; EMULSION SOLVENT EVAPORATION METHOD; EVAPORATION; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PARTICLE SIZE; PHARMACODYNAMICS; POWDER X RAY DIFFRACTION; RAT; SCANNING ELECTRON MICROSCOPY; STREPTOZOCIN DIABETES; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY DIFFRACTION;

ANALYSIS OF VARIANCE; ANIMALS; BIOLOGICAL AVAILABILITY; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; MALE; METFORMIN; MICROSPHERES; PARTICLE SIZE; RATS; RATS, WISTAR;

EID: 84871215431     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2012.662503     Document Type: Article

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