메뉴 건너뛰기




Volumn 26, Issue 12, 2012, Pages 2557-2560

EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms

Author keywords

[No Author keywords available]

Indexed keywords

EMBRYONIC ECTODERM DEVELOPMENT PROTEIN; MESSENGER RNA; POLYCOMB GROUP PROTEIN; POLYCOMB RECESSIVE COMPLEX 2; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG;

EID: 84871204903     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2012.146     Document Type: Letter
Times cited : (43)

References (14)
  • 1
    • 78751662908 scopus 로고    scopus 로고
    • The polycomb complex prc2 and its mark in life
    • Margueron R, Reinberg D. The Polycomb complex PRC2 and its mark in life. Nature 2011; 469: 343-349.
    • (2011) Nature , vol.469 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2
  • 2
    • 70349469565 scopus 로고    scopus 로고
    • Mechanisms of polycomb gene silencing: Knowns and unknowns
    • Simon JA, Kingston RE. Mechanisms of polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol 2009; 10: 697-708.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 697-708
    • Simon, J.A.1    Kingston, R.E.2
  • 4
    • 77955085750 scopus 로고    scopus 로고
    • Inactivating mutations of the histone methyltransferase gene ezh2 in myeloid disorders
    • Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones AV et al. Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders. Nat Genet 2010; 42: 722-726.
    • (2010) Nat Genet , vol.42 , pp. 722-726
    • Ernst, T.1    Chase, A.J.2    Score, J.3    Hidalgo-Curtis, C.E.4    Bryant, C.5    Jones, A.V.6
  • 6
    • 0031658231 scopus 로고    scopus 로고
    • Point mutations in the WD40 domain of Eed block its interaction with Ezh2
    • Denisenko O, Shnyreva M, Suzuki H, Bomsztyk K. Point mutations in the WD40 domain of Eed block its interaction with Ezh2. Mol Cell Biol 1998; 18: 5634-5642.
    • (1998) Mol Cell Biol , vol.18 , pp. 5634-5642
    • Denisenko, O.1    Shnyreva, M.2    Suzuki, H.3    Bomsztyk, K.4
  • 7
    • 70349952171 scopus 로고    scopus 로고
    • Role of the polycomb protein EED in the propagation of repressive histone marks
    • Margueron R, Justin N, Ohno K, Sharpe ML, Son J, Drury V et al. Role of the polycomb protein EED in the propagation of repressive histone marks. Nature 2009; 461: 762-767.
    • (2009) Nature , vol.461 , pp. 762-767
    • Margueron, R.1    Justin, N.2    Ohno, K.3    Sharpe, M.L.4    Son, J.5    Drury, V.6
  • 9
    • 38349107912 scopus 로고    scopus 로고
    • Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia
    • Sauvageau M, Miller M, Lemieux S, Lessard J, Hébert J, Sauvageau G. Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia. Blood 2008; 111: 790-799.
    • (2008) Blood , vol.111 , pp. 790-799
    • Sauvageau, M.1    Miller, M.2    Lemieux, S.3    Lessard, J.4    Hébert, J.5    Sauvageau, G.6
  • 10
    • 68949124841 scopus 로고    scopus 로고
    • Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms
    • Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S et al. Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms. Nature 2009; 460: 904-908.
    • (2009) Nature , vol.460 , pp. 904-908
    • Sanada, M.1    Suzuki, T.2    Shih, L.Y.3    Otsu, M.4    Kato, M.5    Yamazaki, S.6
  • 11
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • Genomes Project Consortium.
    • Genomes Project Consortium. A map of human genome variation from population-scale sequencing. Nature 2010; 467: 1061-1073.
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 12
  • 13
    • 36248930485 scopus 로고    scopus 로고
    • Molecular and functional mapping of EED motifs required for PRC2-dependent histone methylation
    • Montgomery ND, Yee D, Montgomery SA, Magnuson T. Molecular and functional mapping of EED motifs required for PRC2-dependent histone methylation. J Mol Biol 2007; 374: 1145-1157.
    • (2007) J Mol Biol , vol.374 , pp. 1145-1157
    • Montgomery, N.D.1    Yee, D.2    Montgomery, S.A.3    Magnuson, T.4
  • 14
    • 84856596417 scopus 로고    scopus 로고
    • Inactivation of polycomb repressive complex 2 components in myeloproliferative and myelodysplasticmyeloproliferative neoplasms
    • Score J, Hidalgo-Curtis C, Jones AV, Winkelmann N, Skinner A, Ward D et al. Inactivation of polycomb repressive complex 2 components in myeloproliferative and myelodysplastic/myeloproliferative neoplasms. Blood 2011; 119: 1208-1213.
    • (2011) Blood , vol.119 , pp. 1208-1213
    • Score, J.1    Hidalgo-Curtis, C.2    Jones, A.V.3    Winkelmann, N.4    Skinner, A.5    Ward, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.