Mice deficient in ficolin, a lectin complement pathway recognition molecule, are susceptible to Streptococcus pneumoniae infection

Journal of Immunology

Volumn 189, Issue 12, 2012, Pages 5860-5866

  Endo, Yuichi ^a   Takahashi, Minoru ^a   Iwaki, Daisuke ^a   Ishida, Yumi ^a   Nakazawa, Naomi ^a   Kodama, Toshihisa ^a   Matsuzaka, Tomohiro ^a   Kanno, Kazuko ^a   Liu, Yu ^a   Tsuchiya, Kohsuke ^b   Kawamura, Ikuo ^b   Ikawa, Masahito ^c   Waguri, Satoshi ^a   Wada, Ikuo ^a   Matsushita, Misao ^d   Schwaeble, Wilhelm J ^e   Fujita, Teizo ^a  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d TOKAI UNIVERSITY   (Japan)

^e UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FICOLIN; FICOLIN A; FICOLIN B; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; BACTERIAL STRAIN; COMPLEMENT ACTIVATION; COMPLEMENT LECTIN PATHWAY; COMPLEX FORMATION; FEMALE; HOST RESISTANCE; IN VIVO STUDY; INFECTION SENSITIVITY; INNATE IMMUNITY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STREPTOCOCCUS PNEUMONIAE; SURVIVAL RATE; WILD TYPE;

ANIMALS; CHO CELLS; COMPLEMENT ACTIVATION; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; CRICETINAE; GENETIC PREDISPOSITION TO DISEASE; LECTINS; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PNEUMONIA, PNEUMOCOCCAL; STREPTOCOCCUS PNEUMONIAE;

EID: 84871165182     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200836     Document Type: Article

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