Pathways related to mitochondrial dysfunction in cartilage of endemic osteoarthritis patients in China

Science China Life Sciences

Volumn 55, Issue 12, 2012, Pages 1057-1063

  Li, ChunYan ^a,b   Wang, WeiZhuo ^c   Guo, Xiong ^a   Zhang, Feng ^a   Ma, WeiJuan ^a   Zhang, YinGang ^c   Li, YouFen ^c   Bai, YiDong ^d   Lammi, Mikko J ^e  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b Institute of Health Education of Xi'an   (China)

^c XI'AN JIAOTONG UNIVERSITY   (China)

^d University of Texas Health Science Center   (United States)

^e UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

IPA analysis; Kashin Beck disease; microarray; mitochondrial dysfunction

Indexed keywords

ADULT; APOPTOSIS; ARTICLE; CARTILAGE; CASE CONTROL STUDY; CHINA; DNA MICROARRAY; ENDEMIC DISEASE; FEMALE; GENE EXPRESSION PROFILING; GENETICS; HUMAN; KASHIN BECK DISEASE; MALE; METABOLISM; MIDDLE AGED; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; APOPTOSIS; CARTILAGE; CASE-CONTROL STUDIES; CHINA; ENDEMIC DISEASES; FEMALE; GENE EXPRESSION PROFILING; HUMANS; KASHIN-BECK DISEASE; MALE; MIDDLE AGED; MITOCHONDRIA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE PHOSPHORYLATION;

EID: 84871159579     PISSN: 16747305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11427-012-4418-4     Document Type: Article

References (28)

1. Duan C, Guo X, Zhang X D, et al. Comparative analysis of gene expression profiles between primary knee osteoarthritis and an osteoarthritis endemic to northwestern china, kashin-beck disease. Arthritis Rheum, 2010, 62: 771-780.
2. Downey C M, Horton C R, Carlson B A, et al. Osteo-chondroprogenitor-specific deletion of the selenocysteine trna gene, trsp, leads to chondronecrosis and abnormal skeletal development: A putative model for kashin-beck disease. PLoS Genet, 2009, 5: e1000616.
3. Moreno-Reyes R, Suetens C, Mathieu F, et al. Kashin-beck osteoarthropathy in rural tibet in relation to selenium and iodine status. N Engl J Med, 1998, 339: 1112-1120.
4. Guo X, Zuo H, Cao C X, et al. Abnormal expression of col x, pthrp, tgf-beta, bfgf, and vegf in cartilage with kashin-beck disease. J Bone Miner Metab, 2006, 24: 319-328.
5. Wang S J, Guo X, Zuo H, et al. Chondrocyte apoptosis and expression of bcl-2, bax, fas, and inos in articular cartilage in patients with kashin-beck disease. J Rheumatol, 2006, 33: 615-619.
6. Liu J T, Guo X, Ma W J, et al. Mitochondrial function is altered in articular chondrocytes of an endemic osteoarthritis, kashin-beck disease. Osteoarthritis Cartilage, 2010, 18: 1218-1226.
7. Wang W Z, Guo X, Duan C, et al. Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis. Osteoarthritis Cartilage, 2009, 17: 83-90.
8. Shi T, Mazumdar T, Devecchio J, et al. Cdna microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. PLoS One, 2010, 5: e13054.
9. Mehta R G, Whyte L, Huang Y Y, et al. Molecular mechanisms of resveratrol action in lung cancer cells using dual protein and microarray analyses. Cancer Res, 2007, 67: 12007-12017.
10. Andrews J, Kennette W, Pilon J, et al. Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number. PLoS One, 2010, 5: e8665.
11. Lee H M, Sugino H, Aoki C, et al. Abnormal networks of immune response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysis. Arthritis Res Ther, 2011, 13: R89.
12. Bai X, Wu J, Zhang Q, et al. Third-generation human mitochondria-focused cdna microarray and its bioinformatic tools for analysis of gene expression. Biotechniques, 2007, 42: 365-375.
13. Green D R, Reed J C. Mitochondria and apoptosis. Science, 1998, 281: 1309-1312.
14. Chittenden T, Flemington C, Houghton A B, et al. A conserved domain in bak, distinct from bh1 and bh2, mediates cell death and protein binding functions. EMBO J, 1995, 14: 5589-5596.
15. Jurgensmeier J M, Xie Z, Deveraux Q, et al. Bax directly induces release of cytochrome c from isolated mitochondria. Proc Natl Acad Sci USA, 1998, 95: 4997-5002.
16. Malladi S, Challa-Malladi M, Fearnhead H O, et al. The apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer. EMBO J, 2009, 28: 1916-1925.
17. Zou H, Li Y, Liu X, et al. An apaf-1. Cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem, 1999, 274: 11549-11556.
18. Robertus J D, Suh J K, Poulsen L L, et al. Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum. Proc Natl Acad Sci USA, 1999, 96: 2687-2691.
19. Xiong Y M, Mo X Y, Zou X Z, et al. Association study between polymorphisms in selenoprotein genes and susceptibility to kashin-beck disease. Osteoarthritis Cartilage, 2010, 18: 817-824.
20. Sugden M C, Holness M J. Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by pdks. Am J Physiol-Endoc M, 2003, 284: E855-E862.
21. Hatefi Y. The mitochondrial electron-transport and oxidative-phosphorylation system. Annu Rev Biochem, 1985, 54: 1015-1069.
22. Butow R A, Epstein C B, Waddle J A, et al. Genome-wide responses to mitochondrial dysfunction. Mol Biol Cell, 2001, 12: 297-308.
23. Cortopassi G A, Wong A. Mitochondria in organismal aging and degeneration. Bba-Bioenergetics, 1999, 1410: 183-193.
24. Wallace D C. Mitochondrial diseases in man and mouse. Science, 1999, 283: 1482-1488.
25. Brenner C, Kroemer G. Apoptosis. Mitochondria-the death signal integrators. Science, 2000, 289: 1150-1151.
26. Hawkes W C, Alkan Z. Regulation of redox signaling by selenoproteins. Biol Trace Elem Res, 2010, 134: 235-251.
27. Gibson B W. The human mitochondrial proteome: oxidative stress, protein modifications and oxidative phosphorylation. Int J Biochem Cell B, 2005, 37: 927-934.
28. Shokolenko I, Venediktova N, Bochkareva A, et al. Oxidative stress induces degradation of mitochondrial DNA. Nucleic Acids Res, 2009, 37: 2539-2548.