Association study between polymorphisms in selenoprotein genes and susceptibility to Kashin-Beck disease

Osteoarthritis and Cartilage

Volumn 18, Issue 6, 2010, Pages 817-824

  Xiong, Y M ^a,b   Mo, X Y ^a   Zou, X Z ^b   Song, R X ^b   Sun, W Y ^b   Lu, W ^a   Chen, Q ^b   Yu, Y X ^c   Zang, W J ^a,b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^c Shaanxi Provincial Institute for Endemic Disease Control   (China)

Author keywords

Disease susceptibility; Genetic polymorphism; Kashin Beck disease; Selenoprotein

Indexed keywords

GLUTATHIONE PEROXIDASE 1; LEUCINE; MESSENGER RNA; PROLINE; PROTEIN P53; SELENOPROTEIN; SELENOPROTEIN P; THIOREDOXIN REDUCTASE 2; THYROXINE DEIODINASE; TRANSCRIPTION FACTOR RELA;

ADULT; ARTICLE; ARTICULAR CARTILAGE; CHINESE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HIGH RISK POPULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; OSTEOARTHROPATHY; PATHOGENESIS; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE PEROXIDASE; HUMANS; MALE; MIDDLE AGED; NF-KAPPA B; OSTEOARTHRITIS; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, MESSENGER; SELENOPROTEINS; TRANSCRIPTION FACTOR RELA;

EID: 77952882390     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2010.02.004     Document Type: Article

References (41)

1. Yang J.B. Research report on the etiology of Kashin-Beck disease (KBD). Chin J Endemiol 1995, 14(4):201-204.
2. Allander E. Kashin-Beck disease. An analysis of research and public health activities based on a bibliography 1849-1992. Scand J Rheumatol 1994, 23(99):1-36.
3. Guo X. Molecular biological mechanism on chondronecrosis in cartilage with KashineBeck disease. J Xi'an Jiaotong Univ Med Sci 2005, 26(3):201-204.
4. Wang S.J., Guo X., Zuo H., Zhang Y.G., Xu P., Ping Z.G., et al. Chondrocyte apoptosis and expression of Bcl-2, Bax, Fas, and iNOS in articular cartilage in patients with Kashine Beck disease. J Rheumatol 2006, 33:615-619.
5. Chen Y., Zhai J.M., Wang Z.L., Tan X.W., Xue L., Geng D. A comparative research on the treatment effect of Se supplement, Vit C supplement and cereals dryness on Kashin-Beck disease. Chin J Ctrl Endem Dis 2003, 18(6):343-346.
6. Wang Z.L. Synchronous study on the four kinds of etiological hypotheses of Kashin-Beck Disease. J Xi'an Jiaotong Univ Med Sci 2005, 26(1):1-7.
7. Moreno-Reyes R., Mathieu F., Boelaert M., Begaux F., Suetens C., Rivera M.T., et al. Selenium and iodine supplementation of rural Tibetan children affected by Kashin-Beck osteoarthropathy. Am J Clin Nutr 2003, 78(1):137-144.
8. Shi X.W., Guo X., Ren F.L., Lu A.L., Zhang Y.Z. Familial aggregation and sibling heritability in Kashin-Beck disease. J South Med Univ 2008, 28(7):1187-1194.
9. Gromer S., Eubel J.K., Lee B.L., Jacob J. Human selenoproteins at a glance. Cell Mol Life Sci. 2005, 62(21):2414-2437.
10. Downey C.M., Horton C.R., Carlson B.A., Parsons T.E., Hatfield D.L., Hallgrímsson B., et al. Osteo-chondroprogenitor-specific deletion of the selenocysteine tRNA gene, Trsp, leads to chondronecrosis and abnormal skeletal development: a putative model for Kashin-Beck disease. PLoS Genet 2009, 5(8):e1000616.
11. Ebert R., Jakob F. Selenium deficiency as a putative risk factor for osteoporosis. Int Congr Ser 2007, 1297:158-164.
12. Cebrian A., Pharoah P.D., Ahmed S., Smith P.L., Luccarini C., Luben R., et al. Polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer. Cancer Res 2006, 66(2):1225-1233.
13. Bianco A.C., Salvatore D., Gereben B., Berry M.J., Larsen P.R. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev 2002, 23(1):38-89.
14. Brigelius-Flohe R. Selenium compounds and selenoproteins in cancer. Chem. Biol. 2008, 5:389-395.
15. Wang W.Z., Guo X., Duan C., Ma W.J., Zhang Y.G., Xu P., et al. Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis. Osteoarthritis Cartilage 2009, 17:83-90.
16. Kuzuya M., Ando F., Iguchi A., Shimokata H. Glutathione peroxidase 1 Pro198Leu variant contributes to the metabolic syndrome in men in a large Japanese cohort. Am J Clin Nutr 2008, 87:1939-1944.
17. De Jong F.J., Peeters R.P., Heijer T.D., Van der Deure W.M., Hofman A., Uitterlinden A.G., et al. The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe. J Clin Endocrinol Metab 2007, 92(2):636-640.
18. Knight J.A., Onay U.V., Wells S., Li H., Shi E.J.Q., Andrulis I.L., et al. Genetic variants of GPX1 and SOD2 and breast cancer risk at the Ontario site of the breast cancer family registry cancer epidemiology, biomarkers & prevention cancer epidemiology. Biomarkers Prev 2004, 13:146-149.
19. Peters U., Chatterjee N., Hayes R.B., Schoen R.E., Wang Y.H., Chanock S.J., et al. Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. Cancer Epidemiol Biomarkers Prev 2008, 17(5):1144-1154.
20. Guo X., Zhang S.Y., Mo D.X. The Role of low selenium in the occurrence of Kashin-Beck Disease. Xi'an Med Univ 1992, 4(2):99-106.
21. Wang H.Y., Chen Z. The paired study on the relationship between KBD and Selenium in hair. Chin J Ctrl Endem Dis 2008, 23(1):59-60.
22. Xiong Y.M., Bi H.Y., Wang Z.L., Bai S., Yu Z.D., Xue L., et al. Determination of blood selenium, vitamin C and phosphorus in people from the co-existence of KBD and KSD areas and some special areas. GUANGDONG TRACE ELEMENTS SCIENCE 1998, 5(10):18-21.
23. Hashimoto T., Hashimoto K., Miyatake R., Matsuzawa D., Sekine Y., Inada T., et al. Association study between polymorphisms in glutathione-related genes and methamphetamine use disorder in a Japanese population. Am J Med Genet B 2008, 147B:1040-1046.
24. Tang N.P., Wang L.S., Yang L., Gu H.J., Sun Q.M., Cong R.H., et al. Genetic variant in glutathione peroxidase 1 gene is associated with an increased risk of coronary artery disease in a Chinese population. Clin Chim Acta 2008, 395:89-93.
25. Me C., Crosley L.K., Nicol F., Beckett G.J., Howie A.F., Hill K.E., et al. Genetic polymorphisms in the human selenoprotein P gene determine the response of selenoprotein markers to selenium supplementation in a genderspecific manner (the SELGEN study). The FASEB J 2007, 21:3063-3074.
26. Meulenbelt I., Min J.L., Bos S., Riyazi N., Houwing-Duistermaat J.J., van der Wijk H.J., et al. Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis. Hum Mol Genet 2008, 17(12):1867-1875.
27. Rotruck J.T., Pope A.L., Ganther H.E., Swanson A.B., Hafeman D.G., Hoekstra W.G. Selenium: biochemical role as a component of glutathione peroxidase. Science 1973, 179:588-590.
28. Jablonska E., Gromadzinska J., Reszka E., Wasowicz W., Sobala W., Szeszenia-Dabrowska N., et al. Association between GPx1 Pro198Leu polymorphism, GPx1 activity and plasma selenium concentration in humans. Eur J Nutr 2009, 48:383-386.
29. Ratnasinghe D., Tangrea J.A., Andersen M.R., Barrett M.J., Virtamo J., Taylor P.R., et al. Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk. Cancer Res 2000, 60:6381-6383.
30. Hu Y.J., Diamond A.M. Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium. Cancer Res 2003, 63:3347-3351.
31. Raaschou-Nielsen O., Sorensen M., Hansen R.D., Frederiksen K., Tjonneland A., Overvad K., et al. GPX1 Pro198Leu polymorphism, interactions with smoking and alcohol consumption, and risk for lung cancer. Cancer Lett 2007, 247:293-300.
32. Ravn-Haren G., Olsen A., Tjonneland A., Dragsted L.O., Nexo B.A., Wallin H., et al. Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study. Carcinogenesis 2006, 27:820-825.
33. Hu Y., Benya R.V., Carroll R.E., Diamond A.M. Allelic loss of the gene for the GPX1 selenium-containing protein is a common event in cancer. J Nutr 2005, 135(Suppl):3021S-3024S.
34. Ahn J., Gammon M.D., Santella R.M., Gaudet M.M., Britton J.A., Teitelbaum S.L., et al. No association between glutathione peroxidase Pro198Leu polymorphism and breast cancer risk. Cancer Epidemiol Biomarkers Prev 2005, 14(10):2459-2461.
35. Foster C.B., Aswath K., Chanock S.J., McKay H.F., Peters U. Polymorphism analysis of six selenoprotein genes: support for a selective sweep at the glutathione peroxidase 1 locus (3p21) in Asian populations. BMC Genet 2006, 7:56-75.
36. Cheng W.H., Ho Y.S., Valentine B.A., Ross D.A., Combs G.F., Lei X.G., et al. Cellular glutathione peroxidase is the mediator of body selenium to protect against paraquat lethality in transgenic mice. J Nutr 1998, 128:1070-1076.
37. Zhang B.D., Guo X., Bai G.L., Ping Z.G., Zuo H., Ren F.L., et al. The changes of nitric oxide, No synthase and sFas/APo-1 in serum among the patients with Kashin Beck disease. Chin J Endemiol 2004, 23(2):172-175.
38. Wang S.J., Guo X., Zhang Z.T., Guo R., Chen J.H., Ren F.L., et al. The apoptotic chondrocytes in articular cartilage of children and adults with Kashin-Beck disease. J Xi'an Jiaotong Univ Med Sci 2006, 27(6):561-565.
39. Sousa L.P., Carmo A.F., Rezende B.M., Lopes F., Silva D.M., Alessandri A.L., et al. Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-kappaB. Biochem Pharmacol 2009, 78(4):396-405.
40. Janardhanan R., Banik Naren L., Ray S.K. N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53. Biochem Pharmacol 2009, 78:1105-1114.
41. Jeong S.J., Radonovich M., Brady J.N., Pise-Masison C.A. HTLV-I tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity. Blood 2004, 104:1490-1497.