Neuron-restrictive silencer factor (NRSF) represses cocaine- and amphetamine-regulated transcript (CART) transcription and antagonizes cAMP-response element-binding protein signaling through a dual NRSE mechanism

Journal of Biological Chemistry

Volumn 287, Issue 51, 2012, Pages 42574-42587

  Zhang, Jing ^a   Wang, Sihan ^a   Yuan, Lin ^b   Yang, Yinxiang ^a   Zhang, Bowen ^a   Liu, Qingbin ^a   Chen, Lin ^a   Yue, Wen ^a   Li, Yanhua ^a   Pei, Xuetao ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN INJURY; CAMP-RESPONSE ELEMENT-BINDING PROTEINS; COREPRESSORS; FORSKOLIN; IN-VITRO; MRNA LEVEL; NEURON-RESTRICTIVE SILENCER FACTORS; NEURONAL SURVIVAL; NEUROPROTECTION; OVER-EXPRESSION; REGULATORY MECHANISM; REPORTER GENE ASSAYS; THERAPEUTIC TARGETS; TRANSCRIPTIONAL REPRESSORS; UP-REGULATION;

CELL DEATH; GLUCOSE; NEURONS; PROTEINS;

TRANSCRIPTION;

COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FORSKOLIN; HISTONE DEACETYLASE 1; MESSENGER RNA; NEURON RESTRICTIVE SILENCER FACTOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT GENE; CONTROLLED STUDY; GENE; GENE ACTIVATION; GENE FUNCTION; GENE IDENTIFICATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRON; NERVE CELL; NERVE CELL NECROSIS; NEURON RESTRICTIVE SILENCER FACTOR GENE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION TERMINATION; UPREGULATION;

BASE SEQUENCE; CELL DEATH; CELL HYPOXIA; CELL SURVIVAL; CO-REPRESSOR PROTEINS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FORSKOLIN; GLUCOSE; HELA CELLS; HUMANS; INTRONS; ISCHEMIA; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84871124635     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.376590     Document Type: Article

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