Human exonuclease 5 is a novel sliding exonuclease required for genome stability

Journal of Biological Chemistry

Volumn 287, Issue 51, 2012, Pages 42773-42783

  Sparks, Justin L ^a   Kumar, Rakesh ^b   Singhs, Mayank ^b   Wold, Marc S ^c   Pandita, Tej K ^b   Burgers, Peter M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DAMAGES; DNA DAMAGING AGENTS; DNA REPLICATION FORKS; EXONUCLEASE; GENOME STABILITY; HUMAN CELLS; HUMAN REPLICATION PROTEIN A (HRPA); IRON-SULFUR CLUSTERS; MITOCHONDRIAL GENOMES; NUCLEAR DNA; SINGLE-STRANDED BINDINGS; SINGLE-STRANDED DNA;

GENES; LOADING; PROTEINS; SULFUR; YEAST;

DNA;

EXODEOXYRIBONUCLEASE V; REPLICATION FACTOR A; SINGLE STRANDED DNA;

ARTICLE; BINDING AFFINITY; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; GENETIC ANALYSIS; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; MOLECULAR PATHOLOGY; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DNA BINDING; PROTEIN FUNCTION; SPECIES DIFFERENCE;

AMINO ACID SEQUENCE; BIOCATALYSIS; CHROMOSOME ABERRATIONS; CONSERVED SEQUENCE; CROSS-LINKING REAGENTS; DNA REPAIR; DNA, SINGLE-STRANDED; EXONUCLEASES; GENOME, HUMAN; GENOMIC INSTABILITY; HUMANS; IRON-SULFUR PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN MULTIMERIZATION; REPLICATION PROTEIN A; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; ULTRAVIOLET RAYS;

SACCHAROMYCES CEREVISIAE;

EID: 84871105537     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.422444     Document Type: Article

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