Transcripts of a heterologous gene encoding mite allergen der f 7 are stabilized by codon optimization in Aspergillus oryzae

Applied Microbiology and Biotechnology

Volumn 96, Issue 5, 2012, Pages 1275-1282

  Tanaka, Mizuki ^a   Tokuoka, Masafumi ^a,b   Shintani, Takahiro ^a   Gomi, Katsuya ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b NATIONAL RESEARCH INSTITUTE OF BREWING   (Japan)

Author keywords

1,10 Phenanthroline; Aspergillus oryzae; Codon optimization; Heterologous gene expression; mRNA stability; Nonstop mRNA decay

Indexed keywords

1 ,10-PHENANTHROLINE; ASPERGILLUS ORYZAE; CODON OPTIMIZATION; HETEROLOGOUS GENES; MRNA STABILITY; NONSTOP MRNA DECAY;

ALLERGIES; ASPERGILLUS; GENE ENCODING; TRANSCRIPTION;

OPTIMIZATION;

1,10 PHENANTHROLINE; COMPLEMENTARY DNA; DER F 7 ALLERGEN; GLUCAN 1,4 ALPHA GLUCOSIDASE; HOUSE DUST ALLERGEN; MESSENGER RNA; UNCLASSIFIED DRUG;

AMINO ACID; FUNGUS; GENE EXPRESSION; INHIBITOR; MITE; OPTIMIZATION; PROTEIN;

ARTICLE; ASPERGILLUS ORYZAE; CODON; CODON OPTIMIZATION; CONTROLLED STUDY; FUNGAL GENE; GENE FUSION; GENETIC CODE; GENETIC STABILITY; HALF LIFE TIME; MESSENGER RNA SYNTHESIS; NONHUMAN; POLYADENYLATION; PROTEIN DEGRADATION; RNA STABILITY; TRANSCRIPTION REGULATION;

ANIMALS; ANTIGENS, DERMATOPHAGOIDES; ARTHROPOD PROTEINS; ASPERGILLUS ORYZAE; CODON; DERMATOPHAGOIDES FARINAE; GENE EXPRESSION PROFILING; RECOMBINANT PROTEINS; RNA STABILITY; TRANSCRIPTION, GENETIC;

ACARI; ASPERGILLUS ORYZAE; DERMATOPHAGOIDES FARINAE; EUKARYOTA;

EID: 84871069053     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4169-y     Document Type: Article

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