Investigating the binding interactions of galantamine with β-amyloid peptide

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 1, 2013, Pages 239-243

  Rao, Praveen P N ^a   Mohamed, Tarek ^a   Osman, Wesseem ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

Author keywords

Amyloid peptide (A ); Acetylcholinesterase (AChE); Alzheimer's disease (AD); Butyrylcholinesterase (BuChE); Cholinesterase inhibitors (ChEIs); Disease modifying agents (DMA); Molecular dynamics (MD); Nuclear magnetic resonance (NMR); Root mean square deviation (RMSD)

Indexed keywords

AMYLOID BETA PROTEIN; AZEPINE DERIVATIVE; DIMER; DONEPEZIL; GALANTAMINE; NITROGEN; OLIGOMER; RIVASTIGMINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CHEMICAL INTERACTION; CONFORMATION; CONFORMATIONAL TRANSITION; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; OLIGOMERIZATION; SIMULATION;

AMYLOID BETA-PEPTIDES; BINDING SITES; DIMERIZATION; GALANTAMINE; MOLECULAR DOCKING SIMULATION; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS;

EID: 84871005647     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.10.111     Document Type: Article

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