메뉴 건너뛰기




Volumn 19, Issue 2, 2013, Pages 153-161

Accumulation of cortical hyperphosphorylated neurofilaments as a marker of neurodegeneration in multiple sclerosis

Author keywords

demyelinated cortex; Hyperphosphorylated; neurodegeneration; neurofilament

Indexed keywords

BIOLOGICAL MARKER; NEUROFILAMENT H PROTEIN; NEUROFILAMENT PROTEIN; UNCLASSIFIED DRUG;

EID: 84870999501     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458512451661     Document Type: Article
Times cited : (24)

References (36)
  • 1
    • 0034026912 scopus 로고    scopus 로고
    • Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation
    • Bitsch A, Schuchardt J, Bunkowski S, et al. Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation. Brain. 2000 ; 123 (Pt 6). 1174-1183
    • (2000) Brain , vol.123 , Issue.PART 6 , pp. 1174-1183
    • Bitsch, A.1    Schuchardt, J.2    Bunkowski, S.3
  • 2
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B, Matyszak MK, et al. Axonal damage in acute multiple sclerosis lesions. Brain. 1997 ; 120 (Pt 3). 393-399
    • (1997) Brain , vol.120 , Issue.PART 3 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2
  • 3
    • 66549130329 scopus 로고    scopus 로고
    • The relation between inflammation and neurodegeneration in multiple sclerosis brains
    • Frischer JM, Bramow S, Dal-Bianco A, et al. The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain. 2009 ; 132: 1175-1189
    • (2009) Brain , vol.132 , pp. 1175-1189
    • Frischer, J.M.1    Bramow, S.2    Dal-Bianco, A.3
  • 4
    • 72949097024 scopus 로고    scopus 로고
    • Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord
    • Schirmer L, Albert M, Buss A, et al. Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord. Ann Neurol. 2009 ; 66: 698-704
    • (2009) Ann Neurol , vol.66 , pp. 698-704
    • Schirmer, L.1    Albert, M.2    Buss, A.3
  • 5
    • 77950862182 scopus 로고    scopus 로고
    • Multiple sclerosis - Candidate mechanisms underlying CNS atrophy
    • Siffrin V, Vogt J, Radbruch H, et al. Multiple sclerosis - candidate mechanisms underlying CNS atrophy. Trends Neurosci. 2010 ; 33: 202-210
    • (2010) Trends Neurosci , vol.33 , pp. 202-210
    • Siffrin, V.1    Vogt, J.2    Radbruch, H.3
  • 6
    • 0032576752 scopus 로고    scopus 로고
    • Axonal transection in the lesions of multiple sclerosis
    • Trapp BD, Peterson J, Ransohoff RM, et al. Axonal transection in the lesions of multiple sclerosis. N Engl J Med. 1998 ; 338: 278-285
    • (1998) N Engl J Med , vol.338 , pp. 278-285
    • Trapp, B.D.1    Peterson, J.2    Ransohoff, R.M.3
  • 7
    • 0036830526 scopus 로고    scopus 로고
    • Thalamic neurodegeneration in multiple sclerosis
    • Cifelli A, Arridge M, Jezzard P, et al. Thalamic neurodegeneration in multiple sclerosis. Ann Neurol. 2002 ; 52: 650-653
    • (2002) Ann Neurol , vol.52 , pp. 650-653
    • Cifelli, A.1    Arridge, M.2    Jezzard, P.3
  • 8
    • 67749146330 scopus 로고    scopus 로고
    • Spinal cord neuronal pathology in multiple sclerosis
    • Gilmore CP, DeLuca GC, Bo L, et al. Spinal cord neuronal pathology in multiple sclerosis. Brain Pathol. 2009 ; 19: 642-649
    • (2009) Brain Pathol , vol.19 , pp. 642-649
    • Gilmore, C.P.1    Deluca, G.C.2    Bo, L.3
  • 9
    • 61649099869 scopus 로고    scopus 로고
    • Substantial archaeocortical atrophy and neuronal loss in multiple sclerosis
    • Papadopoulos D, Dukes S, Patel R, et al. Substantial archaeocortical atrophy and neuronal loss in multiple sclerosis. Brain Pathol. 2009 ; 19: 238-253
    • (2009) Brain Pathol , vol.19 , pp. 238-253
    • Papadopoulos, D.1    Dukes, S.2    Patel, R.3
  • 11
    • 70350044493 scopus 로고    scopus 로고
    • Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis
    • Vogt J, Paul F, Aktas O, et al. Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis. Ann Neurol. 2009 ; 66: 310-322
    • (2009) Ann Neurol , vol.66 , pp. 310-322
    • Vogt, J.1    Paul, F.2    Aktas, O.3
  • 12
    • 33748997359 scopus 로고    scopus 로고
    • Neocortical neuronal, synaptic, and glial loss in multiple sclerosis
    • Wegner C, Esiri MM, Chance SA, et al. Neocortical neuronal, synaptic, and glial loss in multiple sclerosis. Neurology. 2006 ; 67: 960-967
    • (2006) Neurology , vol.67 , pp. 960-967
    • Wegner, C.1    Esiri, M.M.2    Chance, S.A.3
  • 13
    • 0348011603 scopus 로고    scopus 로고
    • Functions of intermediate filaments in neuronal development and disease
    • Lariviere RC, Julien JP. Functions of intermediate filaments in neuronal development and disease. J Neurobiol. 2004 ; 58: 131-148
    • (2004) J Neurobiol , vol.58 , pp. 131-148
    • Lariviere, R.C.1    Julien, J.P.2
  • 14
    • 0142026833 scopus 로고    scopus 로고
    • Does neurofilament phosphorylation regulate axonal transport?
    • Shea TB, Jung C, Pant HC. Does neurofilament phosphorylation regulate axonal transport?. Trends Neurosci. 2003 ; 26: 397-400
    • (2003) Trends Neurosci , vol.26 , pp. 397-400
    • Shea, T.B.1    Jung, C.2    Pant, H.C.3
  • 15
    • 0002918293 scopus 로고
    • Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ
    • Sternberger LA, Sternberger NH. Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ. Proc Natl Acad Sci U S A. 1983 ; 80: 6126-6130
    • (1983) Proc Natl Acad Sci U S A , vol.80 , pp. 6126-6130
    • Sternberger, L.A.1    Sternberger, N.H.2
  • 17
    • 51349115914 scopus 로고    scopus 로고
    • Phosphorylation and compactness of neurofilaments in multiple sclerosis: Indicators of axonal pathology
    • Petzold A, Gveric D, Groves M, et al. Phosphorylation and compactness of neurofilaments in multiple sclerosis: indicators of axonal pathology. Exp Neurol. 2008 ; 213: 326-335
    • (2008) Exp Neurol , vol.213 , pp. 326-335
    • Petzold, A.1    Gveric, D.2    Groves, M.3
  • 18
    • 15944409728 scopus 로고    scopus 로고
    • Neurofilament phosphoforms: Surrogate markers for axonal injury, degeneration and loss
    • Petzold A. Neurofilament phosphoforms: surrogate markers for axonal injury, degeneration and loss. J Neurol Sci. 2005 ; 233: 183-198
    • (2005) J Neurol Sci , vol.233 , pp. 183-198
    • Petzold, A.1
  • 20
    • 0028352092 scopus 로고
    • Characterization of a shared epitope in cortical Lewy body fibrils and Alzheimer paired helical filaments
    • Pollanen MS, Bergeron C, Weyer L. Characterization of a shared epitope in cortical Lewy body fibrils and Alzheimer paired helical filaments. Acta Neuropathol. 1994 ; 88: 1-6
    • (1994) Acta Neuropathol , vol.88 , pp. 1-6
    • Pollanen, M.S.1    Bergeron, C.2    Weyer, L.3
  • 21
    • 0023707216 scopus 로고
    • Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis
    • Manetto V, Sternberger NH, Perry G, et al. Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol. 1988 ; 47: 642-653
    • (1988) J Neuropathol Exp Neurol , vol.47 , pp. 642-653
    • Manetto, V.1    Sternberger, N.H.2    Perry, G.3
  • 22
    • 0034842126 scopus 로고    scopus 로고
    • Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
    • Peterson JW, Bo L, Mork S, et al. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol. 2001 ; 50: 389-400
    • (2001) Ann Neurol , vol.50 , pp. 389-400
    • Peterson, J.W.1    Bo, L.2    Mork, S.3
  • 23
    • 70149124713 scopus 로고    scopus 로고
    • Demyelination, inflammation, and neurodegeneration in multiple sclerosis deep gray matter
    • Vercellino M, Masera S, Lorenzatti M, et al. Demyelination, inflammation, and neurodegeneration in multiple sclerosis deep gray matter. J Neuropathol Exp Neurol. 2009 ; 68: 489-502
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 489-502
    • Vercellino, M.1    Masera, S.2    Lorenzatti, M.3
  • 24
    • 34548297818 scopus 로고    scopus 로고
    • Altered glutamate reuptake in relapsing-remitting and secondary progressive multiple sclerosis cortex: Correlation with microglia infiltration, demyelination, and neuronal and synaptic damage
    • Vercellino M, Merola A, Piacentino C, et al. Altered glutamate reuptake in relapsing-remitting and secondary progressive multiple sclerosis cortex: correlation with microglia infiltration, demyelination, and neuronal and synaptic damage. J Neuropathol Exp Neurol. 2007 ; 66: 732-739
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 732-739
    • Vercellino, M.1    Merola, A.2    Piacentino, C.3
  • 25
    • 0022643225 scopus 로고
    • Phosphorylated neurofilament antigens in neurofibrillary tangles in Alzheimer's disease
    • Cork LC, Sternberger NH, Sternberger LA, et al. Phosphorylated neurofilament antigens in neurofibrillary tangles in Alzheimer's disease. J Neuropathol Exp Neurol. 1986 ; 45: 56-64
    • (1986) J Neuropathol Exp Neurol , vol.45 , pp. 56-64
    • Cork, L.C.1    Sternberger, N.H.2    Sternberger, L.A.3
  • 26
    • 0022635673 scopus 로고
    • Reaction of Lewy bodies with antibodies to phosphorylated and non-phosphorylated neurofilaments
    • Forno LS, Sternberger LA, Sternberger NH, et al. Reaction of Lewy bodies with antibodies to phosphorylated and non-phosphorylated neurofilaments. Neurosci Lett. 1986 ; 64: 253-258
    • (1986) Neurosci Lett , vol.64 , pp. 253-258
    • Forno, L.S.1    Sternberger, L.A.2    Sternberger, N.H.3
  • 27
    • 0023738527 scopus 로고
    • Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients
    • Munoz DG, Greene C, et al. Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients. J Neuropathol Exp Neurol. 1988 ; 47: 9-18
    • (1988) J Neuropathol Exp Neurol , vol.47 , pp. 9-18
    • Munoz, D.G.1    Greene, C.2
  • 28
    • 0025165101 scopus 로고
    • Phosphorylated high molecular weight neurofilament protein in lower motor neurons in amyotrophic lateral sclerosis and other neurodegenerative diseases involving ventral horn cells
    • Sobue G, Hashizume Y, Yasuda T, et al. Phosphorylated high molecular weight neurofilament protein in lower motor neurons in amyotrophic lateral sclerosis and other neurodegenerative diseases involving ventral horn cells. Acta Neuropathol. 1990 ; 79: 402-408
    • (1990) Acta Neuropathol , vol.79 , pp. 402-408
    • Sobue, G.1    Hashizume, Y.2    Yasuda, T.3
  • 30
    • 12444288619 scopus 로고    scopus 로고
    • Axonal damage accumulates in the progressive phase of multiple sclerosis: Three year follow up study
    • Petzold A, Eikelenboom MJ, Keir G, et al. Axonal damage accumulates in the progressive phase of multiple sclerosis: three year follow up study. J Neurol Neurosurg Psychiatry. 2005 ; 76: 206-211
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 206-211
    • Petzold, A.1    Eikelenboom, M.J.2    Keir, G.3
  • 31
    • 79958838939 scopus 로고    scopus 로고
    • Axonal loss and neurofilament phosphorylation changes accompany lesion development and clinical progression in multiple sclerosis
    • Schirmer L, Antel JP, et al. Axonal loss and neurofilament phosphorylation changes accompany lesion development and clinical progression in multiple sclerosis. Brain Pathol. 2011 ; 21: 428-440
    • (2011) Brain Pathol , vol.21 , pp. 428-440
    • Schirmer, L.1    Antel, J.P.2
  • 32
    • 80055010862 scopus 로고    scopus 로고
    • Axonal damage in the making: Neurofilament phosphorylation, proton mobility and magnetisation transfer in multiple sclerosis normal appearing white matter
    • Petzold A, Tozer DJ, Schmierer K. Axonal damage in the making: neurofilament phosphorylation, proton mobility and magnetisation transfer in multiple sclerosis normal appearing white matter. Exp Neurol. 2011 ; 232: 234-239
    • (2011) Exp Neurol , vol.232 , pp. 234-239
    • Petzold, A.1    Tozer, D.J.2    Schmierer, K.3
  • 33
    • 0025142225 scopus 로고
    • Perikaryal neurofilament phosphorylation in axotomized and 6-OH-dopamine-lesioned CNS neurons
    • Klosen P, Anderton BH, et al. Perikaryal neurofilament phosphorylation in axotomized and 6-OH-dopamine-lesioned CNS neurons. Brain Res. 1990 ; 526: 259-269
    • (1990) Brain Res , vol.526 , pp. 259-269
    • Klosen, P.1    Anderton, B.H.2
  • 34
    • 42049107093 scopus 로고    scopus 로고
    • Regulation of neurofilament dynamics by phosphorylation
    • Shea TB, Chan WK. Regulation of neurofilament dynamics by phosphorylation. Eur J Neurosci. 2008 ; 27: 1893-1901
    • (2008) Eur J Neurosci , vol.27 , pp. 1893-1901
    • Shea, T.B.1    Chan, W.K.2
  • 35
    • 70349232336 scopus 로고    scopus 로고
    • Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss
    • Sobottka B, Harrer MD, Ziegler U, et al. Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss. Am J Pathol. 2009 ; 175: 1160-1166
    • (2009) Am J Pathol , vol.175 , pp. 1160-1166
    • Sobottka, B.1    Harrer, M.D.2    Ziegler, U.3
  • 36
    • 84863458478 scopus 로고    scopus 로고
    • Axonopathy Is Associated with Complex Axonal Transport Defects in a Model of Multiple Sclerosis
    • Kreutzer M, Seehusen F, Kreutzer R, et al. Axonopathy Is Associated with Complex Axonal Transport Defects in a Model of Multiple Sclerosis. Brain Pathol. 2011 ;:
    • (2011) Brain Pathol
    • Kreutzer, M.1    Seehusen, F.2    Kreutzer, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.