-
1
-
-
34547616992
-
Phenotype of bone metastases of non-small cell lung cancer: epidermal growth factor receptor expression and K-RAS mutational status
-
Badalian G., et al. Phenotype of bone metastases of non-small cell lung cancer: epidermal growth factor receptor expression and K-RAS mutational status. Pathology Oncology Research 2007, 13:99-104.
-
(2007)
Pathology Oncology Research
, vol.13
, pp. 99-104
-
-
Badalian, G.1
-
2
-
-
0037037789
-
Chromosomal imbalances in human lung cancer
-
Balsara B.R., Testa J.R. Chromosomal imbalances in human lung cancer. Oncogene 2002, 21:6877-6883.
-
(2002)
Oncogene
, vol.21
, pp. 6877-6883
-
-
Balsara, B.R.1
Testa, J.R.2
-
3
-
-
78649760112
-
Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma
-
Bronte G., et al. Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma. Cancer Treatment Reviews 2010, 36(Suppl. 3):S21-S29.
-
(2010)
Cancer Treatment Reviews
, vol.36
, Issue.SUPPL. 3
-
-
Bronte, G.1
-
4
-
-
0025276890
-
Intratumoral heterogeneity of DNA content in lung cancer
-
Carey F.A., et al. Intratumoral heterogeneity of DNA content in lung cancer. Cancer 1990, 65:2266-2269.
-
(1990)
Cancer
, vol.65
, pp. 2266-2269
-
-
Carey, F.A.1
-
5
-
-
77952822151
-
KRAS mutation status in primary nonsmall cell lung cancer and matched metastases
-
Cortot A.B., et al. KRAS mutation status in primary nonsmall cell lung cancer and matched metastases. Cancer 2010, 116:2682-2687.
-
(2010)
Cancer
, vol.116
, pp. 2682-2687
-
-
Cortot, A.B.1
-
6
-
-
78651330430
-
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
-
Forbes S.A., et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Research 2011, 39:D945-D950.
-
(2011)
Nucleic Acids Research
, vol.39
-
-
Forbes, S.A.1
-
7
-
-
0034950354
-
Molecular genetic abnormalities in the pathogenesis of human lung cancer
-
Forgacs E., et al. Molecular genetic abnormalities in the pathogenesis of human lung cancer. Pathology Oncology Research 2001, 7:6-13.
-
(2001)
Pathology Oncology Research
, vol.7
, pp. 6-13
-
-
Forgacs, E.1
-
8
-
-
77349103908
-
KRAS mutation: comparison of testing methods and tissue sampling techniques in colon cancer
-
Franklin W.A., et al. KRAS mutation: comparison of testing methods and tissue sampling techniques in colon cancer. Journal of Molecular Diagnostics 2010, 12:43-50.
-
(2010)
Journal of Molecular Diagnostics
, vol.12
, pp. 43-50
-
-
Franklin, W.A.1
-
9
-
-
84863723714
-
A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens
-
Gonzalez de Castro D., et al. A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens. British Journal of Cancer 2012, 107:345-351.
-
(2012)
British Journal of Cancer
, vol.107
, pp. 345-351
-
-
Gonzalez de Castro, D.1
-
10
-
-
0032975370
-
Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small-cell lung cancer
-
Graziano S.L., et al. Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small-cell lung cancer. Journal of Clinical Oncology 1999, 17:668-675.
-
(1999)
Journal of Clinical Oncology
, vol.17
, pp. 668-675
-
-
Graziano, S.L.1
-
11
-
-
79960051265
-
Therapeutic strategies for targeting ras proteins
-
Gysin S., et al. Therapeutic strategies for targeting ras proteins. Genes & Cancer 2011, 2:359-372.
-
(2011)
Genes & Cancer
, vol.2
, pp. 359-372
-
-
Gysin, S.1
-
12
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
13
-
-
84859583692
-
KRAS and BRAF mutation analysis in routine molecular diagnostics: comparison of three testing methods on formalin-fixed, paraffin-embedded tumor-derived DNA
-
Heideman D.A., et al. KRAS and BRAF mutation analysis in routine molecular diagnostics: comparison of three testing methods on formalin-fixed, paraffin-embedded tumor-derived DNA. Journal of Molecular Diagnostics 2012, 14:247-255.
-
(2012)
Journal of Molecular Diagnostics
, vol.14
, pp. 247-255
-
-
Heideman, D.A.1
-
14
-
-
70349342712
-
EML4-ALK: honing in on a new target in non-small-cell lung cancer
-
Horn L., Pao W. EML4-ALK: honing in on a new target in non-small-cell lung cancer. Journal of Clinical Oncology 2009, 27:4232-4235.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. 4232-4235
-
-
Horn, L.1
Pao, W.2
-
15
-
-
0027407823
-
K-ras mutations in human adenocarcinoma of the lung: association with smoking and occupational exposure to asbestos
-
Husgafvel-Pursiainen K., et al. K-ras mutations in human adenocarcinoma of the lung: association with smoking and occupational exposure to asbestos. International Journal of Cancer 1993, 53:250-256.
-
(1993)
International Journal of Cancer
, vol.53
, pp. 250-256
-
-
Husgafvel-Pursiainen, K.1
-
17
-
-
51449101924
-
Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC
-
Kalikaki A., et al. Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC. British Journal of Cancer 2008, 99:923-929.
-
(2008)
British Journal of Cancer
, vol.99
, pp. 923-929
-
-
Kalikaki, A.1
-
18
-
-
9044221762
-
Detection of K-ras mutations in lung carcinomas: relationship to prognosis
-
Keohavong P., et al. Detection of K-ras mutations in lung carcinomas: relationship to prognosis. Clinical Cancer Research 1996, 2:411-418.
-
(1996)
Clinical Cancer Research
, vol.2
, pp. 411-418
-
-
Keohavong, P.1
-
19
-
-
33846641709
-
High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer
-
Krypuy M., et al. High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer. BMC Cancer 2006, 6:295.
-
(2006)
BMC Cancer
, vol.6
, pp. 295
-
-
Krypuy, M.1
-
20
-
-
79958266804
-
Roles of EGFR and KRAS mutations in the treatment of patients with non-small-cell lung cancer
-
Langer C.J. Roles of EGFR and KRAS mutations in the treatment of patients with non-small-cell lung cancer. P T 2011, 36:263-279.
-
(2011)
P T
, vol.36
, pp. 263-279
-
-
Langer, C.J.1
-
21
-
-
43249116705
-
Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing
-
Li J., et al. Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing. Nature Medicine 2008, 14:579-584.
-
(2008)
Nature Medicine
, vol.14
, pp. 579-584
-
-
Li, J.1
-
22
-
-
33646228635
-
KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
-
Lievre A., et al. KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Research 2006, 66:3992-3995.
-
(2006)
Cancer Research
, vol.66
, pp. 3992-3995
-
-
Lievre, A.1
-
23
-
-
40049100818
-
Prognostic and therapeutic implications of EGFR and KRAS mutations in resected lung adenocarcinoma
-
Marks J.L., et al. Prognostic and therapeutic implications of EGFR and KRAS mutations in resected lung adenocarcinoma. Journal of Thoracic Oncology 2008, 3:111-116.
-
(2008)
Journal of Thoracic Oncology
, vol.3
, pp. 111-116
-
-
Marks, J.L.1
-
24
-
-
84871920961
-
Consistent mutation status within histologically heterogeneous lung cancer lesions
-
Mattsson J.S., et al. Consistent mutation status within histologically heterogeneous lung cancer lesions. Histopathology 2012, 61:744-748.
-
(2012)
Histopathology
, vol.61
, pp. 744-748
-
-
Mattsson, J.S.1
-
25
-
-
44249086425
-
Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship
-
Molina J.R., et al. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clinic Proceedings 2008, 83:584-594.
-
(2008)
Mayo Clinic Proceedings
, vol.83
, pp. 584-594
-
-
Molina, J.R.1
-
26
-
-
0031938490
-
A prospective study of K-ras mutations in the plasma of pancreatic cancer patients
-
Mulcahy H.E., et al. A prospective study of K-ras mutations in the plasma of pancreatic cancer patients. Clinical Cancer Research 1998, 4:271-275.
-
(1998)
Clinical Cancer Research
, vol.4
, pp. 271-275
-
-
Mulcahy, H.E.1
-
27
-
-
79960894047
-
Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study
-
O'Byrne K.J., et al. Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study. The Lancet Oncology 2011, 12:795-805.
-
(2011)
The Lancet Oncology
, vol.12
, pp. 795-805
-
-
O'Byrne, K.J.1
-
28
-
-
0028219052
-
Detection of c-Ki-ras gene mutation in paraffin sections of adenocarcinoma and atypical bronchioloalveolar cell hyperplasia of human lung
-
Ohshima S., et al. Detection of c-Ki-ras gene mutation in paraffin sections of adenocarcinoma and atypical bronchioloalveolar cell hyperplasia of human lung. Virchows Archiv 1994, 424:129-134.
-
(1994)
Virchows Archiv
, vol.424
, pp. 129-134
-
-
Ohshima, S.1
-
30
-
-
78149249388
-
Personalized medicine in non-small-cell lung cancer: is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy?
-
Roberts P.J., et al. Personalized medicine in non-small-cell lung cancer: is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy?. Journal of Clinical Oncology 2010, 28:4769-4777.
-
(2010)
Journal of Clinical Oncology
, vol.28
, pp. 4769-4777
-
-
Roberts, P.J.1
-
31
-
-
0023271954
-
Mutational activation of the K-ras oncogene. A possible pathogenetic factor in adenocarcinoma of the lung
-
Rodenhuis S., et al. Mutational activation of the K-ras oncogene. A possible pathogenetic factor in adenocarcinoma of the lung. The New England Journal of Medicine 1987, 317:929-935.
-
(1987)
The New England Journal of Medicine
, vol.317
, pp. 929-935
-
-
Rodenhuis, S.1
-
32
-
-
0021362206
-
Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient
-
Santos E., et al. Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient. Science 1984, 223:661-664.
-
(1984)
Science
, vol.223
, pp. 661-664
-
-
Santos, E.1
-
33
-
-
0346958238
-
Tissue microarrays in drug discovery
-
Sauter G., et al. Tissue microarrays in drug discovery. Nature Reviews. Drug Discovery 2003, 2:962-972.
-
(2003)
Nature Reviews. Drug Discovery
, vol.2
, pp. 962-972
-
-
Sauter, G.1
-
34
-
-
68049088934
-
EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases
-
Schmid K., et al. EGFR/KRAS/BRAF mutations in primary lung adenocarcinomas and corresponding locoregional lymph node metastases. Clinical Cancer Research 2009, 15:4554-4560.
-
(2009)
Clinical Cancer Research
, vol.15
, pp. 4554-4560
-
-
Schmid, K.1
-
35
-
-
78651079558
-
A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer
-
Su Z., et al. A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer. Journal of Molecular Diagnostics 2011, 13:74-84.
-
(2011)
Journal of Molecular Diagnostics
, vol.13
, pp. 74-84
-
-
Su, Z.1
-
36
-
-
79952703873
-
Comparison of KRAS and EGFR gene status between primary non-small cell lung cancer and local lymph node metastases: implications for clinical practice
-
Sun L., et al. Comparison of KRAS and EGFR gene status between primary non-small cell lung cancer and local lymph node metastases: implications for clinical practice. Journal of Experimental & Clinical Cancer Research 2011, 30:30.
-
(2011)
Journal of Experimental & Clinical Cancer Research
, vol.30
, pp. 30
-
-
Sun, L.1
-
37
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E., et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. The New England Journal of Medicine 2009, 360:1408-1417.
-
(2009)
The New England Journal of Medicine
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
-
38
-
-
0027166695
-
K-ras oncogene activation in lung adenocarcinomas from former smokers. Evidence that K-ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung
-
Westra W.H., et al. K-ras oncogene activation in lung adenocarcinomas from former smokers. Evidence that K-ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung. Cancer 1993, 72:432-438.
-
(1993)
Cancer
, vol.72
, pp. 432-438
-
-
Westra, W.H.1
-
39
-
-
0029933372
-
K-ras oncogene activation in atypical alveolar hyperplasias of the human lung
-
Westra W.H., et al. K-ras oncogene activation in atypical alveolar hyperplasias of the human lung. Cancer Research 1996, 56:2224-2228.
-
(1996)
Cancer Research
, vol.56
, pp. 2224-2228
-
-
Westra, W.H.1
|