A continuous kilogram-scale process for the manufacture of o-difluorobenzene

Organic Process Research and Development

Volumn 16, Issue 10, 2012, Pages 1669-1672

  Yu, Zhiqun ^a   Lv, Yanwen ^a,b   Yu, Chuanming ^a  

^a ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^b QUZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMERICAN CHEMICAL SOCIETY; CONTINUOUS FLOW REACTORS; CONTINUOUS FLOWS; COSOLVENTS; DIAZOTIZATION; REACTION TEMPERATURE;

EID: 84870951127     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op300127x     Document Type: Article

References (22)

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21. SAFETY NOTE: Heating of diazonium salts in this way is potentially hazardous, depending on the stability of the diazonium salt and can result in corrosive and poisonous off-gases.
22. No obvious corrosion problems of the reacting tube have been found during our experiment, while the life of silicone tubing was only hundreds of hours.