Lactic acid bacteria: A promising alternative for recombinant protein production

Microbial Cell Factories

Volumn 11, Issue , 2012, Pages

  García Fruitós, Elena ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; NUCLEASE; RECOMBINANT PROTEIN;

BACILLUS SUBTILIS; BIOMEDICINE; EDITORIAL; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; LACTIC ACID BACTERIUM; LACTOCOCCUS LACTIS; NONHUMAN; PROTEIN EXPRESSION;

BACILLUS SUBTILIS; ESCHERICHIA COLI; LACTOCOCCUS LACTIS; RECOMBINANT PROTEINS;

EID: 84870939870     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-11-157     Document Type: Editorial

References (27)

1. Pontes DS, de Azevedo MS, Chatel JM, Langella P, Azevedo V, Miyoshi A. Lactococcus lactis as a live vector: heterologous protein production and DNA delivery systems. Protein Expr Purif 2011, 79:165-175. 10.1016/j.pep.2011.06.005, 21704169.
2. de Vos WM. Systems solutions by lactic acid bacteria: from paradigms to practice. Microb Cell Fact 2011, 10(Suppl 1):S2. 10.1186/1475-2859-10-S1-S2, 3231926, 21995776.
3. Teusink B, Bachmann H, Molenaar D. Systems biology of lactic acid bacteria: a critical review. Microb Cell Fact 2011, 10(Suppl 1):S11. 10.1186/1475-2859-10-S1-S11, 3231918, 21995498.
4. Konings WN, Kok J, Kuipers OP, Poolman B. Lactic acid bacteria: the bugs of the new millennium. Curr Opin Microbiol 2000, 3:276-282. 10.1016/S1369-5274(00)00089-8, 10851157.
5. Rhee SJ, Lee JE, Lee CH. Importance of lactic acid bacteria in Asian fermented foods. Microb Cell Fact 2011, 10(Suppl 1):S5. 10.1186/1475-2859-10-S1-S5, 3231931, 21995342.
6. Mills S, Stanton C, Fitzgerald GF, Ross RP. Enhancing the stress responses of probiotics for a lifestyle from gut to product and back again. Microb Cell Fact 2011, 10(Suppl 1):S19. 10.1186/1475-2859-10-S1-S19, 3231925, 21995734.
7. Forssten SD, Sindelar CW, Ouwehand AC. Probiotics from an industrial perspective. Anaerobe 2011, 17:410-413. 10.1016/j.anaerobe.2011.04.014, 21549209.
8. Kumari A, Catanzaro R, Marotta F. Clinical importance of lactic acid bacteria: a short review. Acta Biomed 2011, 82:177-180.
9. Wells JM. Immunomodulatory mechanisms of lactobacilli. Microb Cell Fact 2011, 10(Suppl 1):S17. 10.1186/1475-2859-10-S1-S17, 3231924, 21995674.
10. Gleinser M, Grimm V, Zhurina D, Yuan J, Riedel CU. Improved adhesive properties of recombinant bifidobacteria expressing the Bifidobacterium bifidum-specific lipoprotein BopA. Microb Cell Fact 2012, 11:80. 10.1186/1475-2859-11-80, 3408352, 22694891.
11. Douillard FP, O'Connell-Motherway M, Cambillau C, van Sinderen D. Expanding the molecular toolbox for Lactococcus lactis: construction of an inducible thioredoxin gene fusion expression system. Microb Cell Fact 2011, 10:66. 10.1186/1475-2859-10-66, 3162883, 21827702.
12. Zweers JC, Barak I, Becher D, Driessen AJ, Hecker M, Kontinen VP, et al. Towards the development of Bacillus subtilis as a cell factory for membrane proteins and protein complexes. Microb Cell Fact 2008, 7:10. 10.1186/1475-2859-7-10, 2323362, 18394159.
13. Westers L, Westers H, Quax WJ. Bacillus subtilis as cell factory for pharmaceutical proteins: a biotechnological approach to optimize the host organism. Biochim Biophys Acta 2004, 1694:299-310. 10.1016/j.bbamcr.2004.02.011, 15546673.
14. Petsch D, Anspach FB. Endotoxin removal from protein solutions. J Biotechnol 2000, 76:97-119. 10.1016/S0168-1656(99)00185-6, 10656326.
15. Ferrer-Miralles N, Domingo-Espin J, Corchero JL, Vazquez E, Villaverde A. Microbial factories for recombinant pharmaceuticals. Microb Cell Fact 2009, 8:17. 10.1186/1475-2859-8-17, 2669800, 19317892.
16. Schmidt FR. Recombinant expression systems in the pharmaceutical industry. Appl Microbiol Biotechnol 2004, 65:363-372. 10.1007/s00253-004-1656-9, 15480623.
17. Liu S, Tobias R, McClure S, Styba G, Shi Q, Jackowski G. Removal of endotoxin from recombinant protein preparations. Clin Biochem 1997, 30:455-463. 10.1016/S0009-9120(97)00049-0, 9316739.
18. Morello E, Bermudez-Humaran LG, Llull D, Sole V, Miraglio N, Langella P, et al. Lactococcus lactis, an efficient cell factory for recombinant protein production and secretion. J Mol Microbiol Biotechnol 2008, 14:48-58. 10.1159/000106082, 17957110.
19. Papagianni M. Recent advances in engineering the central carbon metabolism of industrially important bacteria. Microb Cell Fact 2012, 11:50. 10.1186/1475-2859-11-50, 3461431, 22545791.
20. Marciniak BC, Trip H, van-der Veek PJ, Kuipers OP. Comparative transcriptional analysis of bacillus subtilis cells overproducing either secreted proteins, lipoproteins or membrane proteins. Microb Cell Fact 2012, 11:66. 10.1186/1475-2859-11-66, 3514339, 22624725.
21. Nouaille S, Ribeiro LA, Miyoshi A, Pontes D, Le LY, Oliveira SC, et al. Heterologous protein production and delivery systems for Lactococcus lactis. Genet Mol Res 2003, 2:102-111.
22. Tremillon N, Issaly N, Mozo J, Duvignau T, Ginisty H, Devic E, et al. Production and purification of staphylococcal nuclease in Lactococcus lactis using a new expression-secretion system and a pH-regulated mini-reactor. Microb Cell Fact 2010, 9:37. 10.1186/1475-2859-9-37, 2887397, 20492646.
23. Glenting J, Poulsen LK, Kato K, Madsen SM, Frokiaer H, Wendt C, et al. Production of recombinant peanut allergen Ara h 2 using lactococcus lactis. Microb Cell Fact 2007, 6:28. 10.1186/1475-2859-6-28, 2000909, 17711578.
24. Bermudez-Humaran LG, Cortes-Perez NG, L'Haridon R, Langella P. Production of biological active murine IFN-gamma by recombinant Lactococcus lactis. FEMS Microbiol Lett 2008, 280:144-149. 10.1111/j.1574-6968.2007.01038.x, 18248432.
25. Bahey-El-Din M, Gahan CG. Lactococcus lactis-based vaccines: current status and future perspectives. Hum Vaccin 2011, 7:106-109. 10.4161/hv.7.1.13631, 21263226.
26. Bahey-El-Din M, Gahan CG, Griffin BT. Lactococcus lactis as a cell factory for delivery of therapeutic proteins. Curr Gene Ther 2010, 10:34-45. 10.2174/156652310790945557, 20156189.
27. Arendt EK, Moroni A, Zannini E. Medical nutrition therapy: use of sourdough lactic acid bacteria as a cell factory for delivering functional biomolecules and food ingredients in gluten free bread. Microb Cell Fact 2011, 10(Suppl 1):S15. 10.1186/1475-2859-10-S1-S15, 3231922, 21995616.